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Behavioural Intervention

24h-Ambulatory Blood Pressure for High Blood Pressure (DIISCCO Trial)

N/A
Waitlist Available
Led By Anil Nigam, MD
Research Sponsored by Anil Nigam
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at baseline and after twelve weeks of intervention
Awards & highlights

DIISCCO Trial Summary

This trial will compare the effects of HIIT vs. hydrochlorothiazide in prehypertensive older adults to see if HIIT can be as effective as medication in lowering blood pressure.

Eligible Conditions
  • High Blood Pressure
  • Exercise

DIISCCO Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~before and after twelve weeks of intervention
This trial's timeline: 3 weeks for screening, Varies for treatment, and before and after twelve weeks of intervention for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
24h-Ambulatory Blood Pressure
Secondary outcome measures
Cardiovascular evaluation
Cognitive functions
Flow Mediated Dilatation (FMD)

DIISCCO Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: High Intensity Interval Training (HIIT)Experimental Treatment1 Intervention
For the twelve weeks of intervention, participants will have three training sessions per week. Each session will be done on a cycle ergometer and will last approximately 40 minutes. Participants will be supervised by certified kinesiologists and their training programs will be revised every four weeks.
Group II: HydroChloroThiazideActive Control1 Intervention
For this group, participants have to take a diuretic (12,5 mg of Hydrochlorothiazide) daily prescribed by the doctor of this study, for twelve weeks. Participants should also maintain the same lifestyle habits that they had before the study.

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Who is running the clinical trial?

Anil NigamLead Sponsor
Anil Nigam, MDPrincipal InvestigatorMontreal Heart Institute
2 Previous Clinical Trials
50 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Effect of High-Intensity Interval Training Compared to Hydrochlorothiazide on Ambulatory Blood Pressure
Anil Nigam 2018. "Effect of High-Intensity Interval Training Compared to Hydrochlorothiazide on Ambulatory Blood Pressure". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04103411.
All > Blood Pressure
~9 spots leftby May 2025
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