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Behavioural Intervention

Comprehensive Rehabilitation for Orthostatic Hypotension

N/A

Waitlist Available

Led By Timothy Dillingham, MD, MS

Research Sponsored by University of Pennsylvania

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Cognitive impairment

18 years if age or older

Timeline

Screening 3 weeks

Treatment Varies

Follow Up at week 1 and week 8

Awards & highlights

Study Summary

This trial aims to develop a six-week rehabilitation program for individuals with persistent symptoms after contracting SARS CoV-2, also known as PASC. The program will include various therapies such as stretching,

Who is the study for?

This trial is for adults over 18 who previously tested positive for COVID-19 and are still experiencing symptoms like cognitive impairment or fatigue that can't be explained by other conditions. Participants must speak English or Spanish.Check my eligibility

What is being tested?

The study tests a six-week comprehensive rehabilitation program against usual care to improve functioning in individuals with Long COVID Syndrome. The program includes exercises, breathing muscle strengthening, conditioning, and tailored cognitive therapy.See study design

What are the potential side effects?

Since the intervention involves physical rehabilitation and cognitive therapy, potential side effects may include muscle soreness, fatigue during exercise, dizziness from vestibular activities, and emotional distress.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have difficulty with memory or thinking clearly.

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I am 18 years old or older.

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I have symptoms that other conditions don't explain.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ at week 1 and week 8

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~at week 1 and week 8

This trial's timeline: 3 weeks for screening, Varies for treatment, and at week 1 and week 8 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Six minute walk test

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Comprehensive RehabilitationExperimental Treatment1 Intervention

Subjects will be given the option to undergo the comprehensive rehabilitation program including speech therapy and physical therapy. Progression through the rehabilitation program will be personalized and designed based on impairments identified during the comprehensive baseline assessment and previous sessions. Subjects will undergo 12 one- hour sessions over the course of six weeks. The exercise program will be graded and targeted to the person's physical capacity with the goal of slowly advancing the exercise duration or intensity to effect physiological strengthening and increased physical function.

Group II: Augmented Usual CareActive Control1 Intervention

Following randomization, subjects in the augmented usual care group will be given the results of their in-person baseline assessment as well as the WHO Guide "Support for Rehabilitation Self-Management after COVID-19 Related Illness." This guide consists of ways to manage: breathlessness, difficulty with voice, eating, drinking and swallowing; problems with attention, memory and thinking clearly; limitations in activities of daily living, manage stress and mood dysfunction and advice for when to contact healthcare professionals. Follow-up interviews will assess process measures, including use of outpatient rehabilitation clinics, to examine possible contamination effects

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of PennsylvaniaLead Sponsor

2,002 Previous Clinical Trials

42,880,653 Total Patients Enrolled

Medical College of WisconsinOTHER

609 Previous Clinical Trials

1,162,367 Total Patients Enrolled

National Institutes of Health (NIH)NIH

2,697 Previous Clinical Trials

6,952,598 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this clinical trial currently accepting new participants?

"As per the information available on clinicaltrials.gov, this particular study is not currently accepting new patients. The trial was initially posted on November 15th, 2023 and was last edited on January 8th, 2024. However, it is important to note that there are currently a total of 2906 other ongoing trials actively seeking participants at this time."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Evaluating a Comprehensive Multimodal Outpatient Rehabilitation Program for PASC Program to Improve Functioning of Persons Suffering From Post-COVID-19 Syndrome: A Randomized Controlled Trial

2023. "Evaluating a Comprehensive Multimodal Outpatient Rehabilitation Program for PASC Program to Improve Functioning of Persons Suffering From Post-COVID-19 Syndrome: A Randomized Controlled Trial". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06156202.

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