Metabolic Rate Testing for Weight Loss in Bariatric Surgery Candidates

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Baylor Research Institute

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

50 Participants Needed

Trial Summary

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications.

What data supports the effectiveness of the treatment ReeVue Indirect Calorimeter for weight loss in bariatric surgery candidates?

The ReeVue Indirect Calorimeter measures resting energy expenditure (REE), which is important for understanding energy balance and weight loss. Studies show that after bariatric surgery, there are changes in energy expenditure, which can help maintain weight loss. This suggests that using the ReeVue to monitor REE could support effective weight management in bariatric surgery patients. ^{1 2 3 4 5}

Is metabolic rate testing using the ReeVue Indirect Calorimeter safe for humans?

The research articles provided do not contain specific safety data for the ReeVue Indirect Calorimeter or similar metabolic rate testing methods in humans. ^{1 3 4 6 7}

How does metabolic rate testing differ from other treatments for weight loss in bariatric surgery candidates?

Metabolic rate testing is unique because it focuses on measuring and understanding the body's energy expenditure and metabolism, which can help tailor weight loss strategies more effectively for bariatric surgery candidates. Unlike other treatments that may focus solely on diet or surgery, this approach provides insights into how the body burns calories, potentially leading to more personalized and effective weight management plans. ^{1 2 3 6 8}

What is the purpose of this trial?

This trial checks if knowing a person's resting calorie burn can help predict successful weight loss after surgery for weight loss and guide the choice of the best type of surgery.

Eligibility Criteria

This trial is for adults of any age who are scheduled to have their first bariatric surgery. It aims to include a broad range of participants without an upper age limit, focusing on those interested in understanding how their body's calorie burning at rest might influence weight loss after surgery.

Inclusion Criteria

I am scheduled for my first weight loss surgery.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Pre-operative Testing

Participants undergo pre-operative metabolic testing using a portable calorimeter

1 week

Surgery

Participants undergo primary bariatric surgery

1 week

Post-operative Testing

Participants undergo post-operative metabolic testing at 6 months and 1 year after surgery

1 year

Follow-up

Participants are monitored for weight loss and changes in resting metabolic rate

5 years

Treatment Details

Interventions

• ReeVue Indirect Calorimeter

Trial Overview The study is testing the use of a ReeVue Indirect Calorimeter, which measures resting metabolic rate—the calories burned while the body is at rest—to see if this can predict successful weight loss following bariatric surgery.

Participant Groups

Group I: Resting Metabolic Rate Testing Experimental Treatment 1 Intervention

All subjects will have the resting metabolic rate test. The ReeVue Indirect Calorimeter from Korr Medical will be used to obtain the resting metabolic rate.

Who Is Running the Clinical Trial?

Baylor Research Institute

Lead Sponsor

Trials

210

Recruited

205,000+

References

1. United States pubmed.ncbi.nlm.nih.gov

Metabolic adaptation following massive weight loss is related to the degree of energy imbalance and changes in circulating leptin. [2022]

2. United States pubmed.ncbi.nlm.nih.gov

Influence of Energy Balance on the Rate of Weight Loss Throughout One Year of Roux-en-Y Gastric Bypass: a Doubly Labeled Water Study. [2020]

3. United States pubmed.ncbi.nlm.nih.gov

Resting energy expenditure and energetic cost of feeding are augmented after Roux-en-Y gastric bypass in obese mice. [2012]

4. United States pubmed.ncbi.nlm.nih.gov

Evaluation of Resting Energy Expenditure in Subjects with Severe Obesity and Its Evolution After Bariatric Surgery. [2022]

5. United States pubmed.ncbi.nlm.nih.gov

Estimates of Resting Energy Expenditure and Total Energy Expenditure Using Predictive Equations for Individuals After Bariatric Surgery: a Systematic Review with Meta-analysis. [2023]

6. United States pubmed.ncbi.nlm.nih.gov

Bioimpedance for severe obesity: comparing research methods for total body water and resting energy expenditure. [2008]

7. United States pubmed.ncbi.nlm.nih.gov

Metabolic Implications of Obesity, Weight Loss and Energy Expenditure following Gastric Restrictive Surgery. [2019]

8. United States pubmed.ncbi.nlm.nih.gov

Twenty-four-hour energy and nutrient balance in weight stable postobese patients after biliopancreatic diversion. [2019]