Ibuprofen

Insomnia, Catarrh, Chronic Pain + 33 more

Treatment

13 FDA approvals

20 Active Studies for Ibuprofen

What is Ibuprofen

Ibuprofen

The Generic name of this drug

Treatment Summary

Ibuprofen is a medication used to reduce inflammation and pain. It is a type of non-steroidal anti-inflammatory drug (NSAID) and was first developed in 1960 as an alternative to aspirin. Ibuprofen was patented in 1961 and was first released to treat rheumatoid arthritis in the UK in 1969 and the US in 1974. It is available over-the-counter in the form of a racemic mixture, meaning it contains both the R- and S-enantiomers. The S-enantiomer is believed to be more effective than the R-enantiomer in treating pain and inflammation

Motrin

is the brand name

Ibuprofen Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Motrin

Ibuprofen

1974

2460

Approved as Treatment by the FDA

Ibuprofen, also called Motrin, is approved by the FDA for 13 uses including Acute Pain and Dysmenorrhea .

Acute Pain

Used to treat Pain, Acute in combination with Oxycodone

Dysmenorrhea

Mild pain

Gastric Ulcer

Used to treat Gastric Ulcer in combination with Famotidine

Rheumatoid Arthritis

Used to treat Rheumatoid Arthritis in combination with Famotidine

Stomach Ulcer

Used to treat Gastric Ulcer in combination with Famotidine

Pain, Acute

Used to treat Pain, Acute in combination with Oxycodone

Osteoarthritis (OA)

Used to treat Osteoarthritis (OA) in combination with Famotidine

Migraine

Osteoarthritis

Used to treat Osteoarthritis (OA) in combination with Famotidine

Fever

Headache

Menstrual Distress (Dysmenorrhea)

Effectiveness

How Ibuprofen Affects Patients

Ibuprofen is used to manage pain, fever, and inflammation. It works by blocking the production of prostanoids, which are substances involved in inflammation. Ibuprofen can also help with dental procedures, menstrual pain, and migraines. It may also reduce neurodegeneration and help with Parkinson's Disease and breast cancer.

How Ibuprofen works in the body

Ibuprofen works by blocking an enzyme called cyclooxygenase. This enzyme helps create substances called prostaglandins, which cause pain and fever. Ibuprofen stops the production of prostaglandins, which reduces inflammation, pain, fever, and swelling. However, blocking this enzyme can also lead to side effects like stomach ulcers.

When to interrupt dosage

The recommended dose of Ibuprofen is reliant upon the identified condition, including smooth muscle relaxation prior to radiological procedures, Catarrh and Pain relief. The quantity of dosage differs, according to the technique of delivery (e.g. Kit - Oral; Topical or Tablet) featured in the table below.

Condition

Dosage

Administration

Migraine Disorders

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Spasm

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Juvenile arthritis

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Muscle Relaxation

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Influenza

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Chronic Pain

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Migraine

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Analgesics

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Pain

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Muscle Spasticity

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Stomach Ulcer

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Nasal Congestion

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Arthritis, Gouty

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Cystic Fibrosis

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Dysmenorrhea

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Premature Birth

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Pain

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Acute Pain

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Mild pain

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Primary Dysmenorrhoea

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable - Oral, Tablet, chewable, Tablet - Oral, Tablet, Suspension / drops, Suspension / drops - Oral, Liquid, Liquid - Oral, Kit, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Injection, solution - Intravenous, Injection, solution, Injection - Intravenous, Injection, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Cream, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Warnings

Ibuprofen Contraindications

Condition

Risk Level

Notes

Coronary Artery Bypass Grafting

Do Not Combine

Pulse Frequency

Do Not Combine

There are 20 known major drug interactions with Ibuprofen.

Common Ibuprofen Drug Interactions

Drug Name

Risk Level

Description

Brigatinib

Major

The metabolism of Brigatinib can be decreased when combined with Ibuprofen.

Cabazitaxel

Major

The metabolism of Cabazitaxel can be decreased when combined with Ibuprofen.

Enasidenib

Major

The metabolism of Enasidenib can be decreased when combined with Ibuprofen.

Erlotinib

Major

The metabolism of Erlotinib can be decreased when combined with Ibuprofen.

Fluorouracil

Major

The metabolism of Fluorouracil can be decreased when combined with Ibuprofen.

Ibuprofen Toxicity & Overdose Risk

Consuming more than 99mg/kg of ibuprofen can lead to abdominal pain, nausea, vomiting, fatigue, dizziness, vertigo, drowsiness, insomnia, headache, fainting, ringing in the ears, depression of the central nervous system, seizures, and difficulty breathing. In very rare cases, it can also cause metabolic acidosis, abnormal liver function, high potassium levels, kidney failure, and coma. The reported lethal dose of ibuprofen is 636mg/kg in rats, 740mg/kg in mice, and 495mg/kg in guinea pigs.

Ibuprofen Novel Uses: Which Conditions Have a Clinical Trial Featuring Ibuprofen?

At present, there are 531 active trials examining the potential of Ibuprofen in managing Rheumatoid Arthritis, Chronic Pain and Migraine Symptoms.

Condition

Clinical Trials

Trial Phases

Premature Birth

24 Actively Recruiting

Not Applicable, Phase 2, Phase 3, Phase 4, Phase 1

Rheumatoid Arthritis

56 Actively Recruiting

Not Applicable, Phase 3, Phase 1, Phase 2, Phase 4

Influenza

0 Actively Recruiting

Pain

0 Actively Recruiting

Aquaporin 2

3 Actively Recruiting

Phase 3, Not Applicable, Phase 2

Chronic Pain

122 Actively Recruiting

Not Applicable, Phase 2, Phase 4, Phase 3, Early Phase 1, Phase 1

Migraine

47 Actively Recruiting

Phase 4, Not Applicable, Phase 1, Phase 3, Phase 2, Early Phase 1

Muscle Relaxation

0 Actively Recruiting

Juvenile arthritis

7 Actively Recruiting

Phase 2, Not Applicable, Phase 3

Migraine

13 Actively Recruiting

Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4

Acute Pain

2 Actively Recruiting

Not Applicable, Phase 1

Primary Dysmenorrhoea

2 Actively Recruiting

Not Applicable

Nasal Congestion

0 Actively Recruiting

Catarrh

0 Actively Recruiting

Pericarditis

2 Actively Recruiting

Phase 2, Phase 3

Arthritis, Gouty

0 Actively Recruiting

Insomnia

0 Actively Recruiting

Pain

0 Actively Recruiting

Cystic Fibrosis

0 Actively Recruiting

Pain

0 Actively Recruiting

Patient Q&A Section about ibuprofen

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who should not take ibuprofen?

"If you have severe heart failure, severe kidney failure or severe liver failure, are trying to get pregnant, have high blood pressure that's not under control, have heart disease or mild to moderate heart failure, or have ever had a stroke, you may not be able to use Invokana."

Answered by AI

What is ibuprofen used for?

"Ibuprofen can be bought without a prescription and is a type of painkiller known as an NSAID. It can be used to relieve mild to moderate pain, such as toothache, migraine, and period pain."

Answered by AI

How is ibuprofen harmful?

"NSAIDs may cause ulcers, bleeding, or holes in the stomach or intestine, which can develop at any time during treatment and may happen without warning symptoms. This can lead to death."

Answered by AI

What is better Tylenol or ibuprofen?

"Acetaminophen is most effective for fever, aches, and pains, but is less effective for pain caused by inflammation. Ibuprofen is more effective for pain caused by inflammation, such as menstrual cramps and arthritis."

Answered by AI

Clinical Trials for Ibuprofen

Image of University of North Carolina at Chapel Hill in Chapel Hill, United States.

Pain Medicines for Period Pain in Crohn's Disease

18 - 44
Female
Chapel Hill, NC

The purpose of this pilot study is to prepare for a larger study that will compare the effectiveness and safety of two common pain medications, ibuprofen and acetaminophen, to help treat period cramps in women with Crohn's disease. The goal of this study is to identify any challenges in running a larger study. The investigators will track how many people sign up for the study, how well participants follow the study plan, how many people stay in the study, and whether they are able to complete all the study activities, such as taking the medication, submitting samples, and filling out surveys. During the study, participants will undergo a screening visit that includes a blood draw, physical exam, pregnancy test, stool testing, and complete surveys about Crohn's disease and menstrual cycles. Once this visit is complete, the rest of the study will occur at home. Participants will be assigned to take either ibuprofen or acetaminophen to help treat period cramps for four menstrual cycles in a row. Participants will take ibuprofen for two cycles and acetaminophen for two cycles. Participants will know which medication is being taken at any given time, but the order in which they take the medications will be randomly assigned. Before each menstrual cycle, participants will submit a stool sample and fill out a short (\<1 minute) electronic survey. When participants develop period cramps, they will take the assigned medication for three days and fill out short (\<1 minute) electronic surveys about their cramps. After participants finish taking the medication for three days, they will submit another stool sample and fill out two more short (\<1 minute) electronic surveys. After have completing this process for four menstrual cycles, a remote interview with a researcher to give feedback on the study will be conducted.

Waitlist Available
Has No Placebo

University of North Carolina at Chapel Hill

Erica J Brenner, MD, MSCR

Image of AltaSciences, Inc in Cypress, United States.

SBS-147 Safety Study

18 - 55
All Sexes
Cypress, CA

This study is part of the HEAL Initiative supported by the NIH. The purpose of this study is to learn how safe the study drug, SBS-147, is and how people's bodies respond to and process it. Researchers will also look for any side effects that may occur when taking SBS-147. Some participants will receive SBS-147, and others will receive a placebo, which looks the same but does not contain any medicine. This helps researchers fairly compare results. The study includes two parts: Single-Dose Group, where Participants receive SBS-147 or placebo one time. Multiple-Dose Group, where Participants receive SBS-147 or placebo once or twice daily for 7 days.

Phase 1
Waitlist Available

AltaSciences, Inc

Jeff Reich, MD

Sparian Biosciences, Inc

Have you considered Ibuprofen clinical trials?

We made a collection of clinical trials featuring Ibuprofen, we think they might fit your search criteria.
Go to Trials
Image of Royal Alexandra Hospital in Edmonton, Canada.

Oxygen Concentration for Premature Birth

No minimum age - 10
All Sexes
Edmonton, Canada

This study is aims to examine the best amount of oxygen to give preterm babies (born between 32 and 35 weeks) right after birth. In the past, doctors used high levels of oxygen, but research has shown that using lower levels might help reduce the risk of death in full-term babies without harming brain development. However, investigators don't know the best oxygen level for babies born a little early (32 to 35 weeks). Some early data suggests that giving lower oxygen levels (FiO2 0.3) may not help babies reach healthy oxygen levels by 5 minutes after birth. This study will compare two oxygen levels-FiO2 0.6 and FiO2 0.3 to see which helps babies breathe better and need less ongoing breathing support. Researchers will study over 1,500 babies in hospitals across Alberta, Canada, to find the safest approach for these babies.

Waitlist Available
Has No Placebo

Royal Alexandra Hospital

Georg Schmolzer

Have you considered Ibuprofen clinical trials?

We made a collection of clinical trials featuring Ibuprofen, we think they might fit your search criteria.
Go to Trials

Have you considered Ibuprofen clinical trials?

We made a collection of clinical trials featuring Ibuprofen, we think they might fit your search criteria.
Go to Trials