This trial is evaluating whether Exercise Intervention will improve 1 primary outcome in patients with Impaired Glucose Tolerance. Measurement will happen over the course of Up to 6 weeks.
This trial requires 20 total participants across 2 different treatment groups
This trial involves 2 different treatments. Exercise Intervention is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"We calculated that every 3 years, over 1 million US people develop prediabetes. Many are prediabetic for many years without medical detection. A substantial proportion of persons with prediabetes later develop type 2 diabetes." - Anonymous Online Contributor
"It is still controversial whether the prediabetic state increases the risk of diabetes. Some studies show that prediabetic is associated with an increased risk of diabetes. Other observational studies have shown a protective effect of prediabetic status on future diabetes. However, meta-analyses of observational studies did not show an association between prediabetic states and the risk of diabetes." - Anonymous Online Contributor
"In summary, prediabetic subjects lack a healthy lifestyle. They have an increased body mass index (BMI), are more likely to display a sedentary (rather than an active) lifestyle, show signs of impaired sleep hygiene (hypersomnia and insomnia), have higher blood pressure, and have a higher incidence of hyperglycaemia, dyslipidaemia and hyperglycaemia. There is also a correlation between BMI and hyperglycaemia (P < 0.01)." - Anonymous Online Contributor
"Results from a recent clinical trial of the experiment have demonstrated the curative efficacy of the combination of GGT elevation and an intensive intervention to prevent HPLD." - Anonymous Online Contributor
"Diabetes was present in only one out of three subjects with prediabetes. Type 2 diabetes was more common in participants with prediabetes than in controls. Subjects with prediabetes showed significantly decreased fasting or post-challenge plasma glucose concentrations, relative to controls. The data suggest that prediabetic subjects may have a lower risk of developing overt diabetes than normal subjects." - Anonymous Online Contributor
"While the benefits of lifestyle changes to prevent prediabetics and their families are well acknowledged, more data are needed to help direct specific treatment strategies and interventions in prediabetics and their families. Obesity remains a health problem and lifestyle modification alone is insufficient to prevent, reduce, or treat obesity. There are currently limited data on the use of medication in prediabetics because of the limited number of people available for treatment of prediabetes at their clinics." - Anonymous Online Contributor
"Results from a recent paper strongly support exercise training as an effective therapeutic modality to help improve glucose control in patients with T2DM without substantial improvement in aerobic fitness. To obtain additional insights, further research of this type targeting the genetic predisposition of the patient is also essential." - Anonymous Online Contributor
"Prediabetic state is a multifactorial condition in which a complex interplay of genetic, epigenetic, nutritional, and environmental factors govern susceptibility to and progression from prediabetes to metabolic disease. The primary causes of prediabetes differ somewhat with gender. Dietary factors, such as adherence to a Mediterranean diet, are associated with a decreased risk of developing prediabetes among women, but not among men." - Anonymous Online Contributor
"While more research into the effects of exercise needs to be conducted, research shows that exercise training can help to lower blood glucose, and that the reduction in glucose and the improvement in insulin sensitivity can help individuals to be in a healthier state. A healthy individual can help by participating in an exercise program, and in these cases, exercise training (including endurance training and strength training) have shown to be more effective to take advantage of the benefits of exercise than a passive movement (such as yoga), regardless of the duration of the program." - Anonymous Online Contributor
"Results from a recent clinical trial of this study indicate that patients in moderate-severe pain, on a prediabetic state, who participate in a home-based PA program have improved QoL as compared to patients who continue on their usual prediabetic state. Results from a recent clinical trial is the first to evaluate the change in QoL in patients who are in a prediabetic state, exercising and experiencing moderate-severe pain, and who have been receiving ongoing medical treatment for weight loss. Exercise has been found to improve QoL by improving physical function." - Anonymous Online Contributor
"A total of 35.5% of exercise intervention study participants reported one or more side effects from exercise intervention. Some side effects of exercise intervention were minor, and were not significantly different from controls in terms of severity and duration." - Anonymous Online Contributor
"Genetic factors may explain only a small part of the variation in prediabetes incidence in the Framingham Offspring Study cohort. The familial nature of this condition appears to not run in families." - Anonymous Online Contributor