Exercise for Lung Cancer
Trial Summary
What is the purpose of this trial?
The purpose of this study is to examine how a multimodality (having or using a variety of methods to do something) exercise intervention may improve survival, function, and quality of life in participants with advanced lung cancer.
Will I have to stop taking my current medications?
The trial does not specify whether you need to stop taking your current medications. However, you must be on maintenance immunotherapy for at least one month and cannot be currently receiving chemotherapy.
What data supports the effectiveness of the treatment Exercise Intervention, Physical Activity Intervention, Exercise Program, Aerobic and Resistance Training for lung cancer?
Research shows that exercise can improve physical and functional capacity, quality of life, and reduce anxiety and depression in lung cancer patients. Studies indicate that structured exercise programs, including aerobic and resistance training, are beneficial for lung cancer patients, although more decisive evidence is needed for advanced stages.12345
Is exercise safe for people with lung cancer?
Research shows that exercise is generally safe for people with lung cancer, with studies focusing on its safety, feasibility, and effectiveness. However, the reporting of adverse events (unwanted effects) in exercise trials is not always consistent, so more standardized reporting is needed to fully understand safety.23678
How is the exercise intervention treatment for lung cancer different from other treatments?
The exercise intervention for lung cancer is unique because it focuses on improving physical strength and endurance through activities like aerobic and resistance training, rather than using medication or surgery. It is considered a safe and feasible addition to traditional treatments, helping to enhance quality of life and manage symptoms across all stages of lung cancer.39101112
Research Team
Tarah J Ballinger, MD
Principal Investigator
Indiana University
Eligibility Criteria
This trial is for adults over 18 with advanced lung cancer (stage III or metastatic NSCLC) who are on maintenance immunotherapy. They must have internet and equipment for virtual exercise, be stable or responding to current therapy, and not already doing regular moderate/vigorous exercise. Excluded are those with severe heart/respiratory conditions, uncontrolled psychiatric disorders, or a history of fragile bones.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo a supervised home-based exercise program three times weekly for 12 weeks
Follow-up
Participants are monitored for changes in fatigue, cardiorespiratory fitness, physical function, muscle mass, and depression scores
Long-term follow-up
Participants are monitored for long-term outcomes and adherence to the exercise program
Treatment Details
Interventions
- Exercise Intervention
Find a Clinic Near You
Who Is Running the Clinical Trial?
Indiana University
Lead Sponsor