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What is Alrex
LoteprednolThe Generic name of this drug
Alrexis the brand name
Alrex Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Alrex
Loteprednol
1998
16
Approved as Treatment by the FDA
Loteprednol, otherwise called Alrex, is approved by the FDA for 10 uses like Ocular Inflammation and Herpes Zoster Keratitis .Ocular Inflammation
Herpes Zoster Keratitis
Helps manage Herpes Zoster Keratitis
Eye
Iritis
Inflammation
Used to treat Inflammation in combination with Tobramycin
Conjunctivitis infective
Cyclitis
Seasonal Allergic Conjunctivitis
Superficial punctate keratitis
Helps manage Superficial punctate keratitis
ocular bacterial infections
Used to treat ocular bacterial infections in combination with Tobramycin
When to interrupt dosage
The amount of Alrex is contingent upon the determined condition, including Ocular Inflammation, Conjunctivitis infective and Herpes Zoster Keratitis. The measure of dosage fluctuates as per the delivery technique (e.g. Gel - Ophthalmic or Suspension / drops) featured in the table underneath.Condition
Dosage
Administration
Chickenpox
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Iritis
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Inflammation
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Eye infection viral
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Rosacea
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Superficial punctate keratitis
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Conjunctivitis infective
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Eye
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Seasonal Allergic Conjunctivitis
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Ocular Inflammation
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Herpes Zoster Keratitis
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Cyclitis
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
ocular bacterial infections
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Warnings
Alrex has eight contraindications, so it should not be employed when confronting any of the circumstances detailed in the following table.Alrex ContraindicationsCondition
Risk Level
Notes
Keratitis, Dendritic
Do Not Combine
conjunctiva
Do Not Combine
epithelial herpes simplex
Do Not Combine
Varicella
Do Not Combine
Vaccinia
Do Not Combine
epithelial herpes simplex keratitis
Do Not Combine
Eye Infections, Fungal
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Loteprednol may interact with Pulse Frequency
Common Alrex Drug Interactions
Drug Name
Risk Level
Description
2,4-thiazolidinedione
Moderate
The risk or severity of hyperglycemia can be increased when Loteprednol is combined with 2,4-thiazolidinedione.
AICA ribonucleotide
Moderate
The risk or severity of hyperglycemia can be increased when Loteprednol is combined with AICA ribonucleotide.
AMG-222
Moderate
The risk or severity of hyperglycemia can be increased when Loteprednol is combined with AMG-222.
Acarbose
Moderate
The risk or severity of hyperglycemia can be increased when Loteprednol is combined with Acarbose.
Acetohexamide
Moderate
The risk or severity of hyperglycemia can be increased when Loteprednol is combined with Acetohexamide.
Alrex Novel Uses: Which Conditions Have a Clinical Trial Featuring Alrex?
198 active studies are currently being conducted to evaluate the potential of Alrex in alleviating Seasonal Allergic Conjunctivitis, Iritis and Ocular Inflammation.Condition
Clinical Trials
Trial Phases
Inflammation
171 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 3, Phase 4
Conjunctivitis infective
0 Actively Recruiting
Superficial punctate keratitis
0 Actively Recruiting
Eye
0 Actively Recruiting
Iritis
0 Actively Recruiting
ocular bacterial infections
0 Actively Recruiting
Seasonal Allergic Conjunctivitis
0 Actively Recruiting
Eye infection viral
0 Actively Recruiting
Cyclitis
0 Actively Recruiting
Herpes Zoster Keratitis
0 Actively Recruiting
Chickenpox
3 Actively Recruiting
Phase 2, Phase 1
Rosacea
8 Actively Recruiting
Not Applicable, Early Phase 1, Phase 2, Phase 4
Ocular Inflammation
3 Actively Recruiting
Phase 2, Phase 4, Phase 3
Alrex Reviews: What are patients saying about Alrex?
5Patient Review
4/12/2009 Allergies are such a pain, but this medication really does the trick. It's the only thing that's worked for me in the past. However, I understand why my doctor is hesitant to prescribe it because of the potential risks involved.
5Patient Review
11/10/2011 Alrex provided quick and long-lasting relief from the incessant itchiness in my eyes.
5Patient Review
9/7/2012 Alrex is very effective for chronic inflammation, which I experience due to several conditions. The only downside is the cost of the medication.
5Patient Review
3/13/2009 I had some redness in my eye this morning, but after using Alrex just once today, it's already clearing up. I'm confident that it'll be gone completely soon.
5Patient Review
11/22/2009 This medication has been a great help for my chronic inflammation of the eye and eyelids. It's helped to reduce the swelling and redness, and has made my eyes much more clear and white. I use it 3 times a day for 3 weeks, and it's really helped with the pain with no side effects.
5Patient Review
6/13/2009 After three years of struggling with the zoster infection, this treatment finally gave me relief.
4Patient Review
1/27/2009 My doctor recommended this treatment to me for slight redness in the corners of my eyes. It worked great at first, but now the effects have worn off slightly. Sometimes my eyes throb after using it.
3.7Patient Review
1/17/2008 I've been using this medication for "dry eye" for two years now. I originally started because over-the-counter treatments weren't helping me, but I haven't seen much relief from this drug either. Furthermore, I recently read that these types of medications can cause glaucoma. So, all things considered, I've decided to stop taking it.
2.7Patient Review
3/15/2010 I've been using this for three days now and, unfortunately, have seen no improvement. My eyes are still red and itchy, and the watering hasn't stopped.
2.7Patient Review
11/3/20072.3Patient Review
4/7/2012 I saw no improvement after using as directed by my physician. In fact, my symptoms got worse.
2.3Patient Review
10/22/2022 The pressure I felt when using this medication was intense and unbearable. It gave me a migraine and made me nauseous. The next day I felt dizzy and foggy. Overall, it was a terrible experience that did the opposite of what I intended to use it for.
1.3Patient Review
12/29/2012 This medication did not clear up the issue of my red eyelids and eyes. Not only that, but they were also sore to the touch.
Patient Q&A Section about alrex
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Can you get Alrex over the counter?
"There is no version of Alrex available in the United States that is the same as what is being sold online. Note: Some online pharmacies may be selling a generic version of Alrex illegally."
Answered by AI
How long can I use Alrex?
"Length of treatment: This medication is only meant to be used for a short period of time, no more than 14 days. If you use this medication for 10 days or more, your doctor will need to check the pressure in your eye regularly to make sure it doesn't cause any damage such as cataracts or glaucoma."
Answered by AI
What are Alrex eye drops used for?
"This drug is designed to temporarily relieve seasonal allergy symptoms in the eyes, such as swelling, redness, and itching. Loteprednol is a type of drug known as a corticosteroid."
Answered by AI