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What is Ilevro
NepafenacThe Generic name of this drug
Treatment SummaryNepafenac is a medication used to treat pain and inflammation after cataract surgery. It is an NSAID (non-steroidal anti-inflammatory drug) that comes in the form of a prescription eye drop.
Nevanacis the brand name
Ilevro Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Nevanac
Nepafenac
2005
5
Approved as Treatment by the FDA
Nepafenac, also known as Nevanac, is approved by the FDA for 3 uses like Chronic Pain and Inflammation .Chronic Pain
Helps manage Pain
Inflammation
Helps manage Inflammation
Cataract Surgery
Helps manage Cataract Surgery
Effectiveness
How Ilevro Affects PatientsWhen Nepafenac ophthalmic suspension is taken three times a day, measurable amounts of Nepafenac and Amfenac are present in the blood after two and three hours respectively. On average, the maximum amount of Nepafenac and Amfenac in the blood was 0.310 and 0.422 nanograms per milliliter, respectively.
How Ilevro works in the bodyNepafenac is a drug that is changed in the body to amfenac, a type of pain reliever. Amfenac works by blocking the activity of two enzymes, COX1 and COX2. This helps reduce inflammation and pain.
When to interrupt dosage
The recommended measure of Ilevro is contingent upon the diagnosed condition, for example Inflammation, Cataract Surgery and Chronic Pain. The quantity of dosage fluctuates, according to the administration mode (e.g. Suspension / drops or Ophthalmic) featured in the table beneath.Condition
Dosage
Administration
Chronic Pain
, 1.0 mg/mL, 3.0 mg/mL, 0.3 %, 0.1 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic
Inflammation
, 1.0 mg/mL, 3.0 mg/mL, 0.3 %, 0.1 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic
Cataract Surgery
, 1.0 mg/mL, 3.0 mg/mL, 0.3 %, 0.1 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic
Warnings
Ilevro ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Common Ilevro Drug Interactions
Drug Name
Risk Level
Description
Valproic acid
Minor
The protein binding of Valproic acid can be decreased when combined with Nepafenac.
Acemetacin
Moderate
The risk or severity of adverse effects can be increased when Nepafenac is combined with Acemetacin.
Acetylsalicylic acid
Moderate
The therapeutic efficacy of Acetylsalicylic acid can be decreased when used in combination with Nepafenac.
Alclofenac
Moderate
The risk or severity of adverse effects can be increased when Nepafenac is combined with Alclofenac.
Alminoprofen
Moderate
The risk or severity of adverse effects can be increased when Nepafenac is combined with Alminoprofen.
Ilevro Toxicity & Overdose RiskApplying non-steroidal anti-inflammatory drugs to the eyes can lead to increased bleeding in the eye area during eye surgery.
Ilevro Novel Uses: Which Conditions Have a Clinical Trial Featuring Ilevro?
357 active studies are currently being undertaken to assess the potential of Ilevro in alleviating Inflammation, Chronic Pain and assisting with Cataract Surgery.Condition
Clinical Trials
Trial Phases
Inflammation
171 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 3, Phase 4
Chronic Pain
175 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Phase 4, Early Phase 1
Cataract Surgery
1 Actively Recruiting
Phase 4
Ilevro Reviews: What are patients saying about Ilevro?
5Patient Review
8/28/2016 I took this treatment once a day for 7 days, and then due to irritation from the antibiotic, I dropped down to 2 drops a day for 7 days. I had a sample bottle which only lasted me until day 11. From my experience, I think that one bottle would last if you're only taking 1 drop a day for two weeks. However, since I ran out before finishing the full 14 days, I had to get a prescription for the other eye. This medication is pricey, but my insurance did give me a special authorization and covered it.
5Patient Review
6/17/2017 Helped to relieve pain after a failed glaucoma surgery. Not as easy to apply as OTC eyedrops, but this was much more effective and long-lasting.
4Patient Review
10/29/20133.3Patient Review
1/1/2014 The bottle was very small and expensive. The design of the bottle tip was such that the medication would drip down the side of the bottle after application, wasting a small amount each time. Other eye drops I used had better tip design.
3Patient Review
3/22/2019 I used this once in the morning and evening for cataracts/LASIK and it did the job well. The only side effect was temporary blurring, but that was manageable. The bottle is really difficult to use though.
2Patient Review
3/26/2016 The bottle is rigid, and the fluid inside is very viscous. It barely lasted me three weeks. Since it's not a covered medication, unless you're careful with your usage, you'll end up having to pay for another bottle before you're supposed to.
1.7Patient Review
8/8/2014 The design of this dropper is very poor. There is only enough medicine for 25 days, so you have to be careful when using it.
Patient Q&A Section about ilevro
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What are the side effects of Ilevro eye drops?
"The sensation of a foreign body in the eye, increased intraocular pressure, a sticky sensation in the eye, eye or eyelid swelling, dry eye, crusting of the eyelids, eye discomfort or pain, and itchy eyes are all symptoms of conjunctivitis."
Answered by AI
What kind of drug is Ilevro?
"Ilevro is a non-steroidal anti-inflammatory drug (NSAID) that lessens pain and swelling in the eye due to surgery by stopping your body from making chemicals that cause inflammation."
Answered by AI
Is Ilevro a generic drug?
"At the moment, there is no cheaper alternative to Ilevro that has the same therapeutic effect in the United States. Be aware that there are many illegal online pharmacies that might try to sell you a generic version of Ilevro. These medicines could be fake and potentially dangerous."
Answered by AI