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Neurostimulation Device

TMS + taVNS for Stroke Recovery

N/A
Waitlist Available
Research Sponsored by Medical University of South Carolina
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age 18-80
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up every 5 minutes up to 20 minutes following intervention end
Awards & highlights

Study Summary

This trial investigates whether a combination of TMS and taVNS is more effective than either modality alone in motor cortex excitability.

Who is the study for?
This trial is for adults aged 18-80 in good health who have had a stroke and are looking to improve their motor skills. It's not suitable for those with seizure disorders, pregnant women, people with metal implants above the neck, or individuals taking certain medications like psychotropics or seizure reducers.Check my eligibility
What is being tested?
The study tests if using Transcranial Magnetic Stimulation (TMS) together with transcutaneous auricular vagus nerve stimulation (taVNS) can better enhance motor cortex excitability in stroke recovery than using each method separately.See study design
What are the potential side effects?
Possible side effects may include discomfort at the stimulation site, mild headaches, lightheadedness, or temporary hearing changes due to taVNS. TMS might cause scalp discomfort during application and has a rare risk of inducing seizures.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 18 and 80 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~every 5 minutes up to 20 minutes following intervention end
This trial's timeline: 3 weeks for screening, Varies for treatment, and every 5 minutes up to 20 minutes following intervention end for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Interventional procedure

Trial Design

4Treatment groups
Active Control
Placebo Group
Group I: Active taVNS, Active TMSActive Control2 Interventions
Group II: Sham taVNS, Sham TMSPlacebo Group2 Interventions
Group III: Active taVNS, Sham TMSPlacebo Group2 Interventions
Group IV: Sham taVNS, Active TMSPlacebo Group2 Interventions

Find a Location

Who is running the clinical trial?

Medical University of South CarolinaLead Sponsor
928 Previous Clinical Trials
7,393,577 Total Patients Enrolled
67 Trials studying Stroke
60,011 Patients Enrolled for Stroke
National Institutes of Health (NIH)NIH
2,678 Previous Clinical Trials
6,909,756 Total Patients Enrolled
38 Trials studying Stroke
7,760 Patients Enrolled for Stroke

Media Library

Transcranial Magnetic Stimulation (Neurostimulation Device) Clinical Trial Eligibility Overview. Trial Name: NCT04130646 — N/A
Stroke Research Study Groups: Sham taVNS, Sham TMS, Active taVNS, Sham TMS, Sham taVNS, Active TMS, Active taVNS, Active TMS
Stroke Clinical Trial 2023: Transcranial Magnetic Stimulation Highlights & Side Effects. Trial Name: NCT04130646 — N/A
Transcranial Magnetic Stimulation (Neurostimulation Device) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04130646 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are individuals who have not yet reached their seventy-fifth year of age suitable participants in this research?

"To be eligble for this trial, individuals must fall between 18 and 65 years of age. For those under 18 or over 65, there are separate trials available; 43 for the former group and 1014 for the latter cohort."

Answered by AI

Is enrollment for this research project still open?

"Data hosted on clinicaltrials.gov indicates that, while this specific study is not actively recruiting participants at the moment – it was originally posted on March 15th 2020 and most recently updated November 4th 2022 – 1056 other trials are currently welcoming new patients."

Answered by AI

Am I eligible to partake in this research endeavor?

"Those eligible to join this trial must have suffered a stroke and be within the 18 - 65 year age bracket. At present, 40 participants are required for this study."

Answered by AI
~1 spots leftby May 2024