1553 Participants Needed

OPTIONS Program for Osteoporosis

(OPTIONS Trial)

Recruiting at 1 trial location
KS
PD
Overseen ByPatricia Dykes, RN, PhD
Age: 65+
Sex: Any
Trial Phase: Academic
Sponsor: Brigham and Women's Hospital
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

What is the purpose of this trial?

Osteoporosis is a disease that weakens bones so the bones may break easily. The risk for osteoporosis increases with age in both women and men. Osteoporosis affects 10 million older adults in the US. Osteoporosis is a common cause of broken bones in the hips and legs. Broken bones can lead to disability, nursing home placement, and death. Because of the dire consequences, a broken hip or leg is one of the most dreaded injuries for older adults. Many studies confirm that a simple regimen of exercise, healthy diet and bone-strengthening medications can improve overall recovery after a broken hip or leg. This regimen can prevent a person from becoming disabled, having future fractures, and even prevent death. Many older adults have surgery in a hospital after breaking a hip or leg. Then older adults go to a skilled nursing facility (SNF) for rehabilitation. Care in SNFs varies greatly. Some patients do not receive the regimen that the investigators know is most beneficial to improve bone health and recovery. Even patients who get exercise, healthy diet, and bone-strengthening medication in the SNF, may not continue with the regimen once patients go home. Therefore, the investigators want to implement and test OsteoPorotic fracTure preventION System (OPTIONS). OPTIONS is a program that will integrate the regimen into the care that is provided in SNFs and after discharge to the community. OPTONS will provide information about exercise, diet, and bone-strengthening medication. OPTIONS will provide doctors, clinical staff, patients, and care partners with the information these stakeholders need to carry out the best-practice regimen. The investigators are partnering with PointClickCare, a large cloud-based healthcare software provider, with SNFs and community care sites across the US. The investigators will include 32 SNFs from different US areas. The investigators will flip a coin to assign SNFs to the intervention (OPTIONS) or the control arm (enhanced usual care) of the study. Enhanced usual care is the care that is typically provided in SNFs after a fracture and adding information about a publicly available fall prevention toolkit. The investigators are using an "implementation science" approach that requires the investigators to get input from the OPTIONS study's vast stakeholder community throughout the study. The OPTIONS study's stakeholders include patients, care partners, clinicians, and professional organizations. The research question is, can using OPTIONS in SNFs and in the community after discharge improve physical function and quality of life in older people in the year after a hip or leg fracture? The investigators are measuring patient-reported outcomes. The investigators will include 1553 patients across the 32 facilities. The investigators have selected outcomes that are important to patients. Specifically, the investigators are measuring patient-reported function and quality of life. The investigators are also measuring patient-reported falls and fractures. The investigators will track the number of patients who die during the study. This study's hypothesis is that patients who receive OPTIONS will report better physical function (i.e., can walk and take better care of themselves) than those who receive enhanced usual care. The investigators also hypothesize that patients that receive OPTIONS will report a better quality of life than those who receive enhanced usual care. This study will provide sound data about the effectiveness of OPTIONS. OPTIONS could then be spread to other SNFs and community-based programs. This would ensure that all older people receive the right care after a hip or leg fracture.

Research Team

DO

Denise Orwig, PhD

Principal Investigator

University of Maryland, Baltimore

PD

Patricia Dykes, RN, PhD

Principal Investigator

Brigham and Women's Hospital

Eligibility Criteria

This trial is for older adults who have osteoporosis and have suffered a broken hip or leg. It aims to improve their recovery by testing a program called OPTIONS, which integrates exercise, diet, and bone-strengthening medication into post-fracture care in skilled nursing facilities (SNFs) and after discharge.

Inclusion Criteria

Admitted to a participating SNF
Expected to be discharged back to the community
I am 65 years old or older.

Exclusion Criteria

Do not have access to a working phone
Not in hospice care or no terminal condition (not expected to live at least 4 months)
No severe cognitive impairment (Minimum Data Set 3.0 Cognitive Function Scale (MDS-COGS) score < 5: 0, 1 represents cognitively intact-mild impairment, 2, 3, 4 represents mild-moderate impairment, 5, 6, 7, 8 represents moderate-severe impairment)
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Treatment Details

Interventions

  • Enhanced usual care
  • OsteoPorotic FracTure PreventION System (OPTIONS)
Trial OverviewThe study compares the effectiveness of the OPTIONS program with enhanced usual care in SNFs. Enhanced usual care includes standard post-fracture treatment plus information on fall prevention. The goal is to see if OPTIONS can improve physical function and quality of life after discharge.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: OPTIONS interventionExperimental Treatment1 Intervention
OPTIONS is a multimodal intervention approach that includes providing clinical decision support (CDS) for healthcare providers, patients, and their caregivers focused on exercise, nutrition, and bone-enhancing medications using CDS in SNFs that use the same electronic health record system (PointClickCare).
Group II: Enhanced Usual CareActive Control1 Intervention
Enhanced usual care includes access to the STEADI (Stopping Elderly Accidents, Deaths, and Injuries) toolkit, a fall prevention program from the CDC.

Find a Clinic Near You

Who Is Running the Clinical Trial?

Brigham and Women's Hospital

Lead Sponsor

Trials
1,694
Recruited
14,790,000+

Hebrew SeniorLife

Collaborator

Trials
52
Recruited
273,000+

University of Maryland, Baltimore

Collaborator

Trials
729
Recruited
540,000+

University of Florida

Collaborator

Trials
1,428
Recruited
987,000+

Patient-Centered Outcomes Research Institute

Collaborator

Trials
592
Recruited
27,110,000+