Mediterranean Diet for Toddler Health

(MUNCHIES Trial)

DM
Overseen ByDr. Maryam Kebbe, PhD, CLC
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

Toddlerhood (ages 2-3) is a critical window when the gut microbiome is still developing and eating habits are being established. Yet, many Canadian toddlers eat diets high in sugar and salt, which may affect long-term health. This study will test whether a MED diet can improve dietary inflammation, gut health, and body composition in toddlers and whether a tailored nutrition education program for parents can help families maintain healthy eating patterns.

In this study, toddlers will be randomly assigned to a 3-week MED diet or their usual diet. Families in the MED diet group will receive free meal boxes for the 3 weeks, plus guidance from a nutrition researcher through a structured education program. The standard diet group will continue their regular diet with general nutrition advice. Researchers will collect dietary information, body composition assessments, and stool samples to measure gut microbiome composition and metabolites.

This first study of a controlled diet intervention in toddlers, combining behavioral support, high-quality food provision, and advanced gut microbiome analysis, will help understand how early diet shapes lifelong eating habits and health, guiding public health strategies and precision nutrition approaches to prevent chronic disease from early life.

Who Is on the Research Team?

DM

Dr. Maryam Kebbe, PhD, CLC

Principal Investigator

University of New Brunswick

Are You a Good Fit for This Trial?

The MUNCHIES study is for toddlers aged 2-3 whose parents are over 19, can communicate in English, and agree to follow a Mediterranean diet for their child. Eligible toddlers must have been born full-term with normal birth weight and can be delivered naturally or via C-section. Parents should commit to a nutrition program and provide necessary measurements and samples.

Inclusion Criteria

I am willing to provide my toddler's measurements and a stool sample.
I am a parent and I am 19 years old or older.
My child is between 2 and 3 years old.
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Toddlers are assigned to either a Mediterranean diet or their usual diet for 3 weeks. The MED diet group receives free meal boxes and nutrition education.

3 weeks
Weekly sessions (in-person or virtual)

Follow-up

Participants are monitored for dietary adherence, gut microbiome changes, and body composition at 3 weeks and 3 months post-baseline.

3 months
Assessments at 3 weeks and 3 months

Nutrition Education Program

Families participate in a tailored nutrition education program to promote adherence to the prescribed diets.

3 months
Nine weekly sessions

What Are the Treatments Tested in This Trial?

Interventions

  • Mediterranean Diet Nutrition Program
  • Standard Diet Education Program

Trial Overview

This trial tests if a Mediterranean Diet improves toddler health compared to usual diets. Toddlers will either receive the special diet with meal boxes and education for parents or continue regular eating habits with basic nutrition advice. The impact on gut health, inflammation, body composition, and long-term dietary patterns will be studied.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Mediterranean Diet InterventionExperimental Treatment1 Intervention
Group II: Standard DietActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of New Brunswick

Lead Sponsor

Trials
25
Recruited
2,700+