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What is Acular Ls
KetorolacThe Generic name of this drug
Treatment SummaryKetorolac is a non-steroidal anti-inflammatory drug (NSAID) used to reduce pain. It comes in the form of tablets, injections, nasal spray, and eye drops. Ketorolac is commonly used to treat postoperative pain, rheumatoid arthritis, osteoarthritis, menstrual disorders, headaches, spinal and soft tissue pain, and ankylosing spondylitis. It works as well as morphine and meperidine but without the side effects of opioids.
Toradolis the brand name
Acular Ls Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Toradol
Ketorolac
1991
316
Approved as Treatment by the FDA
Ketorolac, also called Toradol, is approved by the FDA for 2 uses like caudal epidural block therapy and induction of Nerve Block .caudal epidural block therapy
Used to treat caudal epidural block therapy in combination with Bupivacaine
induction of Nerve Block
Used to treat induction of Nerve Block in combination with Bupivacaine
Effectiveness
How Acular Ls Affects PatientsKetorolac is a non-selective painkiller that works by blocking the enzymes responsible for producing substances that contribute to inflammation and pain. Blocking the COX-1 enzyme can lead to an increased risk of bleeding and stomach ulcers, while blocking the COX-2 enzyme is what causes the desired anti-inflammatory and pain relief effects. However, it is not recommended to take ketorolac long-term as this can lead to dangerous side effects such as stomach bleeding, ulcers, and perforations.
How Acular Ls works in the bodyKetorolac helps reduce pain and inflammation by blocking the pathways that create prostaglandins. It works by targeting two enzymes, COX-1 and COX-2, but mainly works on the COX-2 enzyme. This enzyme is responsible for converting arachidonic acid into prostaglandins, which cause inflammation and pain. By blocking this pathway, ketorolac stops the creation of these prostaglandins and reduces pain and inflammation. It is usually given as a racemic mixture, but the "S" enantiomer is mainly responsible for its effects.
When to interrupt dosage
The prescribed measure of Acular Ls is contingent upon the indicated condition, including Eye, Macular Edema, Cystoid and Pericarditis Acute. The magnitude of dosage is subject to the method of administration (e.g. Tablet - Oral or Ophthalmic) delineated in the following table.Condition
Dosage
Administration
corneal refractive surgery
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Eye
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
induction of Nerve Block
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
induction of Local Anaesthesia
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Eye Pain
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Pericarditis Acute
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Inflammation
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Induced Hyperthermia
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Macular Edema, Cystoid
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
caudal epidural block therapy
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Miosis disorder
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Macular Edema
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Cataract Surgery
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Intraocular Lens Replacement
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Acute Coryza
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Macular Edema, Cystoid
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Local Anaesthesia therapy
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Pupil
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
postoperative ocular pain
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Pain
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Warnings
Acular Ls ContraindicationsCondition
Risk Level
Notes
Heart failure
Do Not Combine
Hyperkalemia
Do Not Combine
Renal Insufficiency
Do Not Combine
Hemorrhagic Disorders
Do Not Combine
Kidney Failure
Do Not Combine
A History of Gastric or Duodenal Ulcers
Do Not Combine
Liver Diseases
Do Not Combine
Major Surgery
Do Not Combine
Pulse Frequency
Do Not Combine
Gastrointestinal Hemorrhage
Do Not Combine
Crohn's Disease
Do Not Combine
suspected cerebrovascular bleeding
Do Not Combine
active Gastrointestinal Bleeding
Do Not Combine
NSAID-Induced Asthma
Do Not Combine
Severe Hepatic Impairment
Do Not Combine
incomplete hemostasis
Do Not Combine
Coronary Artery Bypass Grafting
Do Not Combine
Gastrointestinal Perforation
Do Not Combine
Pulse Frequency
Do Not Combine
Hemorrhage
Do Not Combine
Peptic Ulcer
Do Not Combine
Pulse Frequency
Do Not Combine
Labour
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Third trimester of pregnancy
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Ketorolac may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Ketorolac may interact with Pulse Frequency
Common Acular Ls Drug Interactions
Drug Name
Risk Level
Description
Aceclofenac
Major
The risk or severity of adverse effects can be increased when Ketorolac is combined with Aceclofenac.
Acemetacin
Major
The risk or severity of adverse effects can be increased when Ketorolac is combined with Acemetacin.
Acetylsalicylic acid
Major
The risk or severity of adverse effects can be increased when Ketorolac is combined with Acetylsalicylic acid.
Alclofenac
Major
The risk or severity of adverse effects can be increased when Ketorolac is combined with Alclofenac.
Alminoprofen
Major
The risk or severity of adverse effects can be increased when Ketorolac is combined with Alminoprofen.
Acular Ls Toxicity & Overdose RiskTaking ketorolac may cause abdominal pain, indigestion, nausea, and headaches in more than 10% of patients. Other common symptoms of an overdose include vomiting, epigastric pain, gastrointestinal bleeding, fatigue and drowsiness, kidney damage or failure, high blood pressure, and coma. Women who are pregnant or nursing should exercise caution when taking ketorolac as it can be passed through breast milk and may cause premature closure of the fetal ductus arteriosus. Women who are trying to conceive should avoid taking ketorolac as it may affect fertility.
Acular Ls Novel Uses: Which Conditions Have a Clinical Trial Featuring Acular Ls?
188 active clinical trials are presently analyzing the potential of Acular LS to ameliorate Macular Edema, Cystoid, acute, moderate Pain and Intraocular Lens Replacement.Condition
Clinical Trials
Trial Phases
Inflammation
66 Actively Recruiting
Not Applicable, Early Phase 1, Phase 1, Phase 2, Phase 3, Phase 4
caudal epidural block therapy
5 Actively Recruiting
Not Applicable, Phase 4
Induced Hyperthermia
0 Actively Recruiting
Intraocular Lens Replacement
0 Actively Recruiting
Acute Coryza
0 Actively Recruiting
Macular Edema, Cystoid
0 Actively Recruiting
induction of Nerve Block
0 Actively Recruiting
Pupil
0 Actively Recruiting
Local Anaesthesia therapy
0 Actively Recruiting
corneal refractive surgery
0 Actively Recruiting
Seasonal Allergic Conjunctivitis
0 Actively Recruiting
Eye Pain
1 Actively Recruiting
Phase 1
postoperative ocular pain
0 Actively Recruiting
Eye
0 Actively Recruiting
Ocular Itching
0 Actively Recruiting
Pericarditis Acute
0 Actively Recruiting
Miosis disorder
0 Actively Recruiting
Macular Edema, Cystoid
0 Actively Recruiting
Macular Edema
0 Actively Recruiting
Cataract Surgery
2 Actively Recruiting
Not Applicable, Phase 4
Acular Ls Reviews: What are patients saying about Acular Ls?
5Patient Review
3/11/2008 This medication has a bit of a burning sensation upon application, but it subsides quickly.
5Patient Review
8/12/2008 This medicine is amazing! I had a scratch at the back of my eye that was causing me so much pain, but after taking this it just vanished. Best sleep ever!
3Patient Review
10/27/2008 About a week after my cataract surgery, I started using this treatment four times daily. The day after I stopped, I developed throbbing and redness in the affected eye, as well as tearing. I'm seeing my eye surgeon tomorrow, but in the meantime, does anyone know if this is normal?
1.7Patient Review
6/17/2009 I was very disappointed with this treatment. It did nothing to ease my pain, even temporarily, and it was quite expensive.
Patient Q&A Section about acular ls
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How long can you use ACULAR eye drops?
"The recommended length of use for ACULAR® eye drops is 2-4 weeks, as prescribed by a doctor."
Answered by AI
What is Acular LS used for?
"NSAIDs are a type of medication used to relieve pain, burning, and stinging. Ketorolac is a specific NSAID that is used to relieve symptoms following corneal refractive surgery."
Answered by AI
Are ACULAR eye drops an antibiotic?
"Acular is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve itching in the eyes that is caused by seasonal allergies. Acular is also used to reduce swelling, pain, and burning or stinging after cataract surgery or corneal refractive surgery."
Answered by AI
Is ACULAR eye drops a steroid?
"Acular (ketorolac eye drops) belongs to a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs), which is different from steroids. Even though they are different types of drugs, steroids and NSAIDs are often used for similar conditions, such as eye pain or inflammation."
Answered by AI
Clinical Trials for Acular Ls
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