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Calcium chloride for Postpartum Hemorrhage (CALBLOC Trial)
CALBLOC Trial Summary
This trial will establish the effect of 1 gram of intravenous calcium chloride upon quantitative blood loss and uterine tone during cesarean delivery in parturients with high risk of uterine atony.
- Postpartum Hemorrhage
- Uterine Atony
- Uterine Atony With Hemorrhage
- Cesarean Section Complications
CALBLOC Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.CALBLOC Trial Design
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Who is running the clinical trial?
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- You have taken medication for high blood pressure called calcium channel blocker within the last 24 hours.You have a pre-existing heart condition.
- Group 1: Saline placebo
- Group 2: Calcium chloride
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Could you please share how many people are involved in this research project?
"As of right now, this clinical trial is not looking for any more patients. This information was taken from the date that the trial was first posted (1/1/2023) and when it was last edited (2/4/2022). However, there are currently 416 trials actively recruiting patients with postpartum hemorrhage and 13 studies seeking participants for Calcium chloride research."
How can I become a part of this experiment?
"Women who have recently given birth and are between 18-55 years old may be accepted into this study on postpartum hemorrhage. A total of 120 patients will be enrolled."
For what sorts of medical conditions is calcium chloride regularly employed?
"More often than not, calcium chloride is used to treat kidney failure that has come on suddenly. That being said, it can also be an effective way to manage other conditions like calcium channel blockers, diarrhea, and beta blocker overdoses."
What other research studies have used Calcium chloride as a treatment?
"There are currently 13 active clinical trials investigating the use of calcium chloride, with 3 of those trials in Phase 3. Most of the studies for calcium chloride are being conducted out of Pittsburgh, Pennsylvania, but there are 17 total locations where studies are taking place."
Are the subjects of this research project restricted to a certain age group?
"Individuals who are between 18-55 years old may participate in this clinical trial."
Are participants being enrolled in this experiment right now?
"This study is no longer looking for participants. Trial information indicates that the first posting was on 1/1/2023 and the last update occurred on 2/4/2022. There are other options available, including 416 clinical trials searching for patients with postpartum hemorrhage and 13 studies involving calcium chloride currently enrolling new participants."
Has the FDA cleared calcium chloride for use?
"There is some clinical data that supports the efficacy of calcium chloride, and it has received multiple rounds of support for safety, so we have given it a score of 3."
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