Stem Cell Therapy for Long COVID Syndrome
(COVID-19 Trial)
Trial Summary
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the study team to understand any specific requirements.
What data supports the effectiveness of the treatment Stem Cell Therapy for Long COVID Syndrome?
Research shows that mesenchymal stem cell therapy has been studied for severe COVID-19 patients, with follow-up results indicating potential benefits. Additionally, adipose-derived mesenchymal stem cells have been evaluated for improving symptoms in post-COVID-19 syndrome, suggesting possible effectiveness for long COVID.12345
Is stem cell therapy safe for humans?
How is stem cell treatment different for Long COVID?
Stem cell treatment for Long COVID is unique because it uses mesenchymal stem cells (MSCs) to repair damaged tissues and modulate the immune system, which is different from other treatments that may not address tissue repair or immune regulation. This approach is particularly promising for conditions like Long COVID, where persistent symptoms may result from immune dysregulation and tissue damage.1491011
What is the purpose of this trial?
The purpose of this research study is to test the safety and benefit of a human cord blood derived stem cell infusion as a treatment for individuals with post COVID-19 neurological problems. Participants in the study will have 6 clinic visits over a 12 to 14 mo. period with each visit lasting 2 to 6 hours. Participants will receive 1 stem cell infusion at study visit #3. Participants will have a brain PET and MRI scan at the baseline and 6mo. post-infusion visits. Follow-up safety assessments will be conducted at 6mo. and 1yr. after the stem cell infusion.
Research Team
Charles S. Cox, MD
Principal Investigator
The Univ. of Tx. Health Science Center- Houston
Eligibility Criteria
This trial is for adults aged 18-55 who have had COVID-19 and are now experiencing long-term neurological symptoms like anxiety, depression, pain, sleep issues, or 'brain fog'. They must be able to consent and communicate in English or Spanish. People with severe psychiatric conditions, recent infections, kidney/liver disease, cancer, immunosuppression including HIV+, substance dependencies that affect participation, significant lung disease requiring oxygen supplementation or medication use cannot join. Also excluded are pregnant women not using birth control and those unable to undergo required tests.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Participants undergo baseline brain PET and MRI scans
Treatment
Participants receive one stem cell infusion at study visit #3
Follow-up
Participants are monitored for safety and effectiveness after treatment, including brain PET and MRI scans at 6 months post-infusion
Treatment Details
Interventions
- Stem Cell
Find a Clinic Near You
Who Is Running the Clinical Trial?
Charles Cox
Lead Sponsor
CBR Systems, Inc.
Collaborator