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What is Atelvia
Risedronic acidThe Generic name of this drug
Treatment SummaryRisedronic acid is a medication used to prevent bone loss and the weakening of bones caused by conditions such as osteoporosis and Paget’s disease. It is a type of bisphosphonate, a form of drug that works by blocking the removal of bone cells.
Actonelis the brand name
Atelvia Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Actonel
Risedronic acid
1998
61
Approved as Treatment by the FDA
Risedronic acid, also called Actonel, is approved by the FDA for 5 uses including Bone and Bones and Paget’s Disease .Bone and Bones
Used to treat increased bone mass in combination with Calcium
Paget’s Disease
Therapeutic procedure
Osteoporosis
Used to treat Osteoporosis in combination with Calcium
Postmenopause
Effectiveness
How Atelvia Affects PatientsRisedronate is a medicine that helps prevent bones from being broken down by blocking the activity of cells called osteoclasts.
How Atelvia works in the bodyRisedronatic acid binds to the bones and stops cells that break down bones, called osteoclasts, from doing their job. It does this by entering the cells, becoming acidic, and then inhibiting an enzyme called farnesyl pyrophosphate synthase. This stops the osteoclast from breaking down the bones, which decreases bone resorption.
When to interrupt dosage
The proposed dose of Atelvia is contingent upon the recognized condition, including Therapeutic procedure, Malignant Neoplasms and Postmenopause. The measure fluctuates as per the technique of delivery, as detailed in the table beneath.Condition
Dosage
Administration
Osteoporosis
30.0 mg, , 5.0 mg, 35.0 mg, 150.0 mg, 75.0 mg, 129.0 mg, 4.9 mg, 30.1 mg, 64.5 mg, 4.3 mg, 25.8 mg
Oral, , Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Granule, effervescent; Kit; Tablet, Granule, effervescent; Kit; Tablet - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Kit; Tablet, Kit; Tablet - Oral, Kit
Malignant Neoplasms
30.0 mg, , 5.0 mg, 35.0 mg, 150.0 mg, 75.0 mg, 129.0 mg, 4.9 mg, 30.1 mg, 64.5 mg, 4.3 mg, 25.8 mg
Oral, , Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Granule, effervescent; Kit; Tablet, Granule, effervescent; Kit; Tablet - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Kit; Tablet, Kit; Tablet - Oral, Kit
Postmenopause
30.0 mg, , 5.0 mg, 35.0 mg, 150.0 mg, 75.0 mg, 129.0 mg, 4.9 mg, 30.1 mg, 64.5 mg, 4.3 mg, 25.8 mg
Oral, , Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Granule, effervescent; Kit; Tablet, Granule, effervescent; Kit; Tablet - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Kit; Tablet, Kit; Tablet - Oral, Kit
Therapeutic procedure
30.0 mg, , 5.0 mg, 35.0 mg, 150.0 mg, 75.0 mg, 129.0 mg, 4.9 mg, 30.1 mg, 64.5 mg, 4.3 mg, 25.8 mg
Oral, , Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Granule, effervescent; Kit; Tablet, Granule, effervescent; Kit; Tablet - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Kit; Tablet, Kit; Tablet - Oral, Kit
Paget’s Disease
30.0 mg, , 5.0 mg, 35.0 mg, 150.0 mg, 75.0 mg, 129.0 mg, 4.9 mg, 30.1 mg, 64.5 mg, 4.3 mg, 25.8 mg
Oral, , Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Granule, effervescent; Kit; Tablet, Granule, effervescent; Kit; Tablet - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Kit; Tablet, Kit; Tablet - Oral, Kit
Bone and Bones
30.0 mg, , 5.0 mg, 35.0 mg, 150.0 mg, 75.0 mg, 129.0 mg, 4.9 mg, 30.1 mg, 64.5 mg, 4.3 mg, 25.8 mg
Oral, , Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Granule, effervescent; Kit; Tablet, Granule, effervescent; Kit; Tablet - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Kit; Tablet, Kit; Tablet - Oral, Kit
Warnings
Atelvia has three contraindications, so it ought not be administered when encountering any of the circumstances outlined in the following table.Atelvia ContraindicationsCondition
Risk Level
Notes
Hypocalcemia
Do Not Combine
Inability to stand or sit upright for at least 30 minutes
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Risedronic Acid may interact with Pulse Frequency
Common Atelvia Drug Interactions
Drug Name
Risk Level
Description
Etidronic acid
Minor
The risk or severity of adverse effects can be increased when Risedronic acid is combined with Etidronic acid.
Incadronic acid
Minor
The risk or severity of adverse effects can be increased when Risedronic acid is combined with Incadronic acid.
Tiludronic acid
Minor
The risk or severity of adverse effects can be increased when Risedronic acid is combined with Tiludronic acid.
Acipimox
Moderate
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Risedronic acid is combined with Acipimox.
Aluminium clofibrate
Moderate
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Risedronic acid is combined with Aluminium clofibrate.
Atelvia Toxicity & Overdose RiskTen percent of people taking this drug have reported experiencing back pain, joint pain, stomach pain, and indigestion. Other rare side effects include swelling of the face, skin rashes, eye irritation, and inflammation of the uvea. If someone takes too much of this drug, they may have reduced levels of calcium and phosphorus in their blood. Treatment options include drinking milk or taking antacids to bind the drug and reduce absorption. In more serious cases, a doctor may need to give the patient their stomach contents or intravenous calcium. A single overdose of this drug in rats was found to be 320 to 620 times the
Atelvia Novel Uses: Which Conditions Have a Clinical Trial Featuring Atelvia?
Fifty active trials are being conducted to assess the potential of Atelvia to treat Paget's Disease, Postmenopause and Malignant Neoplasms.Condition
Clinical Trials
Trial Phases
Postmenopause
5 Actively Recruiting
Phase 2, Not Applicable
Malignant Neoplasms
0 Actively Recruiting
Osteoporosis
40 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 4, Phase 3
Paget’s Disease
0 Actively Recruiting
Therapeutic procedure
0 Actively Recruiting
Bone and Bones
0 Actively Recruiting
Atelvia Reviews: What are patients saying about Atelvia?
5Patient Review
11/10/2014 I've been taking Atelvia for over a year and it's shown significant improvements in my condition with no negative side effects that I've experienced. My doctor is happy to keep me on the medication as long as they deem it safe, and I'm very content with the results.
5Patient Review
3/27/2015 This medication has been incredibly effective for me. I used to have to give myself a shot every day for two years with no improvement, but this drug has really helped.
4.7Patient Review
10/8/2014 I found this much easier to take than Actonel, and I've been taking it for years without any side effects. In most areas, it seems to have kept osteopenia at bay; however, in some areas it has progressed to osteoporosis. Overall, though, it did not improve my condition but prevented it from getting worse in most places.
4Patient Review
9/22/2014 I took Forteo to build up my bones and Atelvia to secure the gain (15%). It has been very effective over 3 years. I am 84 years old.
3Patient Review
12/6/2013 I was experiencing pain in my joints.
2.3Patient Review
11/18/2014 The stomach cramps, diarrhea and joint pain were really unpleasant. I gave it three doses before giving up.
2Patient Review
10/3/2015 I took Atelvia for 5 weeks and felt awful for the first three. I developed jaw pain in weeks four and five and had to get x-rays done by a dentist. They told me this medication was bad news and advised me to stop taking it immediately. I'm now on the hunt for more natural methods that don't come with such intense side effects.
2Patient Review
5/15/2015 This treatment unfortunately made my stomach upset and gave me indigestion, on top of making me feel generally ill like I had the flu.
1.7Patient Review
10/25/2013 I took a sample of this pill less than 24 hours ago and I already feel awful. I've got severe aches and pains, a nasty headache, and nausea. If you're considering this medication, I would not recommend it.
1.7Patient Review
7/8/2014 I unfortunately had to stop taking this medication after four weeks due to the severe stomach pain I was experiencing. It's been a real bummer because it seemed to be working well otherwise. If anyone knows of any other treatments for osteoporosis, please let me know.
1.7Patient Review
7/14/2014 This medication made me sick in so many ways. Constant diarrhea, headaches, flu symptoms, inflammation, etc. In my opinion, this drug should be taken off the market.
1.7Patient Review
2/22/2014 I've only taken one dose of this. It has been 4 days... had a headache the first day . Started getting Very noticeable pain in my femur bone, yesterday and today my ribs are aching. I've been using icepacks on both. I'm afraid to continue this medication... going to call the Dr. on Monday to consult with him.
1.7Patient Review
4/14/2014 I had awful intestinal cramps that lasted for weeks, and the diarrhea was incredibly unpleasant. I needed a medication to stop the muscle spasms. Thankfully, I will never have to take this again.
1.3Patient Review
2/25/2014 I really dislike the side effects of this drug. They include muscle tightness, leg and arm pain, common cold problems, esophagus problems, jaw bone and thigh bone fractures, among others.
1.3Patient Review
5/6/2014 This medicine made me very ill each time I took it. The first day would be fine, but by the second day I would become severely ill with abdominal pain, aches all over my body, diarrhea, low grade fever, and an extreme headache. These symptoms would persist for two to three days before gradually improving; however, even after taking the medication I would still experience abdominal pain whenever I ate anything.
1Patient Review
1/30/2014 I was really sick after taking this pill, and it's been a few days and I'm still not feeling great. I would never recommend this medication to anyone.
1Patient Review
5/31/2017 The first dose of this medication resulted in weeks of abdominal pain and diarrhea. I was unable to take the second dose as prescribed. This is not an effective treatment for me
1Patient Review
5/6/2014 For the last three days, I've been dealing with debilitating muscle pain.
Patient Q&A Section about atelvia
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How often do you take Atelvia?
"Atelvia may be used to treat osteoporosis in postmenopausal women. It is a delayed-release tablet that is taken once a week."
Answered by AI
What is Atelvia used for?
"Atelvia is a prescription medication used to treat osteoporosis in postmenopausal women. The longevity of Atelvia's efficacy is unknown. You should consult your physician periodically to see if Atelvia is still an appropriate medication for you."
Answered by AI
How long can you take Atelvia?
"Do as your doctor says when taking Atelvia. This includes following directions on the prescription label and reading all medication guides or instruction sheets. Your doctor may sometimes change your dose of the medication. Risedronate is commonly only taken for 3 to 5 years."
Answered by AI