Ilevro

Chronic Pain, Inflammation, Cataract Surgery
Treatment
5 FDA approvals
20 Active Studies for Ilevro

What is Ilevro

NepafenacThe Generic name of this drug
Treatment SummaryNepafenac is a medication used to treat pain and inflammation after cataract surgery. It is an NSAID (non-steroidal anti-inflammatory drug) that comes in the form of a prescription eye drop.
Nevanacis the brand name
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Ilevro Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Nevanac
Nepafenac
2005
5

Approved as Treatment by the FDA

Nepafenac, also known as Nevanac, is approved by the FDA for 5 uses like Inflammation and Pain .
Inflammation
Helps manage Inflammation
Pain
Helps manage Pain
Chronic Pain
Helps manage Pain
Cataract Surgery
Helps manage Cataract Surgery
Inflammation
Helps manage Inflammation

Effectiveness

How Ilevro Affects PatientsWhen Nepafenac ophthalmic suspension is taken three times a day, measurable amounts of Nepafenac and Amfenac are present in the blood after two and three hours respectively. On average, the maximum amount of Nepafenac and Amfenac in the blood was 0.310 and 0.422 nanograms per milliliter, respectively.
How Ilevro works in the bodyNepafenac is a drug that is changed in the body to amfenac, a type of pain reliever. Amfenac works by blocking the activity of two enzymes, COX1 and COX2. This helps reduce inflammation and pain.

When to interrupt dosage

The recommended measure of Ilevro is contingent upon the diagnosed condition, for example Inflammation, Cataract Surgery and Chronic Pain. The quantity of dosage fluctuates, according to the administration mode (e.g. Suspension / drops or Ophthalmic) featured in the table beneath.
Condition
Dosage
Administration
Chronic Pain
, 1.0 mg/mL, 3.0 mg/mL, 0.3 %, 0.1 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic
Cataract Surgery
, 1.0 mg/mL, 3.0 mg/mL, 0.3 %, 0.1 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic
Inflammation
, 1.0 mg/mL, 3.0 mg/mL, 0.3 %, 0.1 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic

Warnings

Ilevro Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Ilevro.
Common Ilevro Drug Interactions
Drug Name
Risk Level
Description
Valproic acid
Minor
The protein binding of Valproic acid can be decreased when combined with Nepafenac.
Acemetacin
Moderate
The risk or severity of adverse effects can be increased when Nepafenac is combined with Acemetacin.
Acetylsalicylic acid
Moderate
The therapeutic efficacy of Acetylsalicylic acid can be decreased when used in combination with Nepafenac.
Alclofenac
Moderate
The risk or severity of adverse effects can be increased when Nepafenac is combined with Alclofenac.
Alminoprofen
Moderate
The risk or severity of adverse effects can be increased when Nepafenac is combined with Alminoprofen.
Ilevro Toxicity & Overdose RiskApplying non-steroidal anti-inflammatory drugs to the eyes can lead to increased bleeding in the eye area during eye surgery.
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Ilevro Novel Uses: Which Conditions Have a Clinical Trial Featuring Ilevro?

357 active studies are currently being undertaken to assess the potential of Ilevro in alleviating Inflammation, Chronic Pain and assisting with Cataract Surgery.
Condition
Clinical Trials
Trial Phases
Chronic Pain
141 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 4, Phase 3, Early Phase 1
Inflammation
64 Actively Recruiting
Not Applicable, Early Phase 1, Phase 1, Phase 2, Phase 3, Phase 4
Cataract Surgery
2 Actively Recruiting
Not Applicable, Phase 4

Ilevro Reviews: What are patients saying about Ilevro?

5Patient Review
8/28/2016
Ilevro for Inflammation of the Eye Following Surgery
I took this treatment once a day for 7 days, and then due to irritation from the antibiotic, I dropped down to 2 drops a day for 7 days. I had a sample bottle which only lasted me until day 11. From my experience, I think that one bottle would last if you're only taking 1 drop a day for two weeks. However, since I ran out before finishing the full 14 days, I had to get a prescription for the other eye. This medication is pricey, but my insurance did give me a special authorization and covered it.
5Patient Review
6/17/2017
Ilevro for Inflammation of the Eye Following Surgery
Helped to relieve pain after a failed glaucoma surgery. Not as easy to apply as OTC eyedrops, but this was much more effective and long-lasting.
4Patient Review
10/29/2013
Ilevro for Inflammation of the Eye Following Surgery
3.3Patient Review
1/1/2014
Ilevro for Inflammation of the Eye Following Surgery
The bottle was very small and expensive. The design of the bottle tip was such that the medication would drip down the side of the bottle after application, wasting a small amount each time. Other eye drops I used had better tip design.
3Patient Review
3/22/2019
Ilevro for Inflammation of the Eye Following Surgery
I used this once in the morning and evening for cataracts/LASIK and it did the job well. The only side effect was temporary blurring, but that was manageable. The bottle is really difficult to use though.
View All Reviews
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Patient Q&A Section about ilevro

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the drug Ilevro used for?

"This medication is used to relieve eye pain, irritation, and redness following cataract eye surgery. Nepafenac belongs to a class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs work by reducing swelling and inflammation."

Answered by AI

What are the side effects of Ilevro eye drops?

"The sensation of a foreign body in the eye, increased intraocular pressure, a sticky sensation in the eye, eye or eyelid swelling, dry eye, crusting of the eyelids, eye discomfort or pain, and itchy eyes are all symptoms of conjunctivitis."

Answered by AI

What kind of drug is Ilevro?

"Ilevro is a non-steroidal anti-inflammatory drug (NSAID) that lessens pain and swelling in the eye due to surgery by stopping your body from making chemicals that cause inflammation."

Answered by AI

Is Ilevro a generic drug?

"At the moment, there is no cheaper alternative to Ilevro that has the same therapeutic effect in the United States. Be aware that there are many illegal online pharmacies that might try to sell you a generic version of Ilevro. These medicines could be fake and potentially dangerous."

Answered by AI

Clinical Trials for Ilevro

Have you considered Ilevro clinical trials? We made a collection of clinical trials featuring Ilevro, we think they might fit your search criteria.
Have you considered Ilevro clinical trials? We made a collection of clinical trials featuring Ilevro, we think they might fit your search criteria.
Have you considered Ilevro clinical trials? We made a collection of clinical trials featuring Ilevro, we think they might fit your search criteria.
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