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Eletriptan Hydrobromide
Migraine with Aura, Migraine without Aura
Treatment
4 Active Studies for Eletriptan Hydrobromide
Treatment for
Migraine with Aura
What is Eletriptan Hydrobromide
EletriptanThe Generic name of this drug
Treatment SummaryEletriptan is a prescription medication used to stop migraine headaches. It was developed by Pfizer Inc and is part of a class of drugs called triptans.
Relpaxis the brand name
Eletriptan Hydrobromide Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Relpax
Eletriptan
2002
26
Effectiveness
How Eletriptan Hydrobromide Affects PatientsEletriptan works by activating certain receptors in the body. In animal studies, it was found to reduce blood flow in the carotid artery and reduce the size of the coronary artery, while also decreasing activity in the trigeminal nerve.
How Eletriptan Hydrobromide works in the bodyEletriptan binds to a few serotonin receptors in the brain which helps to reduce migraine pain. It works by constricting the blood vessels in the brain and inhibiting the release of pain-causing molecules. Eletriptan does not affect other receptors such as adrenergic, dopaminergic, muscarinic, or opioid receptors.
When to interrupt dosage
The prescribed measure of Eletriptan Hydrobromide is contingent upon the diagnosed condition. The amount of dosage alters, in accordance with the delivery technique (e.g. Tablet, film coated - Oral or Tablet, film coated) specified in the table beneath.Condition
Dosage
Administration
Migraine without Aura
, 20.0 mg, 40.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral
Migraine with Aura
, 20.0 mg, 40.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral
Warnings
Eletriptan Hydrobromide ContraindicationsCondition
Risk Level
Notes
intestinal ischemia
Do Not Combine
Migraine with Aura
Do Not Combine
Coronary Vasospasm
Do Not Combine
Pulse Frequency
Do Not Combine
Stroke
Do Not Combine
Pulse Frequency
Do Not Combine
arrhythmias associated with conduction disorders
Do Not Combine
Peripheral Vascular Disease
Do Not Combine
Pulse Frequency
Do Not Combine
Atrioventricular Block
Do Not Combine
Pulse Frequency
Do Not Combine
Transient Ischemic Attack
Do Not Combine
Pulse Frequency
Do Not Combine
Hypertensive disease
Do Not Combine
Coronary Artery Disease
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Hemiplegic migraine
Do Not Combine
Common Eletriptan Hydrobromide Drug Interactions
Drug Name
Risk Level
Description
Amitriptyline
Major
The metabolism of Amitriptyline can be decreased when combined with Eletriptan.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Eletriptan.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Eletriptan.
Azelastine
Major
Eletriptan may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Capmatinib
Major
The serum concentration of Capmatinib can be decreased when it is combined with Eletriptan.
Eletriptan Hydrobromide Toxicity & Overdose RiskTaking too much of a 5-HT1B/1D agonist could lead to high blood pressure or more serious heart problems.
Eletriptan Hydrobromide Novel Uses: Which Conditions Have a Clinical Trial Featuring Eletriptan Hydrobromide?
Currently, 4 active clinical trials are investigating the potential of Eletriptan Hydrobromide to alleviate Migraine Without Aura.Condition
Clinical Trials
Trial Phases
Migraine with Aura
0 Actively Recruiting
Migraine without Aura
4 Actively Recruiting
Not Applicable, Phase 4
Eletriptan Hydrobromide Reviews: What are patients saying about Eletriptan Hydrobromide?
5Patient Review
7/27/2020 Relpax has been an absolute godsend. It's the only medication that has ever worked for my migraines, and it does so within 30 minutes. If you're considering trying a triptan, just be sure to take it as soon as you start feeling a migraine coming on.
5Patient Review
5/9/20085Patient Review
2/18/2009 if you take this medication as soon as you start feeling sick, it works really well and quickly. I didn't experience any negative side effects.
5Patient Review
2/24/2010 This is the most effective triptan I've tried, by far. It works within two hours, and I only need to take it once. Of course, it's very expensive.
5Patient Review
9/16/2008 If you take this drug as soon as you feel a migraine coming on, it's extremely effective. Just resting for 15-30 minutes is often all I need to make the headache go away entirely.
5Patient Review
2/12/2010 This medication has been working well for me. I was experiencing dizziness and wasn't sure if it was the medication, but I think it might be a side effect. I've also felt very emotional at times while taking Relpax.
4.3Patient Review
12/8/2009 I get really bad lockjaw from this medicine, to the point where it interferes with my ability to work. However, it's much more effective than any other treatment I've tried.
4.3Patient Review
3/9/2009 Relpax has been great for me, significantly reducing the severity of my headaches. The only downside is how expensive they are.
4.3Patient Review
4/17/2014 This is the only medication that has ever stopped my migraine. It 'cures' the migrane within an hour and continues to work for close to 24 hours. It is important to take it as soon as the headache starts for best results. I do have trouble getting the pill out of the package. I keep a pair of scissors next to the package for that reason. The medication makes me sleepy, but in a good way because it relaxes me so much.
4Patient Review
12/4/2018 The medication works well. I get so frustrated trying to get the pill out of the package. I was taking Azor and that package is the same way - impossible to open without a knife for something similar to poke a hole in the back of the package. If they can't put it in a bottle then at least make it easier to poke the pill out!
3.7Patient Review
2/10/2010 This medication was effective, but I didn't like the side effects. I felt dizzy and lightheaded for not just the day of treatment, but also the next day. It made it hard to get up and do my daily activities.
3.3Patient Review
5/22/2014 I experienced some very unpleasant side effects from this medication, including lockjaw and dizziness.
2.3Patient Review
5/22/2021 I have not found this medication to be helpful at all for my migraines. Very disappointing and now I'm considering Botox injections as a next step.
Patient Q&A Section about eletriptan hydrobromide
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What are the side effects of eletriptan?
"The following text is about the side effects of eletriptan. Eletriptan can commonly cause chest/jaw/neck tightness, pain, or pressure. These side effects are usually not serious. However, they can be like symptoms of a heart attack, which may include chest/jaw/left arm pain, shortness of breath, or unusual sweating."
Answered by AI
How strong is eletriptan?
"Eletriptan (Relpax) is available in two strengths which can be taken as a single dose: 20 mg and 40 mg. The recommended dose for eletriptan (Relpax) is 1 tablet consumed orally once for migraine pain. If the headache returns, the dose can be repeated 2 hours after the initial dose. Do not consume more than 80 mg in a day."
Answered by AI
What is eletriptan hydrobromide used for?
"Eletriptan is a drug used to treat acute migraine headaches in adults. It is not effective in preventing migraine headaches or cluster headaches. Eletriptan works by reducing the pain associated with migraine headaches by affecting the brain. It is classified as a triptan, a group of drugs used to treat migraines."
Answered by AI
How long does eletriptan take to work?
"Cluster headaches typically only last for 30 to 45 minutes, but in some cases they can last for a few hours. Relpax may take up to two hours to take full effect. However, by that time the cluster headache may already be gone. Relpax is not effective in preventing future cluster headaches."
Answered by AI
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