Zylet

Bacteria, Cystic Fibrosis, Septicemia + 19 more

Treatment

1 Active Study for Zylet

Treatment for

Bacteria

What is Zylet

Tobramycin

The Generic name of this drug

Treatment Summary

Aminoglycosides, many of which are derived directly from _Streptomyces_ spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms.[A232294] Inhaled tobramycin is notable for its use in treating chronic _Pseudomonas aeruginosa_ infections in cystic fibrosis patients, as _P. aeruginosa_ is notoriously inherently resistant to many antibiotics.[A232294, A232299, L32739] However, tobramycin can also be administered intravenously and topically to treat a variety of infections caused by susceptible bacteria.[L32744, L32749] Its use is limited in some cases by characteristic toxicities such as nephrotoxicity and ototoxicity, yet it remains a valuable option in the face of growing resistance to front-line antibiotics such as β-lactams and cephalosporins.[A232294, A232349, L32739, L32749] Tobramycin was approved by the FDA in 1975 and is currently available in a variety of forms for administration by inhalation, injection, and external application to the eye (ophthalmic).[L32739, L32744, L32749]

Tobrex

is the brand name

image of different drug pills on a surface

Zylet Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Tobrex

Tobramycin

1981

166

When to interrupt dosage

The recommended measure of Zylet is contingent upon the diagnosed issue, for instance Ocular Inflammation, Conjunctivitis infective and Herpes Zoster Keratitis. Dosage additionally relies upon the strategy of administration (e.g. Gel - Ophthalmic or Suspension / drops) as detailed in the table beneath.

Condition

Dosage

Administration

concomitant use of NSAID

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

Inflammation

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

Cystic Fibrosis

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

Bacterial Infections

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

Burkholderia Cepacia Infection

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

Bacterial Peritonitis

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

FEV1 <25% predicted

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

Septicemia

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

Conjunctivitis

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

Urinary tract infection

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

Eye Infections, Bacterial

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

Otitis

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

External auditory canal structure

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

FEV1 >80% predicted

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

Eye Infections

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

Cystic Fibrosis

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

Bacteria

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

ocular bacterial infections

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

Adrenal Cortex Hormones

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

Intraabdominal Infections

, 0.003 mg/mg, 40.0 mg/mL, 300.0 mg/mL, 0.8 mg/mL, 10.0 mg/mL, 3.0 mg/mL, 120.0 mg/mL, 0.3 %, 1200.0 mg, 28.0 mg, 80.0 mg, 60.0 mg, 1.2 mg/mL, 60.0 mg/mL, 170.0 mg

, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Solution, Oral, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution - Ophthalmic, Suspension / drops - Ophthalmic, Suspension / drops, Solution - Respiratory (inhalation), Respiratory (inhalation), Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intravenous, Capsule, Capsule - Respiratory (inhalation), Liquid - Intramuscular; Intravenous, Liquid, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Suspension, Suspension - Ophthalmic, Capsule - Oral; Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid - Intravenous, Solution - Oral; Respiratory (inhalation), Liquid - Ophthalmic, Oral; Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation)

Warnings

Zylet has eight contraindications, and thus should not be ingested when dealing with any of the conditions identified in the following table.

Zylet Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

There are 20 known major drug interactions with Zylet.

Common Zylet Drug Interactions

Drug Name

Risk Level

Description

Neomycin

Major

The risk or severity of nephrotoxicity can be increased when Tobramycin is combined with Neomycin.

Tenofovir

Major

Tobramycin may increase the nephrotoxic activities of Tenofovir.

Tenofovir alafenamide

Major

Tobramycin may increase the nephrotoxic activities of Tenofovir alafenamide.

Tenofovir disoproxil

Major

Tobramycin may increase the nephrotoxic activities of Tenofovir disoproxil.

Vibrio cholerae CVD 103-HgR strain live antigen

Major

The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Tobramycin.

image of a doctor in a lab doing drug, clinical research

Zylet Novel Uses: Which Conditions Have a Clinical Trial Featuring Zylet?

Currently, 198 active trials are investigating the potential of Zylet to alleviate Seasonal Allergic Conjunctivitis, Iritis and Ocular Inflammation.

Condition

Clinical Trials

Trial Phases

Bacterial Infections

0 Actively Recruiting

Meningitis, Bacterial

0 Actively Recruiting

Bacteria

0 Actively Recruiting

Inflammation

0 Actively Recruiting

Eye Infections

0 Actively Recruiting

concomitant use of NSAID

0 Actively Recruiting

Cystic Fibrosis

0 Actively Recruiting

Osteomyelitis

0 Actively Recruiting

Burkholderia Cepacia Infection

0 Actively Recruiting

Adrenal Cortex Hormones

0 Actively Recruiting

Bacterial Peritonitis

0 Actively Recruiting

FEV1 <25% predicted

0 Actively Recruiting

ocular bacterial infections

0 Actively Recruiting

Urinary tract infection

0 Actively Recruiting

Eye Infections, Bacterial

0 Actively Recruiting

Cystic Fibrosis

0 Actively Recruiting

Intraabdominal Infections

1 Actively Recruiting

Not Applicable

Septicemia

0 Actively Recruiting

External auditory canal structure

0 Actively Recruiting

Otitis

0 Actively Recruiting

Zylet Reviews: What are patients saying about Zylet?

5

Patient Review

5/3/2016

Zylet for Allergic Conjunctivitis

I had no idea there were different types of pink eye, but I'm glad I found this medication. After just one dosage, the puffiness and redness around my eyes went away.

5

Patient Review

12/13/2010

Zylet for Allergic Conjunctivitis

I started seeing results after the first day of use. By the third day, my eyes were noticeably improved. This medication is working well for me and I am much better off because of it.

5

Patient Review

7/8/2014

Zylet for Inflammation of the Eye

Zylet was extremely effective in treating my infection and reducing the pain. I followed the instructions to a tee and saw results very quickly.

5

Patient Review

10/12/2011

Zylet for Allergic Conjunctivitis

Zylet is extremely effective for me. Within minutes of using it, my eyes stopped itching and the redness disappeared. My allergies have improved a lot since I started using this product.

4.3

Patient Review

6/3/2011

Zylet for Inflammation of the Eye

I started using this for allergic scleritis after lotemax failed to produce results. I noticed an immediate improvement upon use. I have had some excessive tearing, but as I already have dry-eye syndrome, it's not a huge deal to me.

3

Patient Review

9/29/2010

Zylet for Scratch Wound on Cornea

This treatment was effective for a time, but eventually the problem came back.

2

Patient Review

12/23/2013

Zylet for Inflammation of the Eye

I've been using the drops for five days now and, unfortunately, have only experienced more severe itching in my upper eyelid and face. I took Benedryl but it didn't help at all. I'm going to be contacting my doctor today.

2

Patient Review

2/28/2012

Zylet for Allergic Conjunctivitis

These drops were very expensive and unfortunately, they actually increased the pain I was experiencing. I had to discontinue use after only a day because the pain was unbearable. If you have dry eye, I would recommend avoiding this medication as it will likely make your symptoms worse.

2

Patient Review

6/22/2010

Zylet for Inflammation of the Eye

I used this drug for 2/1/2 months without seeing any improvement.

1.7

Patient Review

7/27/2010

Zylet for Inflammation of the Eye

My 87 year old mother took this medication and had a really adverse reaction. Her face got red, swollen, and developed sores. She only used the medication for a day or two before discontinuing use, but even still 3 days later she's experiencing these side effects.

1

Patient Review

12/19/2010

Zylet for Inflammation of the Eye

After using this medication for my elderly mother (as directed, one drop in each eye twice daily), she has been complaining of pain almost constantly. I notified the prescribing doctor and was told to use a different product alongside it; however, this has not alleviated the issue at all and may even be making it worse. I cannot continue putting her through this much discomfort and will stop the medication tomorrow morning.

1

Patient Review

11/3/2011

Zylet for Allergic Conjunctivitis

After applying the drops to my eye, I experienced horrible pain and stinging. This made my condition worse instead of better. Save yourself the money and get a sample from your doctor before buying this non-generic medication.

1

Patient Review

5/30/2015

Zylet for Allergic Conjunctivitis

After just three weeks of using this medication as prescribed, I developed vertigo and double vision. This led to a hospital stay for testing, which showed no cause for my symptoms. However, I'm confident that the Zylet is to blame. It's been seven months since I stopped taking it, and though the vertigo has subsided somewhat, the double vision persists and prevents me from driving.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about zylet

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Zylet a steroid?

"Zylet is a brand medication that is a combination of a steroid and antibiotic. It is effective in treating eye inflammation and bacterial eye infections. However, it can cause high eye pressure and eye injury if used for a long period of time."

Answered by AI

What is Zylet used to treat?

"This medication is used to treat conditions involving swelling (inflammation) of the eyes and to treat or prevent bacterial eye infections. This product contains tobramycin, an antibiotic. Tobramycin works by stopping the growth of bacteria."

Answered by AI

How long does it take for Zylet to work?

"You may be at an increased risk of developing an eye infection or its severity may worsen if you take corticosteroids. If you don't see an improvement in your symptoms after two days of using ZYLET®, you should consult your doctor."

Answered by AI

What are the side effects of Zylet eye drops?

"Some common side effects of taking Zylet include a burning or stinging feeling in the eyes, itchiness, redness, or discomfort. Other potential side effects include headaches, light sensitivity, and blurred vision."

Answered by AI

Clinical Trials for Zylet