Ketorolac vs Triamcinolone Injections for Tendinopathy or Arthritis
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial is testing two types of injections, ketorolac and triamcinolone, to help patients with painful conditions in their shoulder, elbow, wrist, and hand. These injections aim to reduce inflammation and pain, improving movement and function. Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) known for its potent nonopioid pain-relieving activity, effective in treating moderate to severe pain, especially after surgery.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Is it safe to use Ketorolac and Triamcinolone injections in humans?
How do ketorolac and triamcinolone injections differ from other drugs for tendinopathy or arthritis?
Ketorolac and triamcinolone injections are unique because they offer different mechanisms of action: ketorolac is a non-steroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation, while triamcinolone is a corticosteroid that provides longer-lasting anti-inflammatory effects. This combination provides a novel approach by potentially offering both immediate and sustained relief for tendinopathy or arthritis.13467
What data supports the effectiveness of the drugs Ketorolac and Triamcinolone for tendinopathy or arthritis?
Who Is on the Research Team?
Paul A. Ghareeb, MD
Principal Investigator
Emory University
Amanda L Dempsey
Principal Investigator
Emory University
Are You a Good Fit for This Trial?
Adults with painful conditions of the hand or wrist, like trigger finger, De Quervain's tenosynovitis, or osteoarthritis in certain joints. They shouldn't have had surgery for these issues before. People under 18, those who've had similar injections recently, with allergies to the drugs used, or an active infection at the injection site can't join.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either ketorolac or triamcinolone injections for tendinopathy or arthropathy in the shoulder, elbow, wrist, or hand
Follow-up
Participants are monitored for safety and effectiveness after treatment, with assessments of pain, grip strength, and hand function
What Are the Treatments Tested in This Trial?
Interventions
- Ketorolac
- Triamcinolone
Ketorolac is already approved in United States, European Union, Switzerland for the following indications:
- Moderate to severe pain
- Postoperative pain
- Dysmenorrhea
- Idiopathic pericarditis
- Ocular itching
- Moderate to severe pain
- Postoperative pain
- Dysmenorrhea
- Ocular itching
- Inflammation after eye surgery
- Moderate to severe pain
- Moderate to severe pain
- Postoperative pain
Find a Clinic Near You
Who Is Running the Clinical Trial?
Emory University
Lead Sponsor
American Association for Hand Surgery: AAHS
Collaborator
American Association for Hand Surgery
Collaborator