Axert

Migraine
Treatment
1 FDA approval
20 Active Studies for Axert

What is Axert

AlmotriptanThe Generic name of this drug
Treatment SummaryAlmotriptan is a medication used to treat migraine headaches. It belongs to a group of drugs called serotonin receptor agonists and works by narrowing blood vessels in the brain, blocking pain signals from being sent to the brain, and preventing the release of certain natural substances that cause migraine symptoms like pain, nausea, and more. Almotriptan does not prevent migraine attacks.
Axertis the brand name
Axert Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Axert
Almotriptan
2001
13

Approved as Treatment by the FDA

Almotriptan, commonly known as Axert, is approved by the FDA for 1 uses which include Migraine .
Migraine
Helps manage Migraine

Effectiveness

How Axert Affects PatientsAlmotriptan is a drug used to treat migraine headaches in adults. It works by activating a specific type of serotonin receptor, which helps reduce the pain of a migraine attack. Almotriptan also causes blood vessels in the head to become narrower, which helps lessen the headache pain. Studies in animals have shown that this drug also works on nerves in the head, which may also play a role in its effectiveness.
How Axert works in the bodyAlmotriptan connects to two receptors in the brain, which causes the blood vessels to become narrower.

When to interrupt dosage

The prescribed dosage of Axert is contingent upon the recognized condition. The measure of dosage shifts, depending on the technique of delivery featured in the table below.
Condition
Dosage
Administration
Migraine
, 12.5 mg, 6.25 mg
, Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral

Warnings

There are 20 known major drug interactions with Axert.
Common Axert Drug Interactions
Drug Name
Risk Level
Description
Amitriptyline
Major
The metabolism of Amitriptyline can be decreased when combined with Almotriptan.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Almotriptan.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Almotriptan.
Azelastine
Major
Almotriptan may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Almotriptan.

Axert Novel Uses: Which Conditions Have a Clinical Trial Featuring Axert?

58 active trials are currently being conducted to investigate the efficacy of Axert in treating Migraine Headaches.
Condition
Clinical Trials
Trial Phases
Migraine
53 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1

Axert Reviews: What are patients saying about Axert?

5Patient Review
12/15/2010
Axert for Migraine Headache
Among the five different triptans I've tried, this is the only one that gave me relief without any nasty side effects. One dose was all it usually took, too!
5Patient Review
2/7/2014
Axert for Migraine Headache
I find that Axert works really well for me in terms of stopping migraines. I only have to take one pill and it usually does the trick. However, I'm a bit frustrated that my insurance only covers 24 pills for 3 months.
5Patient Review
6/14/2016
Axert for Migraine Headache
Axert is much better than Imitrex in my opinion. It doesn't give me heart palpitations or anxiety like the other drug did. Plus, it's actually really effective at stopping headaches. Yes, it's expensive-- but for me, it's worth it since I only need to take it a few times a year.
5Patient Review
4/24/2011
Axert for Migraine Headache
This treatment is amazing. Within 30 minutes, I'm usually pain-free with no side effects. In the past, I've been forced by insurance companies to try generic drugs, but none of them have worked as well as this one. Now I'm being forced again to switch to a generic, but I really need something that works quickly and effectively, and that's what Axert does for me.
5Patient Review
1/11/2012
Axert for Migraine Headache
Axert has been the only medication that consistently eliminates my migraines. I've tried over 20 different medications and nothing has worked as well as this one.
5Patient Review
3/19/2012
Axert for Migraine Headache
I used to suffer from chronic migraines before I started taking this medication. Now, my migraines are much more manageable and I can actually function during the day. This medication has definitely made a positive impact on my life.
5Patient Review
10/23/2012
Axert for Migraine Headache
This medication is highly effective in relieving migraines, including visual disturbances, sound & light sensitivity, headache, & nausea.
5Patient Review
8/1/2013
Axert for Migraine Headache
I've been getting migraines since I was 23, and let me tell you: this drug is a life saver. When other medications have failed, Axert has always been there for me.
5Patient Review
11/5/2015
Axert for Migraine Headache
Axert is the best migraine medication I've tried. Other medications would give me extremely uncomfortable side effects, but Axert has very little to no side effects. Plus, it always takes my migraines away completely!
5Patient Review
2/4/2010
Axert for Migraine Headache
5Patient Review
2/24/2010
Axert for Migraine Headache
4.7Patient Review
7/30/2014
Axert for Migraine Headache
It's expensive but it does the job well.
2.3Patient Review
1/26/2010
Axert for Migraine Headache
1Patient Review
7/11/2016
Axert for Migraine Headache
While this medication did help to lessen the pain of my migraines, it made me so incredibly ill that it was not worth continuing to take.

Patient Q&A Section about axert

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How long does it take for Axert to work?

"The medication Axert is designed to reduce the symptoms of migraines that have already begun. It typically starts working within 30 minutes to 2 hours. Axert should not be used as a way to prevent migraines from occurring, as overusing this medication can cause headaches from medication overuse."

Answered by AI

What is Axert used for?

"Almotriptan is a drug that is used to treat migraines. It helps to relieve the pain and other symptoms associated with migraines, such as nausea, vomiting, and sensitivity to light and sound. When this drug is used promptly, it can help you to return to your normal routine and may decrease your need for other pain medications."

Answered by AI

Is Axert still available?

"The Axert brand name has been discontinued and replaced by generic equivalents."

Answered by AI

Is Axert a triptan?

"Axert is a medication used to treat migraine headaches in adults and adolescents who are at least 12 years old. It works by affecting a certain natural chemical (serotonin) that constricts blood vessels in the brain. Axert will only treat a headache that has already begun."

Answered by AI

Clinical Trials for Axert

Have you considered Axert clinical trials? We made a collection of clinical trials featuring Axert, we think they might fit your search criteria.
Have you considered Axert clinical trials? We made a collection of clinical trials featuring Axert, we think they might fit your search criteria.
Have you considered Axert clinical trials? We made a collection of clinical trials featuring Axert, we think they might fit your search criteria.