Mindfulness-Based Stress Reduction (MBSR) + Psilocybin-Assisted Psychotherapy (PAP) for Depression

Huntsman Mental Health Institute, Salt Lake City, UT
Depression+1 More ConditionsPsilocybin - Drug
Eligibility
18+
All Sexes

Study Summary

This trial will study the efficacy of MBSR + psilocybin psychotherapy for frontline healthcare workers battling depression & burnout from the pandemic.

Eligible Conditions
  • Depression
  • Burnout

Treatment Effectiveness

Phase-Based Effectiveness

1 of 3
Phase < 1

Study Objectives

1 Primary · 7 Secondary · Reporting Duration: Study enrollment to 2 weeks and 6 months post intervention

6 months
Mental Depression
Month 6
Storyline Health Integrative Assessment
Week 2
Phosphorus
Phosphorus
Month 6
Personality inventories
Week 2
Phosphorus
Phosphorus
Week 2
State and Trait Mindfulness

Trial Safety

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

2 Treatment Groups

Mindfulness-Based Stress Reduction (MBSR)
1 of 2
Mindfulness-Based Stress Reduction (MBSR) + Psilocybin-Assisted Psychotherapy (P...
1 of 2

Active Control

Experimental Treatment

24 Total Participants · 2 Treatment Groups

Primary Treatment: Mindfulness-Based Stress Reduction (MBSR) + Psilocybin-Assisted Psychotherapy (PAP) · No Placebo Group · Phase < 1

Mindfulness-Based Stress Reduction (MBSR) + Psilocybin-Assisted Psychotherapy (PAP)Experimental Group · 2 Interventions: Psilocybin, Mindfulness-Based Stress Reduction (MBSR) · Intervention Types: Drug, Behavioral
Mindfulness-Based Stress Reduction (MBSR)
Behavioral
ActiveComparator Group · 1 Intervention: Mindfulness-Based Stress Reduction (MBSR) · Intervention Types: Behavioral
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Psilocybin
2021
Completed Phase 2
~590
Mindfulness-Based Stress Reduction (MBSR)
2016
Completed Phase 2
~1260

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: study enrollment to 2 weeks and 6 months post intervention

Who is running the clinical trial?

Heffter Research InstituteOTHER
13 Previous Clinical Trials
486 Total Patients Enrolled
3 Trials studying Depression
104 Patients Enrolled for Depression
University of UtahLead Sponsor
1,022 Previous Clinical Trials
1,776,351 Total Patients Enrolled
19 Trials studying Depression
2,284 Patients Enrolled for Depression
Usona InstituteOTHER
11 Previous Clinical Trials
494 Total Patients Enrolled
6 Trials studying Depression
338 Patients Enrolled for Depression

Eligibility Criteria

Age 18+ · All Participants · 18 Total Inclusion Criteria

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Who else is applying?

What state do they live in?
Utah100.0%
What site did they apply to?
Huntsman Mental Health Institute100.0%
What portion of applicants met pre-screening criteria?
Did not meet criteria100.0%

Frequently Asked Questions

Can individuals currently apply to participate in this research?

"As per clinicaltrials.gov, this investigation is still enrolling patients and remains open to applications since its debut on February 1st 2023 and recent amendment on April 26th 2023." - Anonymous Online Contributor

Unverified Answer

How many individuals are currently involved in this research endeavor?

"Affirmative. Clinicaltrials.gov confirms that, since its inception on 2nd January 2023 and most recent update on 26th April 2023, this medical trial is actively seeking 24 volunteers from a single site." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.