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Children's Hospital of Eastern Ontario

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OTTAWA, Ontario K1H 8L1
Global Leader in Leukemia
Global Leader in Lymphoblastic Leukemia-Lymphoma
Conducts research for Tumors
Conducts research for Lymphoid Leukemia
Conducts research for Acute Lymphoblastic Leukemia
326 reported clinical trials
20 medical researchers
Photo of Children's Hospital of Eastern Ontario in OTTAWAPhoto of Children's Hospital of Eastern Ontario in OTTAWAPhoto of Children's Hospital of Eastern Ontario in OTTAWA

Summary

Children's Hospital of Eastern Ontario is a medical facility located in OTTAWA, Ontario. This center is recognized for care of Leukemia, Lymphoblastic Leukemia-Lymphoma, Tumors, Lymphoid Leukemia, Acute Lymphoblastic Leukemia and other specialties. Children's Hospital of Eastern Ontario is involved with conducting 326 clinical trials across 508 conditions. There are 20 research doctors associated with this hospital, such as Donna Johnston, MD, Hanns Lochmuller, MD, Sasha Carsen, MD, and Margaret Lawson, MD.

Area of expertise

1Leukemia
Global Leader
Children's Hospital of Eastern Ontario has run 53 trials for Leukemia. Some of their research focus areas include:
Stage II
BCR-ABL1 fusion positive
ABL-class fusion positive
2Lymphoblastic Leukemia-Lymphoma
Global Leader
Children's Hospital of Eastern Ontario has run 33 trials for Lymphoblastic Leukemia-Lymphoma. Some of their research focus areas include:
Stage II
BCR-ABL1 fusion positive
ABL-class fusion positive

Top PIs

Clinical Trials running at Children's Hospital of Eastern Ontario

Migraine
Leukemia
Acute Lymphoblastic Leukemia
Type 1 Diabetes
Ovarian Tumors
Rhabdomyosarcoma
Acute Myeloid Leukemia
Lymphoblastic Leukemia-Lymphoma
Ovarian Choriocarcinoma
Testicular Carcinoma
Image of trial facility.

Oral Atogepant Tablets

for Migraine

A migraine is a moderate to severe headache on one side of the head. A migraine attack is a headache that may be accompanied by throbbing, nausea, vomiting, sensitivity to light and sound, or other symptoms. A number of treatments are available for adults with migraine but there are limited approved treatments available for pediatric participants. The main goal of the study is to evaluate the safety and efficacy (how well treatment works) of a low-dose and high-dose of atogepant in pediatric participants between the ages of 6 and 17. Atogepant is a medicine currently approved to treat adults with episodic migraine (0 to 14 migraine days per month) and is being studied in pediatric participants between the ages of 6 and 17 with a history of episodic migraine. This is a Phase 3, randomized, double-blind study of atogepant in participants with a history of episodic migraine with an open-label pharmacokinetic substudy. Eligible participants will be randomized into 6 different groups. Participants between the ages of 12 and 17 will be randomized to receive placebo, low-dose atogepant, or high-dose atogepant for 12 weeks. Participants between the ages of 6 and 11 will also be randomized to receive placebo, low-dose atogepant, or high-dose atogepant for 12 weeks. The specific atogepant doses to be used in participants between the ages of 6 and 11 will be determined after the PK substudy is complete. Around 450 participants will be enrolled in approximately 100 sites. Placebo, low-dose atogepant, and high-dose atogepant are given as a tablet to take by mouth once a day. At the end of Week 12, participants will either undergo a follow-up visit 4 weeks after last study treatment or join an extension study where they can continue to receive atogepant for another 52 weeks. There may be a bigger responsibility for participants in this study. Participants will attend regular visits during the study at a hospital or clinic. The effects of treatment will be checked by medical assessments, blood tests, checking for side effects, and completing questionnaires.
Recruiting1 award Phase 34 criteria
Image of trial facility.

Erenumab

for Pediatric Migraine

This study is evaluating whether a drug may help reduce the number of migraine headaches in children and adolescents.
Recruiting1 award Phase 36 criteria
Image of trial facility.

Erenumab

for Migraine

This study is evaluating whether a drug may help reduce the number of migraine headaches in children and adolescents.
Recruiting1 award Phase 33 criteria

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Frequently asked questions

What kind of research happens at Children's Hospital of Eastern Ontario?
Children's Hospital of Eastern Ontario is a medical facility located in OTTAWA, Ontario. This center is recognized for care of Leukemia, Lymphoblastic Leukemia-Lymphoma, Tumors, Lymphoid Leukemia, Acute Lymphoblastic Leukemia and other specialties. Children's Hospital of Eastern Ontario is involved with conducting 326 clinical trials across 508 conditions. There are 20 research doctors associated with this hospital, such as Donna Johnston, MD, Hanns Lochmuller, MD, Sasha Carsen, MD, and Margaret Lawson, MD.
Where is Children's Hospital of Eastern Ontario located?
**The Children's Hospital of Eastern Ontario** - **Address:** 401 Smyth Road, Ottawa, ON K1H 8L1 - **Accessibility:** Easily accessible by public transit with OC Transpo buses stopping directly in front of the main campus. By car, it's approximately 10 minutes from downtown Ottawa and 20 minutes from the airport.
Who should I call to ask about financial aid or insurance network?
**Financial Assistance and Insurance Inquiries at Children's Hospital of Eastern Ontario (CHEO):** 1. **Assistance for Children with Severe Disabilities (ACSD):** This program aids parents with the extra costs of caring for a child with a disability. For application details, visit [ACSD Information](http://www.children.gov.on.ca/htdocs/English/topics/specialneeds/disabilities/index.aspx) or call (613) 787-4064. 2. **Special Services at Home (SSAH):** Designed for families caring for a child with a developmental or physical disability, or an adult with a developmental disability. Apply at [SSAH Program](http://www.children.gov.on.ca/htdocs/English/topics/specialneeds/specialservices/index.aspx) or call 1-800-267-5111 (ext. 2399 or 4064). 3. **Provincial Assistive Devices Program (ADP):** Offers financial assistance for equipment and supplies for those with physical disabilities. Contact the Ontario Ministry of Health and Long-Term Care's Assistive Devices Program for more information. For general inquiries, contact CHEO at (613) 737-7600 ext. 2158.
What insurance does Children's Hospital of Eastern Ontario accept?
The Children's Hospital of Eastern Ontario (CHEO) accepts various insurance plans, including OHIP for Ontario residents and RAMQ for Quebec residents. For a comprehensive list of accepted insurance plans, please contact the hospital directly or visit their official website.
What awards or recognition has Children's Hospital of Eastern Ontario received?
The Children's Hospital of Eastern Ontario (CHEO) in Ottawa is renowned for its excellence in research areas such as genetics, rare diseases, and cancer, among others. With over 500 discoveries each year, the CHEO Research Institute plays a crucial role in these achievements. Forbes has recognized CHEO as one of the top Canadian hospitals in 2021 and 2023, and it was also ranked among the top pediatric hospitals in Canada for patient experience in 2024.