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What is Edarbyclor
Azilsartan medoxomilThe Generic name of this drug
Treatment SummaryAzilsartan medoxomil, sold under the brand name Edarbi, is a drug used to treat high blood pressure. It works by blocking the action of angiotensin II, a hormone that causes blood vessels to narrow. It is usually prescribed as mono-therapy or in combination with other antihypertensive drugs. It may help reduce the risk of cardiovascular events like stroke and heart attack. Azilsartan medoxomil may also have potential off-label uses in patients with a history of heart failure or heart attack.
Edarbiis the brand name
Edarbyclor Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Edarbi
Azilsartan medoxomil
2011
10
Approved as Treatment by the FDA
Azilsartan medoxomil, otherwise known as Edarbi, is approved by the FDA for 2 uses including inadequate response to monotherapy and Hypertensive disease .inadequate response to monotherapy
Used to treat inadequate response to monotherapy in combination with Chlorthalidone
Hypertensive disease
Helps manage High Blood Pressure (Hypertension)
Effectiveness
How Edarbyclor Affects PatientsAzilsartan medoxomil helps to lower blood pressure by blocking the angiotensin II receptor, which helps to reduce the amount of pressure in the blood vessels. It is not affected by a person's sex, race, or any form of kidney or liver impairment. In addition, it does not affect potassium, sodium, or bradykinin levels. Studies have shown that it can significantly reduce blood pressure in just one dose. There is no evidence that it works differently in people of African descent.
How Edarbyclor works in the bodyAzilsartan medoxomil helps regulate blood pressure by blocking the effects of angiotensin II. Angiotensin II is a hormone that causes blood vessels to narrow, making blood pressure rise. Azilsartan binds to the receptor responsible for angiotensin II, blocking its effects and lowering blood pressure. It is more effective than other medications in this class because it binds more tightly to the receptor and takes longer to dissociate.
When to interrupt dosage
The recommended dosage of Edarbyclor hinges upon the diagnosed disorder, such as Hypertensive disease, Atrial Fibrillation and Albuminuria. The amount of dosage is contingent upon the delivery approach featured in the table below.Condition
Dosage
Administration
Atrial Fibrillation
40.0 mg, , 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral
Hypertensive disease
40.0 mg, , 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral
Albuminuria
40.0 mg, , 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral
inadequate response to monotherapy
40.0 mg, , 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral
Type 2 Diabetes
40.0 mg, , 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral
Warnings
Edarbyclor ContraindicationsCondition
Risk Level
Notes
Type 2 Diabetes
Do Not Combine
Anuria
Do Not Combine
Common Edarbyclor Drug Interactions
Drug Name
Risk Level
Description
Amifostine
Major
Azilsartan medoxomil may increase the hypotensive activities of Amifostine.
Lithium carbonate
Major
The serum concentration of Lithium carbonate can be increased when it is combined with Azilsartan medoxomil.
Lithium citrate
Major
The serum concentration of Lithium citrate can be increased when it is combined with Azilsartan medoxomil.
Lithium hydroxide
Major
The serum concentration of Lithium hydroxide can be increased when it is combined with Azilsartan medoxomil.
Sacubitril
Major
The risk or severity of angioedema can be increased when Azilsartan medoxomil is combined with Sacubitril.
Edarbyclor Toxicity & Overdose RiskThere is no known maximum toxic dose of azilsartan yet. In clinical trials, healthy individuals tolerated a single dose of up to 320 mg without any significant side effects. If an overdose occurs, supportive measures should be taken as azilsartan cannot be removed through dialysis. Azilsartan is also a teratogenic agent, meaning it can cause birth defects if taken during the second or third trimesters of pregnancy.
Edarbyclor Novel Uses: Which Conditions Have a Clinical Trial Featuring Edarbyclor?
At present, 265 active clinical trials are assessing the utility of Edarbyclor for Atrial Fibrillation, inadequate response to monotherapy, and Albuminuria control.Condition
Clinical Trials
Trial Phases
inadequate response to monotherapy
0 Actively Recruiting
Hypertensive disease
19 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Type 2 Diabetes
92 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4
Albuminuria
4 Actively Recruiting
Phase 3, Phase 4, Phase 2
Atrial Fibrillation
146 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3, Early Phase 1
Edarbyclor Reviews: What are patients saying about Edarbyclor?
5Patient Review
1/8/2016 I've always had low blood pressure, but I got extremely sick and my blood pressure shot up to 244/166. I went to the ER and was given a shot and a pill, then sent home. My family doctor saw me the next day and diagnosed me with stage three kidney failure. I was taking five different medications eleven times a day at that point, and it was consuming my life. But then I was put on edarbyclor and bystolic, and now my blood pressure is down to 106/64. I do have bad muscle weakness and heart problems, but overall this medication has been a lifes
5Patient Review
3/20/2019 This treatment has been a godsend for me. I've had hypertension for years and have tried every medication out there with little success. But as soon as I started taking Edarbi, my blood pressure dropped significantly. I'm now down to an average of 130/70, and it only costs me $40 a month!
5Patient Review
1/25/2022 After years of treatments that didn't work, this was a complete change for the better. It's pricey, but to me it was worth every penny. Additionally, I experienced no negative side effects. From what I can tell based on other reviews, it doesn't work for everyone. But it worked extremely well for me and I'm very grateful.
5Patient Review
5/13/2021 This medication was the only one that actually helped lower my blood pressure. In just two weeks, it went from an average of 140/100 to 110/70. I also didn't experience any negative side effects, which was great.
5Patient Review
1/26/2021 I had hypertension for 30 years that didn't respond to any treatment I tried—until this one. Within two weeks of taking it, my blood pressure dropped significantly. The only side effect was occasional dizziness when it would drop too low, but that's a small price to pay compared to the alternative of high blood pressure.
5Patient Review
2/23/2017 In an emergency situation, my doctor gave me a sample of this medication. Within 30 minutes, my blood pressure had decreased from 190/100 to 140/80. This was nothing short of miraculous for me given my history of high blood pressure, strokes, diabetes, multiple sclerosis, and allergies.
5Patient Review
7/10/2016 Since switching to Edarbyclor 40/25 mg from my previous medication (Valsartan & HTZ), my blood pressure has decreased slightly. I've also experienced some fatigue, but overall I'm pleased with the results so far.
5Patient Review
11/16/2017 Edarbyclor and Bystolic have finally helped me get my high blood pressure under control.
5Patient Review
3/23/2019 I had tried a few different treatments before this one, and none of them worked as well as this one has. In just two weeks, my blood pressure has dropped significantly.
5Patient Review
11/15/2017 No negative effects and great results.
4Patient Review
7/20/2019 I've only been taking this medication for a week, but I'm already seeing results that I like. The only downside is that my arms feel tired, but the doctor said I should expect that.
4Patient Review
3/14/2016 I had to stop taking this after just one pill because it made me feel faint and unsteady. I was also incoherent and my fingers were tingling.
4Patient Review
3/30/20151.7Patient Review
12/20/2018 I tried this for around eight months, and it just gave me a lot of terrible side effects. I would never recommend it to anyone.
1Patient Review
12/21/2017 This medication has caused me a great deal of pain and discomfort. I stopped taking it three days ago, and I'm still feeling the effects. My doctor says it's not the medication, but I find that hard to believe.
1Patient Review
1/10/2016 I took up to 100mg of Metoprolol per day, and it did nothing for me. I tried Lisinopril and Amlodapine next, but experienced only negative side effects. Finally, I started taking Edarbyclor, and my blood pressure lowered significantly within days. Give it a chance!
Patient Q&A Section about edarbyclor
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Edarbyclor hard on the kidneys?
"This medication can have harmful effects on the blood vessels of the brain, heart, and kidneys, which can lead to stroke, heart failure, or kidney failure."
Answered by AI
What side effects does Edarbyclor have?
"If you experience any of the following symptoms, you may be experiencing an electrolyte imbalance:
-Swelling
-Weight gain
-Feeling short of breath
-Dry mouth
-Extreme thirst
-Drowsiness
-Restless feeling
-Confusion
-Increased or decreased urination
-Constipation
-Muscle pain or weakness
-Fast heart rate
-Seizures or convulsions"
Answered by AI
What is Edarbyclor used to treat?
"Both EDARBI and EDARBYCLOR are used to treat hypertension, but your doctor may also prescribe additional medication to be taken alongside either of these drugs."
Answered by AI
What is the generic for Edarbyclor?
"Although there is no generic version of Edarbyclor currently available, there are ways to lower the cost of this medication. GoodRx coupons, copay cards, and patient assistance programs can help reduce the expense."
Answered by AI