Autologous Stem Cell Infusion for Neuroblastoma

Phase-Based Progress Estimates
NeuroblastomaAutologous Stem Cell Infusion - Biological
< 65
All Sexes
What conditions do you have?

Study Summary

This trial is testing a new treatment for neuroblastoma that involves two courses of chemotherapy followed by stem cell rescue.

Treatment Effectiveness

Study Objectives

1 Primary · 3 Secondary · Reporting Duration: 3 years from first PBSC infusion

Year 3
Overall Survival
Progression Free Survival
Day 42
Time to Engraftment

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Trial Design

1 Treatment Group

Patients Treated for Neuroblastoma
1 of 1

Experimental Treatment

12 Total Participants · 1 Treatment Group

Primary Treatment: Autologous Stem Cell Infusion · No Placebo Group · Phase 2

Patients Treated for NeuroblastomaExperimental Group · 7 Interventions: Thiotepa, Granulocyte colony stimulating factor, Autologous Stem Cell Infusion, Melphalan, Cyclophosphamide, Carboplatin, Etoposide · Intervention Types: Drug, Biological, Biological, Drug, Drug, Drug, Drug
First Studied
Drug Approval Stage
How many patients have taken this drug
FDA approved
FDA approved
FDA approved
FDA approved
FDA approved

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 3 years from first pbsc infusion

Who is running the clinical trial?

Masonic Cancer Center, University of MinnesotaLead Sponsor
259 Previous Clinical Trials
15,823 Total Patients Enrolled
4 Trials studying Neuroblastoma
137 Patients Enrolled for Neuroblastoma
Ashish Gupta, MBBS, MPHPrincipal InvestigatorMasonic Cancer Center, University of Minnesota
3 Previous Clinical Trials
65 Total Patients Enrolled
1 Trials studying Neuroblastoma
20 Patients Enrolled for Neuroblastoma

Eligibility Criteria

Age < 65 · All Participants · 10 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have a diagnosis of neuroblastoma before the age of 30.
You have received chemotherapy for leukemia and have recovered from that chemotherapy.