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Radiotherapy + Radiopharmaceutical Therapy for Thyroid Cancer
Study Summary
This trial is testing a new way to treat thyroid cancer by combining two types of radiation. The goal is to see if it's safe and effective, and if it can deliver a high enough dose of radiation to the tumor.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I have recovered from my last chemotherapy with mild or no side effects.I am able to care for myself but cannot do normal activities or work.My thyroid cancer has spread to my neck and/or other parts of my body and cannot be fully removed by surgery.My thyroid cancer didn't fully respond to surgery or iodine treatment.My cancer absorbs iodine but hasn't responded well to radioiodine treatment.I have advanced brain metastases or critical lesions in my hip or spine that make certain treatments risky.I have not been exposed to iodinated contrast in the last 6 weeks.I have no health issues that prevent me from receiving radioiodine or external beam radiotherapy.I have a known heart condition.You are expected to live for at least 8 more weeks.I am between 18 and 85 years old.My tumor is low or intermediate risk and doesn't qualify for specific radiation treatments.My kidney and blood cell counts are within the normal range.
- Group 1: High-risk thyroid cancer patients
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are applications being accepted currently for this medical experiment?
"This medical study is actively recruiting, as indicated on clinicaltrials.gov. It was initially posted back in March 2021 and the information has been updated most recently at the end of October this year."
What other research trials have been conducted on this therapeutic approach?
"Presently, 19 clinical trials concerning this particular treatment are in progress. Of these studies, 4 have reached the third phase of research. Most of the sites conducting this trial can be found in Sevilla and Vizcaya; altogether, 66 different locations are participating."
To what extent has recruitment been successful for this medical experiment?
"Affirmative. According to the clinicaltrials.gov listing, this medical trial is currently in search of participants. It was initially shared on March 17th 2021 and has been updated as recently as October 25th 2022, with a requirement for 48 patients from one site."
What are the eligibility criteria for participation in this study?
"This clinical trial seeks 48 individuals aged 18 or older and not exceeding 85 years of age with a thyroid disorder. In order to be eligible, applicants must satisfy the following conditions: diagnoseable cancer that is not completely removable via surgery yet has infiltrated cervical soft tissues, non-recruitable distant metastases., currently pregnant or breastfeeding, life expectancy 8 weeks minimum, recovery from effects of prior chemotherapy based on organ function as per CTCAE v5.0 grade 2 standards and no previously identified cardiac complications since 131I NaI may cause such issues."
Has the Food and Drug Administration sanctioned this method of care?
"Taking into account the limited safety and efficacy data, our team's assessment assigns this treatment a score of 1."
Under which circumstances is this intervention typically recommended?
"This treatment has proven to be effective in treating communicable diseases, as well as providing antiseptic protection against minor cuts, scrapes or burns and hypothyroidism."
Does your research encompass elderly patients?
"Adults aged 18-85 are suitable to participate in this research. There are also 34 trials for minors and 232 further studies specifically catering to those over the age of 65."
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