Study Summary
This trial is testing whether lower doses of the drug Dexmedetomidine can achieve the same effect as a higher dose of the drug, when used in combination with Sevoflurane, in children aged 1-3 years old.
Treatment Effectiveness
Effectiveness Progress
Study Objectives
1 Primary · 0 Secondary · Reporting Duration: Immediately following skin incision
Trial Safety
Safety Progress
Trial Design
9 Treatment Groups
Dexmedetomidine 0.5 mcg/kg 1-6 months
1 of 9
Dexmedetomidine 1 mcg/kg 6-12 months
1 of 9
Dexmedetomidine 1 mcg/kg 1-3 years
1 of 9
Dexmedetomidine 0.5 mcg/kg 6-12 months
1 of 9
Dexmedetomidine 1 mcg/kg 1-6 months
1 of 9
Dexmedetomidine 0.5 mcg/kg 1-3 years
1 of 9
Placebo 1-6 months
1 of 9
Placebo 6-12 months
1 of 9
Placebo 1-3 years
1 of 9
Active Control
Non-Treatment Group
180 Total Participants · 9 Treatment Groups
Primary Treatment: Dexmedetomidine 0.5 mcg/kg 1-6 months · Has Placebo Group · Phase 4
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 1 - 36 · All Participants · 1 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Frequently Asked Questions
Could you provide a list of recent trials assessing the efficacy of Dexmedetomidine 0.5 mcg/kg over 1-6 months?
"Currently, 110 clinical trials encompassing Dexmedetomidine 0.5 mcg/kg 1-6 months are underway with 23 of those in the third phase. While mainly based out of Karachi, Sindh, 207 medical centres globally have research for this medication ongoing." - Anonymous Online Contributor
Are there any age restrictions for recruitment in this clinical trial?
"This research is open to all participants between 1 and 36 months of age." - Anonymous Online Contributor
Does my medical profile qualify me to take part in the experiment?
"Requirements for entry into this clinical trial are anesthesia, pediatric age range between 1 month and 36 months. Approximately 180 individuals must be recruited to participate in the experiment." - Anonymous Online Contributor
What is the standard use of Dexmedetomidine 0.5 mcg/kg 1-6 months?
"Dexmedetomidine 0.5 mcg/kg 1-6 months is a widely used therapy to treat this disease as well as additional ailments such as ventilations, mechanical, cyclic vomiting syndrome and intubations." - Anonymous Online Contributor
To what extent is enrollment in this clinical trial being pursued?
"Correct. According to the information hosted on clinicaltrials.gov, this trial is presently seeking participants and was first posted on February 18th 2018. To complete this study, 180 patients need to be enrolled from a single medical centre." - Anonymous Online Contributor
Are there any vacancies currently available for participants of this clinical trial?
"Affirmative. Clinicaltrials.gov has records of this clinical trial beginning its recruitment process on February 18th 2018 and was last updated March 29th 2022, with the aim to recruit 180 patients from one location." - Anonymous Online Contributor
What potential risks does Dexmedetomidine 0.5 mcg/kg 1-6 months pose to individuals?
"The safety rating of Dexmedetomidine 0.5 mcg/kg 1-6 months was determined to be 3, since this is a Phase 4 trial and the associated medication has been approved." - Anonymous Online Contributor