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Neurocognitive testing for Childhood Brain Tumors

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Childhood Brain TumorsNeurocognitive testing - Other
Eligibility
4 - 18
All Sexes
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Study Summary

This trial will focus on three groups of brain tumor patients aged 4-18 to see if cognitive function can be predicted using imaging and cognitive testing.

Eligible Conditions
  • Childhood Brain Tumors

Treatment Effectiveness

Effectiveness Progress

1 of 3

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Study Objectives

5 Primary · 0 Secondary · Reporting Duration: Up to 27 months

Week 2
Identify reliable peri-diagnostic estimators of brain function as measured by advanced resting-state functional connectivity MRI (rsfcMRI) data
Identify reliable peri-diagnostic estimators of brain function as measured by neurocognitive testing
Identify reliable peri-diagnostic estimators of cognition as measured by advanced resting-state functional connectivity MRI (rsfcMRI) data
Identify reliable peri-diagnostic estimators of cognition as measured by neurocognitive testing
Up to 27 months
Magnetic Resonance Imaging

Trial Safety

Safety Progress

1 of 3

Similar Trials

1
[18F]RP-115 PET/MRI
1
Diagnostic (ferumoxytol-enhanced MRI)
1
MRI Brain and Cervical Spine

Trial Design

3 Treatment Groups

Cohort 2
1 of 3
Cohort 3
1 of 3
Cohort 1
1 of 3

Experimental Treatment

200 Total Participants · 3 Treatment Groups

Primary Treatment: Neurocognitive testing · No Placebo Group · N/A

Cohort 2Experimental Group · 2 Interventions: Neurocognitive testing, rsfcMRI · Intervention Types: Other, Device
Cohort 3
Device
Experimental Group · 1 Intervention: rsfcMRI · Intervention Types: Device
Cohort 1Experimental Group · 2 Interventions: Neurocognitive testing, rsfcMRI · Intervention Types: Other, Device

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: up to 27 months

Who is running the clinical trial?

Children's Discovery InstituteUNKNOWN
3 Previous Clinical Trials
230 Total Patients Enrolled
Washington University School of MedicineLead Sponsor
1,805 Previous Clinical Trials
2,278,503 Total Patients Enrolled
Josh Rubin, M.D., Ph.D.Principal InvestigatorWashington University School of Medicine
Stephanie Perkins, M.D.Principal InvestigatorWashington University School of Medicine
1 Previous Clinical Trials
80 Total Patients Enrolled

Eligibility Criteria

Age 4 - 18 · All Participants · 5 Total Inclusion Criteria

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