Diclofenac Potassium

Contusions, Pain, Photophobia + 54 more

Treatment

10 FDA approvals

20 Active Studies for Diclofenac Potassium

What is Diclofenac Potassium

Diclofenac

The Generic name of this drug

Treatment Summary

Diclofenac is a type of anti-inflammatory medication used to reduce pain and inflammation caused by a variety of conditions. It works by blocking enzymes that produce hormones that cause inflammation and pain. It is often used as a first-line treatment for acute and chronic pain, and is sometimes taken in combination with another drug to prevent stomach ulcers. Diclofenac was first approved by the FDA in 1988 and is sold under the brand name Voltaren.

Voltaren

is the brand name

image of different drug pills on a surface

Diclofenac Potassium Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Voltaren

Diclofenac

1988

767

Approved as Treatment by the FDA

Diclofenac, also called Voltaren, is approved by the FDA for 10 uses including Osteoarthritis of the Knee and Pain .

Osteoarthritis of the Knee

Used to treat Osteoarthritis of the Knee in combination with Capsaicin

Pain

Helps manage Pain

Postoperative Inflammatory Response

Chronic Pain

Helps manage Pain

Osteoarthritis (OA)

Used to treat Osteoarthritis (OA) in combination with Misoprostol

Stomach Ulcer

Used to treat develop NSAID-induced gastric ulcers in combination with Misoprostol

Osteoarthritis of the Knee

Used to treat Osteoarthritis of the Knee in combination with Capsaicin

Osteoarthritis

Used to treat Osteoarthritis (OA) in combination with Misoprostol

Rheumatoid Arthritis

Cataract Surgery

Effectiveness

How Diclofenac Potassium Affects Patients

Diclofenac is used to reduce pain, inflammation, and fever. However, it can also increase the chances of developing a stomach ulcer because it reduces the amount of protective mucus in the stomach.

How Diclofenac Potassium works in the body

Diclofenac works by blocking the enzymes responsible for producing prostaglandin molecules. These molecules are responsible for pain and inflammation, so when they are blocked, the pain and inflammation is reduced. Diclofenac also reduces sensitivity to heat and other stimuli, as well as preventing white blood cells from flowing to sites of inflammation. It also reduces the activity of NF-Kappa B, a contributor to cancer, and stops tumor suppressor proteins from leaving the cell. Finally, it stops the activity of neurons in the hypothalamus that create a fever. All of these effects work together to reduce pain and inflammation caused

When to interrupt dosage

The suggested measure of Diclofenac Potassium is contingent upon the determined circumstance, such as Joint Pain, Postoperative Inflammatory Response and Osteoarthritis (OA). The volume of dosage can be found in the table presented below, depending on the mode of administration (e.g. Cream; Kit; Solution or Kit; Oil; Solution / drops).

Condition

Dosage

Administration

Muscle Pain

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Wounds, Nonpenetrating

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Inflammation

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Contusions

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Pain

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Photophobia

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Inflammation

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Fever

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Rheumatoid Arthritis

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Surgery, Dental

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Conjunctivitis

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Pain

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

perioperative miosis

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Pain

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Rheumatism

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Postoperative Inflammatory Response

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Sprains and Strains

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Osteoarthritis of the Knee

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Musculoskeletal System

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Postoperative

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, film coated, Tablet, film coated - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Solution - Topical, Tablet, Tablet - Oral, Kit, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Transdermal, Solution / drops - Transdermal, Patch, Patch - Topical, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Powder - Oral, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Warnings

Diclofenac Potassium Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

Heart failure

Do Not Combine

Crohn's Disease

Do Not Combine

recent history of anal bleeding

Do Not Combine

Hemorrhagic Disorders

Do Not Combine

Gastritis

Do Not Combine

inflammatory lesions of the Rectum

Do Not Combine

active Gastrointestinal Bleeding

Do Not Combine

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

active Gastrointestinal Perforation

Do Not Combine

Duodenal Ulcer

Do Not Combine

Coronary Artery Bypass Grafting

Do Not Combine

Severe Hepatic Impairment

Do Not Combine

Ulcerative Colitis

Do Not Combine

Liver Diseases

Do Not Combine

Stroke

Do Not Combine

Third trimester of pregnancy

Do Not Combine

Hematochezia

Do Not Combine

Kidney Failure

Do Not Combine

Kidney Failure

Do Not Combine

Anus

Do Not Combine

Ulcer

Do Not Combine

damaged skin

Do Not Combine

Gastric ulcer

Do Not Combine

Peptic Ulcer

Do Not Combine

Hyperkalemia

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Diclofenac may interact with Pulse Frequency

There are 20 known major drug interactions with Diclofenac Potassium.

Common Diclofenac Potassium Drug Interactions

Drug Name

Risk Level

Description

Brigatinib

Major

The metabolism of Brigatinib can be decreased when combined with Diclofenac.

Cabazitaxel

Major

The metabolism of Cabazitaxel can be decreased when combined with Diclofenac.

Cyclophosphamide

Major

The metabolism of Cyclophosphamide can be decreased when combined with Diclofenac.

Enasidenib

Major

The metabolism of Enasidenib can be decreased when combined with Diclofenac.

Erlotinib

Major

The metabolism of Erlotinib can be decreased when combined with Diclofenac.

Diclofenac Potassium Toxicity & Overdose Risk

Overdosing on Voltaren can lead to symptoms such as fatigue, nausea, vomiting, upper abdominal pain, and bleeding from the digestive tract. In rare cases, patients may experience high blood pressure, kidney damage or failure, hypoventilation, or coma. Treatments for Voltaren overdose include inducing vomiting and activated charcoal, as long as the overdose occurred within the last 4 hours.

image of a doctor in a lab doing drug, clinical research

Diclofenac Potassium Novel Uses: Which Conditions Have a Clinical Trial Featuring Diclofenac Potassium?

Currently, 491 active clinical trials are assessing the capacity of Diclofenac Potassium to mitigate Inflammation, enhance Argon Laser Trabeculoplasty and assuage Osteoarthritis of the Knee.

Condition

Clinical Trials

Trial Phases

Inflammation

57 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 3

Osteoarthritis of the Knee

77 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1

Chronic Pain

116 Actively Recruiting

Not Applicable, Phase 2, Phase 4, Phase 3, Early Phase 1, Phase 1

Rheumatoid Arthritis

56 Actively Recruiting

Not Applicable, Phase 3, Phase 1, Phase 2, Phase 4

Postoperative Pain

19 Actively Recruiting

Phase 4, Phase 2, Phase 1, Not Applicable, Phase 3

Dysmenorrhea

1 Actively Recruiting

Not Applicable

Muscle Pain

2 Actively Recruiting

Phase 4, Phase 2

Conjunctivitis

0 Actively Recruiting

Musculoskeletal System

1 Actively Recruiting

Not Applicable

corneal refractive surgery

0 Actively Recruiting

Postoperative Inflammatory Response

0 Actively Recruiting

Photophobia

5 Actively Recruiting

Not Applicable

Pain

2 Actively Recruiting

Not Applicable

Stomach Ulcer

0 Actively Recruiting

Rheumatism

0 Actively Recruiting

Juvenile arthritis

6 Actively Recruiting

Phase 2, Not Applicable, Phase 3

radial keratotomy

0 Actively Recruiting

Joints

0 Actively Recruiting

Pericarditis

2 Actively Recruiting

Phase 2, Phase 3

Acute Coryza

0 Actively Recruiting

Diclofenac Potassium Reviews: What are patients saying about Diclofenac Potassium?

5

Patient Review

3/19/2014

Diclofenac Potassium for Rheumatic Disease causing Pain & Stiffness in Backbone

I was able to get back to my normal routine within just a few days of starting this medication. Not only that, but it didn't bother my stomach like other medications have in the past.

5

Patient Review

7/17/2014

Diclofenac Potassium for Pain

This medicine was really effective in treating my lower back pain. I would have continued to take it if it weren't for the fact that it's an NSAID, and I can't take those anymore because of stomach problems.

5

Patient Review

5/27/2014

Diclofenac Potassium for Pain

This medication was a godsend after I broke two ribs. It allowed me to function normally while it was working, and the pain was unbearable when it began to wear off.

5

Patient Review

12/25/2015

Diclofenac Potassium for Gout

I was experiencing pain in my left heel and took ibuprofen 400mg and allopurinol 100mg for more than two weeks without any relief. I started taking diclofenac potassium oral 100mg and parastaimal 500mg daily, and within two days the pain was gone.

5

Patient Review

9/9/2015

Diclofenac Potassium for Pain

This medication was a godsend for my chronic pain. I felt great within a few days and was able to move around without stiffness or pain. However, now that I'm out of my prescription, the pain has come back full force and I am miserable once again.

5

Patient Review

8/29/2015

Diclofenac Potassium for Inflammation of the Sac Surrounding the Joint - Bursitis

The pain relief I experienced from this medication was nothing short of miraculous.

5

Patient Review

5/24/2021

Diclofenac Potassium for Migraine Headache

This medication is a great rescue for migraines. It takes away about 75% of the pain, which makes it much easier to get through the day. I also haven't had any problems with taking it on an empty stomach.

5

Patient Review

1/12/2016

Diclofenac Potassium for Rheumatoid Arthritis

I'm so glad I found this drug! It's been a huge help. However, I still need to take my norco.

5

Patient Review

9/19/2016

Diclofenac Potassium for Severe Lower Back Pain from Kidney Stones

This provided immediate relief, which was great.

5

Patient Review

5/26/2019

Diclofenac Potassium for Rheumatoid Arthritis

I really appreciate this medication. It's helped me a lot.

5

Patient Review

7/4/2014

Diclofenac Potassium for Painful Periods

This medication was very effective in managing my pain during menstruation.

4.3

Patient Review

3/31/2014

Diclofenac Potassium for Inflammation of the Tendon

This treatment helped with my muscle pain.

3.3

Patient Review

2/3/2014

Diclofenac Potassium for Inflammation of the Tendon

The IT Band is a common source of pain for many people.

3

Patient Review

9/10/2017

Diclofenac Potassium for Migraine Headache

It's really tough on my stomach, and the cost is outrageous.

2.7

Patient Review

7/11/2014

Diclofenac Potassium for Inflammation of the Sac Surrounding the Joint - Bursitis

I've gone from being really cold (shivering, cold hands and feet) to being excessively hot over the entire portion of my body. Its fore an inflamed tail bone which turned red and feels like a bruise someone his constantly touching.

2

Patient Review

8/15/2014

Diclofenac Potassium for Rheumatoid Arthritis

I was hospitalized after taking just five pills of this medication. I couldn't respond to the doctor's questions. He said that this medicine caused me a lot of harm and pain. I'm still suffering and now have to use a walker, which is something new for me.

2

Patient Review

1/4/2015

Diclofenac Potassium for Joint Damage causing Pain and Loss of Function

I took this medication for approximately six weeks to treat inflammation in my shoulder joints. Unfortunately, the side effects were really terrible - I was constantly moody and got my period all the time. I would not recommend this medication for women of child-bearing age. My doctor didn't mention any of these potential side effects, so I had to figure it out on my own!

1.7

Patient Review

6/30/2016

Diclofenac Potassium for Pain

I have fibro, RA, and migraines. They took my old medication away and replaced it with this one. I feel like I'm constantly hungover and all I want to do is sleep. When I called my doctor about it, they said it wasn't the medication. Hello? If it's not the medication, then what is it? Ginger tea isn't cutting it.

1.7

Patient Review

9/13/2017

Diclofenac Potassium for Pain

I was given this medication for lower back pain, but I am now experiencing stomach pain. This is not an ideal situation, so I will have to speak with my doctor about finding a different treatment option.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about diclofenac potassium

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is diclofenac a strong painkiller?

"Diclofenac is stronger than ibuprofen and should be taken every six to eight hours. Ibuprofen usually needs to be taken in high doses to relieve pain associated with arthritis."

Answered by AI

What is diclofenac potassium used for?

"This medication is known as a nonsteroidal anti-inflammatory drug (NSAID).

This medication is used to relieve various kinds of pain and swelling, including muscle aches, backaches, dental pain, menstrual cramps, and sports injuries. It also helps reduce pain, swelling, and stiffness caused by arthritis."

Answered by AI

What are the dangers of taking diclofenac?

"NSAIDs such as diclofenac can cause painful ulcers, bleeding, or holes in the stomach or intestine. These problems can develop at any time during treatment and sometimes without any warning symptoms. In rare cases, they can even be fatal."

Answered by AI

Is diclofenac potassium a painkiller?

"If you need to take an NSAID for a long period of time, your doctor or pharmacist may recommend ibuprofen or naproxen instead of diclofenac. This is because diclofenac is more likely to cause heart problems."

Answered by AI

Clinical Trials for Diclofenac Potassium

Image of Alberta Children's Hospital in Calgary, Canada.

Treatment for Fibromyalgia

< 65
All Sexes
Calgary, Canada

2.1 CONTEXT Pain and agitation are common comorbidities of pediatric critical illness due to both underlying disease processes and ICU related therapies. These are associated with both short and long term negative sequelae including increased mortality, length of stay, rates of ICU delirium, worse sleep, increased anxiety, depression, and chronic pain. The current standard of care to manage PICU associated pain and agitation is the use of analgosedation (e.g. opioids and benzodiazepines) these too are associated with increased time on the ventilator, length of stay, ICU delirium, and long term mental health and negative neuro-cognitive outcomes. Despite recommendations for increased use of non-pharmacologic therapies in the prevention and management of PICU associated pain, agitation, delirium, and analgosedation exposure, there are currently know therapies with clear evidence of efficacy. Therapeutic cuddling (e.g. kangaroo care, clothed cuddling, comfort holding, etc.) has been shown to decrease pain and anxiety in critically ill neonates, and healthy children and adults. Positive affective touch and hugging has known physiologic benefits and has been associated with decreased pain, improved immunity, and decreased mortality. Despite the potential for this intervention to aid in the prevention and management of PICU associated pain, agitation, delirium and analgosedation exposure, little data exists on efficacy of therapeutic cuddling in critically ill children. 2.2 OBJECTIVES 2.2.1 Primary Determine the feasibility of screening, consent, randomization, and retention of participants in a pragmatic RCT of therapeutic cuddling versus standard of care in the Alberta Children's Hospital Pediatric Intensive Care Unit. 2.2.2 Secondary 1. Determine treatment fidelity of participants randomized to the intervention arm. 2. Determine the prevalence of the therapeutic cuddling intervention in those randomized to the standard of care arm. 3. Determine the feasibility of measurement of key outcomes and co-variates (i.e., pain, agitation, sedation, delirium, analgosedation exposure, parental presence). 4. Describe the experience of patients, caregivers, and healthcare professionals in delivering/receiving the therapeutic cuddling intervention. 2.3 STUDY DESIGN Pilot feasibility randomized controlled trial of a structured co-designed therapeutic cuddling intervention as compared to the standard of care in a single tertiary care PICU. 2.4 DURATION 6 months to 1 year 2.5 LOCATION, DEPARTMENTS, AND FACILITY WHERE RESEARCH WILL BE UNDERTAKEN The pediatric intensive care unit at the Alberta Children's Hospital 2.6 SAMPLE SIZE A total sample size of 112 participants (56 per arm)

Recruiting
Has No Placebo

Alberta Children's Hospital

Image of University of Oklahoma Health Campus in Oklahoma City, United States.

Disulfiram for Rheumatoid Arthritis

18 - 75
All Sexes
Oklahoma City, OK

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent joint inflammation and systemic immune activation. Obesity is common among individuals with RA and is associated with increased disease activity, reduced treatment response, and worse functional outcomes. Inflammation in adipose tissue, driven in part by activation of the NLRP3 inflammasome and downstream gasdermin D (GSDMD)-mediated pathways, may contribute to systemic inflammation and RA disease severity. Disulfiram (DSF), an FDA-approved medication for alcohol use disorder, has recently been identified as an inhibitor of GSDMD-mediated inflammatory signaling and pyroptosis. Preclinical studies suggest that DSF reduces inflammasome activation, inflammatory cytokine release, and metabolic dysfunction. This study is a 12-week, randomized, double-blind, placebo-controlled pilot trial designed to evaluate the safety, tolerability, and preliminary efficacy of DSF in overweight and obese adults with active RA despite stable disease-modifying antirheumatic drug (DMARD) therapy. Participants will be randomized to receive either DSF (250 mg daily) or placebo. The primary objective is to assess safety and tolerability. Secondary and exploratory objectives include evaluating the effects of DSF on systemic inflammation, RA disease activity, metabolic parameters, and adipose tissue inflammasome activation. Findings from this study will inform the feasibility and design of larger clinical trials targeting GSDMD-mediated inflammation in RA.

Phase 2
Waitlist Available

University of Oklahoma Health Campus

Beatriz Y Hanaoka, MD, MSc

Image of Hopital general de Montreal in Montreal, Canada.

Nurse-led Telehealth for Rheumatoid Arthritis

18+
All Sexes
Montreal, Canada

Canada urgently needs new ways to provide rheumatology care that improve treatment and make it easier for people to get high-quality care. E-health technology is a new and promising way to do this, but it hasn't been studied much yet in rheumatology. The investigators will test a new way to help people with rheumatoid arthritis at four clinics in Quebec. This study will check if the new approach is easy to use, fits well into the clinics' daily routine, and if both patients and healthcare workers find it helpful and acceptable. This new approach involves nurses helping patients check their own health from home using an online platform. 104 adults who have rheumatoid arthritis and who have had a flare-up or a change in their medication in the last three months, will participate. Some will start using the online self-monitoring tool right away for 16 months, while others will continue with their usual care for 8 months before trying the tool. During the time they use the tool, they will fill out monthly online questionnaires to check their health. A rheumatology nurse will review their answers, suggest any needed care, provide personalized health information, and be available to answer questions through messages. This new way of care, where nurses help patients monitor their rheumatoid arthritis from home, helps make better use of limited specialist time. It's more convenient for patients, especially those who live far away, and helps meet their needs between regular doctor visits while keeping the quality of care high.

Waitlist Available
Has No Placebo

Hopital general de Montreal (+3 Sites)

Laetitia Michou, MD PhD

Have you considered Diclofenac Potassium clinical trials?

We made a collection of clinical trials featuring Diclofenac Potassium, we think they might fit your search criteria.
Go to Trials

Have you considered Diclofenac Potassium clinical trials?

We made a collection of clinical trials featuring Diclofenac Potassium, we think they might fit your search criteria.
Go to Trials
Image of Northwestern University in Chicago, United States.

Treatment for Sciatica

Any Age
All Sexes
Chicago, IL

Back pain is the leading cause of disability and military medical boards across the globe. Epidural steroid injections (ESI) are the most commonly performed pain procedure in the world. There is strong evidence that the placebo effect for all pain treatments, including ESI, is greater than the intrinsic effect. The placebo effect is highly dependent on a patient's 'expectations', and therefore how the procedure is framed. This study aims to compare ESI when the procedure is framed very positively- as is often done in clinical practice vs. more neutrally (which is less commonly done in clinical practice but consistent with evidence). The placebo effect is also stronger for procedures than medications. The evidence on the benefits of ESI is highly dependent on whether it is compiled by interventional doctors who perform the procedure or non-interventional researchers. In order to determine how 'framing' a treatment affects pain outcomes, the investigative team will conduct a 3-arm randomized trial comparing positive framing of ESI, neutral framing of ESI, and medications, in patients with lumbosacral radiculopathy.

Recruiting
New This Month

Northwestern University (+1 Sites)

Steven P Cohen, MD

Image of University of Miami in Miami, United States.

Steroid Injections for Radiating Back Pain

18+
All Sexes
Miami, FL

This study aims to evaluate the efficacy of interlaminar steroid injections at treating pain in lumbar radiculopathy at varying doses, to evaluate the efficacy of interlaminar steroid injections at improving quality of life and function in lumbar radiculopathy at varying doses, and to evaluate difference in efficacy between triamcinolone and dexamethasone interlaminar steroid injections at treating pain in lumbar radiculopathy at varying doses, with the overarching hypotheses that there is no difference in reported pain reduction, quality of life, or function among patients receiving low, moderate, or high doses, and no difference in reported pain reduction between triamcinolone and dexamethasone.

Phase 4
Waitlist Available

University of Miami

Seyed A mostoufi, MD

Have you considered Diclofenac Potassium clinical trials?

We made a collection of clinical trials featuring Diclofenac Potassium, we think they might fit your search criteria.
Go to Trials