Exercise Intervention for Blood Cancers

N/A

Recruiting

Led By Rusha Bhandari

Research Sponsored by City of Hope Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Ability to tolerate the prescribed resistance exercise program

History of childhood cancer

Must not have

Be younger than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Upup to 6 weeks

Awards & highlights

No Placebo-Only Group

Study Summary

This trial is testing the effect of exercise and nicotinamide riboside (a supplement similar to vitamin B3) on muscle health and insulin resistance in adult survivors of childhood cancer. The results may help develop regimens to improve these outcomes in future survivors.

Eligible Conditions

Blood Cancers
Cancer
Prediabetes

Eligibility Criteria

Inclusion Criteria

You will be eligible if you check “Yes” for the criteria below

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You are physically able to complete the exercise program as directed.

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You had cancer when you were a child.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 6 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 6 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 6 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Malignant Neoplasms

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Arm II (home exercise, nicotinamide riboside)Experimental Treatment2 Interventions

Patients complete home exercise as in Arm I. Patients also receive nicotinamide riboside PO daily for 6 weeks.

Group II: Arm I (home exercise)Active Control1 Intervention

Patients complete 18 home exercise sessions over 30 minutes each, 3 days per weeks for 6 weeks.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Nicotinamide Riboside

2022

Completed Phase 4

~170

0 / 2Eligibility criteria met

Find a site

Who is running the clinical trial?

City of Hope Medical CenterLead Sponsor

544 Previous Clinical Trials

2,251,959 Total Patients Enrolled

National Cancer Institute (NCI)NIH

13,402 Previous Clinical Trials

41,225,321 Total Patients Enrolled

1 Trials studying Blood Cancers

70 Patients Enrolled for Blood Cancers

Rusha BhandariPrincipal Investigator

City of Hope Medical Center

Media Library

Blood Cancers Research Study Groups: Arm I (home exercise), Arm II (home exercise, nicotinamide riboside)

Blood Cancers Clinical Trial 2023: Exercise Intervention Highlights & Side Effects. Trial Name: NCT05023993 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many individuals has the study recruited thus far?

"Yes, current information on clinicaltrials.gov confirms the active recruitment of participants for this project which was first posted on June 23rd 2022. The last update was done at the end of that month with a goal to enroll 20 patients from one site."

Answered by AI

Are recruitment efforts ongoing for this research project?

"As per the clinicaltrials.gov listing, this investigation is currently recruiting patients. This trial was first made public on June 23rd 2022 and its details have since been updated as recently as June 30th 2022."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

The Effect of Exercise and Nicotinamide Riboside Muscle Health and Insulin Resistance in Survivors of Childhood Cancer

2022. "The Effect of Exercise and Nicotinamide Riboside Muscle Health and Insulin Resistance in Survivors of Childhood Cancer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05023993.