Eletriptan Hydrobromide

Migraine with Aura, Migraine without Aura
Treatment
3 Active Studies for Eletriptan Hydrobromide

What is Eletriptan Hydrobromide

EletriptanThe Generic name of this drug
Treatment SummaryEletriptan is a prescription medication used to stop migraine headaches. It was developed by Pfizer Inc and is part of a class of drugs called triptans.
Relpaxis the brand name
image of different drug pills on a surface
Eletriptan Hydrobromide Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Relpax
Eletriptan
2002
26

Effectiveness

How Eletriptan Hydrobromide Affects PatientsEletriptan works by activating certain receptors in the body. In animal studies, it was found to reduce blood flow in the carotid artery and reduce the size of the coronary artery, while also decreasing activity in the trigeminal nerve.
How Eletriptan Hydrobromide works in the bodyEletriptan binds to a few serotonin receptors in the brain which helps to reduce migraine pain. It works by constricting the blood vessels in the brain and inhibiting the release of pain-causing molecules. Eletriptan does not affect other receptors such as adrenergic, dopaminergic, muscarinic, or opioid receptors.

When to interrupt dosage

The prescribed measure of Eletriptan Hydrobromide is contingent upon the diagnosed condition. The amount of dosage alters, in accordance with the delivery technique (e.g. Tablet, film coated - Oral or Tablet, film coated) specified in the table beneath.
Condition
Dosage
Administration
Migraine without Aura
, 20.0 mg, 40.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral
Migraine with Aura
, 20.0 mg, 40.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral

Warnings

Eletriptan Hydrobromide Contraindications
Condition
Risk Level
Notes
intestinal ischemia
Do Not Combine
Migraine with Aura
Do Not Combine
Coronary Vasospasm
Do Not Combine
Pulse Frequency
Do Not Combine
Stroke
Do Not Combine
Pulse Frequency
Do Not Combine
arrhythmias associated with conduction disorders
Do Not Combine
Peripheral Vascular Disease
Do Not Combine
Pulse Frequency
Do Not Combine
Atrioventricular Block
Do Not Combine
Pulse Frequency
Do Not Combine
Transient Ischemic Attack
Do Not Combine
Pulse Frequency
Do Not Combine
Hypertensive disease
Do Not Combine
Coronary Artery Disease
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Hemiplegic migraine
Do Not Combine
There are 20 known major drug interactions with Eletriptan Hydrobromide.
Common Eletriptan Hydrobromide Drug Interactions
Drug Name
Risk Level
Description
Amitriptyline
Major
The metabolism of Amitriptyline can be decreased when combined with Eletriptan.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Eletriptan.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Eletriptan.
Azelastine
Major
Eletriptan may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Capmatinib
Major
The serum concentration of Capmatinib can be decreased when it is combined with Eletriptan.
Eletriptan Hydrobromide Toxicity & Overdose RiskTaking too much of a 5-HT1B/1D agonist could lead to high blood pressure or more serious heart problems.
image of a doctor in a lab doing drug, clinical research

Eletriptan Hydrobromide Novel Uses: Which Conditions Have a Clinical Trial Featuring Eletriptan Hydrobromide?

Currently, 4 active clinical trials are investigating the potential of Eletriptan Hydrobromide to alleviate Migraine Without Aura.
Condition
Clinical Trials
Trial Phases
Migraine with Aura
0 Actively Recruiting
Migraine without Aura
3 Actively Recruiting
Not Applicable

Eletriptan Hydrobromide Reviews: What are patients saying about Eletriptan Hydrobromide?

5Patient Review
7/27/2020
Eletriptan Hydrobromide for Migraine Headache
Relpax has been an absolute godsend. It's the only medication that has ever worked for my migraines, and it does so within 30 minutes. If you're considering trying a triptan, just be sure to take it as soon as you start feeling a migraine coming on.
5Patient Review
5/9/2008
Eletriptan Hydrobromide for Migraine Headache
5Patient Review
2/18/2009
Eletriptan Hydrobromide for Migraine Headache
if you take this medication as soon as you start feeling sick, it works really well and quickly. I didn't experience any negative side effects.
5Patient Review
2/24/2010
Eletriptan Hydrobromide for Migraine Headache
This is the most effective triptan I've tried, by far. It works within two hours, and I only need to take it once. Of course, it's very expensive.
5Patient Review
9/16/2008
Eletriptan Hydrobromide for Migraine Headache
If you take this drug as soon as you feel a migraine coming on, it's extremely effective. Just resting for 15-30 minutes is often all I need to make the headache go away entirely.
View All Reviews
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Patient Q&A Section about eletriptan hydrobromide

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the side effects of eletriptan?

"The following text is about the side effects of eletriptan. Eletriptan can commonly cause chest/jaw/neck tightness, pain, or pressure. These side effects are usually not serious. However, they can be like symptoms of a heart attack, which may include chest/jaw/left arm pain, shortness of breath, or unusual sweating."

Answered by AI

How strong is eletriptan?

"Eletriptan (Relpax) is available in two strengths which can be taken as a single dose: 20 mg and 40 mg. The recommended dose for eletriptan (Relpax) is 1 tablet consumed orally once for migraine pain. If the headache returns, the dose can be repeated 2 hours after the initial dose. Do not consume more than 80 mg in a day."

Answered by AI

What is eletriptan hydrobromide used for?

"Eletriptan is a drug used to treat acute migraine headaches in adults. It is not effective in preventing migraine headaches or cluster headaches. Eletriptan works by reducing the pain associated with migraine headaches by affecting the brain. It is classified as a triptan, a group of drugs used to treat migraines."

Answered by AI

How long does eletriptan take to work?

"Cluster headaches typically only last for 30 to 45 minutes, but in some cases they can last for a few hours. Relpax may take up to two hours to take full effect. However, by that time the cluster headache may already be gone. Relpax is not effective in preventing future cluster headaches."

Answered by AI

Clinical Trials for Eletriptan Hydrobromide

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