Nasal Antiseptic for Fungal Infections
Trial Summary
What is the purpose of this trial?
This is a randomized, controlled, open-label trial of effect of 10% povidone iodine intranasal antisepsis on the detection of Candida auris.
Do I need to stop my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the treatment Povidone Iodine for fungal infections?
Is Povidone Iodine safe for use in humans?
How is the drug Povidone Iodine unique for treating fungal infections?
Povidone Iodine (PVP-I) is unique for treating fungal infections because it is a well-known antiseptic with no reported fungal resistance, and it can be used in a low-dose formulation that has shown effectiveness in cases resistant to other treatments. Additionally, it is more tolerated and effective against certain bacteria compared to other antiseptics, making it a versatile option for various infections.234511
Research Team
Mary K. Hayden, MD
Principal Investigator
Rush University Medical Center
Eligibility Criteria
Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive intranasal povidone iodine or no treatment for up to 5 days
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Povidone Iodine
Povidone Iodine is already approved in European Union, United States, Canada, Japan, China, Switzerland for the following indications:
- Skin disinfection before and after surgery
- Topical disinfection
- Eye conditions
- Topical disinfection
- Skin disinfection before and after surgery
- Eye conditions
- Topical disinfection
- Skin disinfection before and after surgery
- Topical disinfection
- Skin disinfection before and after surgery
- Topical disinfection
- Skin disinfection before and after surgery
- Topical disinfection
- Skin disinfection before and after surgery
Find a Clinic Near You
Who Is Running the Clinical Trial?
Mary K Hayden
Lead Sponsor
Rush University Medical Center
Collaborator
RML Specialty Hospital
Collaborator