← Back to Search

Device

Air Purification for Asthma

Q: Am I eligible to register for this research trial?

<p>This clinical research seeks 198 minors with <a href="https://www.withpower.com/clinical-trials/asthma">asthma</a>. To qualify, they must have experienced an exacerbation in the past year, be non-smokers and spend at least four nights a week in their home. They also cannot plan to move during the study period and need to fall between 8-17 years old.</p>

N/A

Waitlist Available

Led By Meredith C. McCormack, MD, MHS

Research Sponsored by Johns Hopkins University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Exacerbation in previous 12 months

Persistent asthma (NAEPP criteria)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline and about 12 weeks after the intervention

Awards & highlights

Study Summary

This trial will test whether reducing indoor pollution improves the respiratory health of overweight children with asthma more than that of lean children with asthma.

Who is the study for?

This trial is for children aged 8-17 living in Baltimore with persistent asthma, who are either of normal weight or overweight. They must spend most nights at home and have had an asthma exacerbation within the last year. Kids can't join if they're underweight, pregnant, smoke, have serious lung/heart conditions, or live in homes in disrepair.Check my eligibility

What is being tested?

The AIRWEIGHS study tests whether using air purifiers with HEPA filters at home can better improve respiratory health for overweight kids with asthma compared to those of normal weight. It's a randomized trial where half get real air purifiers and half get placebo ones without filters.See study design

What are the potential side effects?

Since this trial involves air purifiers rather than medication, there aren't typical drug side effects. However, there might be unexpected reactions like noise discomfort from the device or psychological effects from knowing they're part of a study.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

My condition has worsened in the last year.

Select...

I have long-term asthma.

Select...

I spend at least 4 nights a week at my home.

Select...

I am between 8 and 17 years old.

Select...

I am between 8 and 17 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline and about 12 weeks after the intervention

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline and about 12 weeks after the intervention

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and about 12 weeks after the intervention for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Maximum Symptom Days

Secondary outcome measures

Asthma Control

Asthma Symptoms

FENO

+2 more

Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: Active Air PurifierActive Control1 Intervention

Two portable air purifiers containing HEPA filters will be placed in the bedroom and room where the participant reports spending the most time. We have chosen to deploy two air purifiers because we have observed a 50% reduction in indoor PM concentrations with two air purifiers. Participants will be instructed to run the air purifiers continually. Participants will receive educational materials about environmental factors that are important for asthma health and environmental modification strategies. Participants will also receive educational materials about health benefits of maintaining a normal weight.

Group II: Placebo Air PurifierPlacebo Group1 Intervention

Homes in the control group will receive placebo air purifiers that have the internal air filters removed, but which will run normally. Participants will receive educational materials about environmental factors that are important for asthma health and environmental modification strategies, and educational materials about health benefits of maintaining a normal weight. At the end of the study, participants in the control group will receive active air purifiers. A control group is needed to ensure that reduced pollutant levels and health effects are not due to temporal trends and 'placebo effects' of being enrolled in an intervention trial. Participants will also be informed that being in the study does not prevent them from purchasing and using air cleaners during the study period.

0 / 5Eligibility criteria met

Find a Location

Who is running the clinical trial?

National Institute of Environmental Health Sciences (NIEHS)NIH

283 Previous Clinical Trials

1,232,039 Total Patients Enrolled

39 Trials studying Asthma

262,720 Patients Enrolled for Asthma

Johns Hopkins UniversityLead Sponsor

2,247 Previous Clinical Trials

14,816,620 Total Patients Enrolled

34 Trials studying Asthma

82,353 Patients Enrolled for Asthma

Meredith C. McCormack, MD, MHSPrincipal InvestigatorJohns Hopkins University, Pulmonary and Critical Care Medicine

Media Library

Active Air Purifier (Device) Clinical Trial Eligibility Overview. Trial Name: NCT02763917 — N/A

Asthma Research Study Groups: Placebo Air Purifier, Active Air Purifier

Asthma Clinical Trial 2023: Active Air Purifier Highlights & Side Effects. Trial Name: NCT02763917 — N/A

Active Air Purifier (Device) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02763917 — N/A

Asthma Patient Testimony for trial: Trial Name: NCT02763917 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are seniors eligible to participate in the research trial?

"This clinical trial only allows patients aged 8 to 17, in compliance with the pre-established criteria."

Answered by AI

Is this clinical experiment presently open to new participants?

"Clinicaltrials.gov indicates that this clinical trial is not presently open for enrollment as the last update was made on September 22nd, 2022. Despite this, there are currently 322 other research studies with active recruitment requirements."

Answered by AI

Am I eligible to register for this research trial?

"This clinical research seeks 198 minors with asthma. To qualify, they must have experienced an exacerbation in the past year, be non-smokers and spend at least four nights a week in their home. They also cannot plan to move during the study period and need to fall between 8-17 years old."

Answered by AI