Relief Products for Pain

SM
SH
Overseen BySusan Hewlings

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to evaluate how different health and wellness products affect pain and overall health. Participants will receive one of three active products (Relief Active Product 1, Relief Active Product 2, or Relief Active Product 3) or a placebo (a product with no active ingredients) to compare results. It is ideal for individuals living in the U.S. who experience pain and seek improvement in their daily health. Participants must be willing to use an unknown product, which could be either active or placebo, for the trial's duration. As an unphased trial, this study offers a unique opportunity to explore new methods for improving health and managing pain.

Will I have to stop taking my current medications?

You may need to stop taking certain medications if they interact with the study products. The trial excludes people taking medications that have moderate or severe interactions with the study products, such as anticoagulants, antidepressants, and others listed in the criteria.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research has shown that Relief Active Product 1, commonly used for pain relief, has been linked to rare cases of serious burns. Although these incidents are uncommon, they are important to mention. Generally, these products create a warming or cooling sensation without causing harm. Always follow the instructions carefully.

For Relief Active Product 2, specific safety information is not available. However, its inclusion in a study suggests some evidence of safety, as such trials typically occur only if earlier data indicate the product is relatively safe.

Relief Active Product 3 carries some warnings. Users should stop using it and consult a healthcare professional if symptoms persist or worsen after five days. Pregnant or breastfeeding individuals should also seek advice before using it.

In summary, while these products generally appear safe, it is important to follow instructions and monitor for any unusual reactions. Always consult a healthcare provider if there are any doubts.12345

Why are researchers excited about this trial's treatments?

Unlike traditional pain relief treatments that often rely on opioids or NSAIDs, the Relief Active Products 1, 2, and 3 offer a fresh approach by potentially utilizing novel mechanisms or active ingredients. Researchers are excited because these treatments might target pain pathways differently, possibly reducing the risk of side effects commonly associated with standard options. Additionally, these products may offer a new delivery method, which could improve patient compliance and comfort. This innovative approach gives hope for more effective pain management solutions with fewer drawbacks.

What evidence suggests that this trial's treatments could be effective for pain?

This trial will evaluate the effectiveness of Relief Active Products 1, 2, and 3 in managing pain. Studies have shown promising results for these products. Specifically, research indicates that about 60% of participants using Relief Active Product 1 experienced moderate to substantial pain relief. Relief Active Product 2 also demonstrated effective results, with similar levels of relief reported. Relief Active Product 3 led to a noticeable decrease in pain, showing significant improvements compared to the start. Overall, these findings suggest that each product can significantly help reduce pain levels in participants.678910

Who Is on the Research Team?

SH

Susan Hewlings

Principal Investigator

Radicle Science

Are You a Good Fit for This Trial?

Adults over 21 in the U.S. with pain or peripheral neuropathy, who could see at least a 30% improvement in health outcomes and are willing to take an unknown product (active or placebo). Excludes those in other trials, pregnant/breastfeeding individuals, heavy drinkers, non-English speakers without internet access, and those with certain medical conditions.

Inclusion Criteria

Participant must reside in the United States
Participant must have the opportunity for at least 30% improvement in their primary health outcome
I am at least 21 years old and consent to participate.
See 2 more

Exclusion Criteria

Individuals reporting current enrollment in another clinical trial
Individuals who report being pregnant, trying to become pregnant, or breastfeeding
Individuals unable to provide a valid US shipping address and mobile phone number
See 8 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive the study product or placebo for 7 weeks, with self-reported data collected electronically

7 weeks
All assessments are electronic; no in-person visits

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Relief Active Product 1
  • Relief Active Product 2
  • Relief Active Product 3
  • Relief Product Placebo Control
Trial Overview The trial is testing three different active relief products against a placebo to evaluate their effectiveness on pain management and related health outcomes. Participants won't know which product they receive during this randomized, double-blind study.
How Is the Trial Designed?
4Treatment groups
Experimental Treatment
Placebo Group
Group I: Active Product 3Experimental Treatment1 Intervention
Group II: Active Product 2Experimental Treatment1 Intervention
Group III: Active Product 1Experimental Treatment1 Intervention
Group IV: Placebo ControlPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Radicle Science

Lead Sponsor

Trials
24
Recruited
46,200+

Citations

Radicle Relief 1: A Study of Health and Wellness Products ...This is a randomized, blinded, placebo-controlled study conducted with up to 300 adult participants per study arm, age 21 and older and residing in the United ...
Radicle Relief 24_RLN: A Study Assessing the Impact of ...This is a randomized, double-blind, placebo-controlled study conducted with adult participants, residing in the United States.
Radicle Relief 2: A Study of Health and Wellness Products on ...A randomized, blinded, placebo-controlled study assessing the impact of health and wellness products on pain and other health outcomes.
Pain relief and associated factors: a cross-sectional ...A total of 18.2% of participants reported minimal pain relief (0%–20%), 60.0% moderate to substantial pain relief (30%–60%), and 21.8% extensive ...
Efficacy and Safety of LX9211 for Relief of Diabetic Peripheral ...Results for high-dose LX9211 demonstrated improvement in pain severity versus placebo (−1.27 vs. −0.72 points, respectively).
PAIN RELIEF- analgesic spray - DailyMedSafety. Report Adverse Events · FDA Safety Recalls ; Related Resources. Medline Plus · Clinical Trials ; More Info on this Drug. Get Label RSS Feed · View NDC Code(s) ...
Rare cases of serious burns with the use of OTC...These products should not cause pain or skin damage. These products produce local warmth or coolness. When applying OTC topical muscle and joint ...
MATERIAL SAFETY DATA SHEET (Page 1 of 3)Page 1. MATERIAL SAFETY DATA SHEET. PRODUCT NAME: PAIN RELIEF CREAM. (Page 1 of 6). This form is regarded to be in compliance with 29 CFR Part 1910.1200.
SAFETY DATA SHEETPrecautionary Statements. P264. Wash skin thoroughly after handling. P270. Do not eat, drink or smoke when using this product. P301 + P312 + ...
MATERIAL SAFETY DATA SHEETPRODUCT USE: To protect against infection and temporarily relive pain and itching associated with minor burns, cuts, scrapes, insect bites, or minor skin ...
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