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What is Blephamide
SulfacetamideThe Generic name of this drug
Treatment SummaryPrednisolone acetate is a type of steroid medication that was approved by the FDA in 1955. It works by blocking certain chemical processes in the body to reduce inflammation and swelling.
Blephamideis the brand name
Blephamide Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Blephamide
Sulfacetamide
1961
61
Effectiveness
How Blephamide Affects PatientsPrednisolone acetate is a type of corticosteroid that works by blocking signals in the body that cause inflammation, and promoting signals that reduce inflammation. Its effects last for a few hours, and patients often take doses much higher than the body naturally produces. Taking corticosteroids can suppress the body's ability to respond to stress and make it more likely to get infections, so patients should be aware of these risks.
How Blephamide works in the bodyCorticosteroids can help reduce inflammation by decreasing blood vessel widening and the flow of white blood cells to sites of inflammation. They also change gene expression in the body, reducing the production of substances linked to inflammation and increasing substances that reduce inflammation. Low doses reduce inflammation, while higher doses can suppress your immune system. In high doses over an extended period, corticosteroids also cause sodium levels to rise and potassium levels to drop.
When to interrupt dosage
The prescribed dosage of Blephamide is contingent upon the determined condition, for example Ocular Infections, Irritations and Inflammations, Ocular Inflammation and Inflammatory Conditions. The quantity of dosage changes, in light of the technique of delivery (e.g. Ophthalmic or Solution/drops - Ophthalmic) featured in the table beneath.Condition
Dosage
Administration
superficial ocular infections
0.1 mg/mg, , 100.0 mg/mL, 0.098 mg/mg, 300.0 mg/mL, 80.0 mg/mL, 0.009 mg/mg, 0.9 mg/mL, 0.09 mg/mg, 1000.0 mg/mL, 10.0 mg/mL, 90.0 mg/mL, 10.0 %, 100.0 mg, 0.01 mg/mg, 0.095 mg/mg, 150.0 mg/mL, 98.0 mg/mL, 0.0286 mg/mg, 0.28 mg/mg, 0.08 mg/mg, 0.05 mg/mg, 0.15 mg/mg, 0.0098 mg/mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Topical, Suspension - Topical, Solution, Solution - Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Aerosol, foam, Aerosol, foam - Topical, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid, Liquid - Topical, Swab, Swab - Topical, Cloth, Cloth - Topical, Rinse, Rinse - Topical, Gel, Gel - Topical, Kit, Suspension / drops, Suspension / drops - Ophthalmic, Soap, Soap - Topical, Liquid - Ophthalmic, Suspension - Ophthalmic, Shampoo, Shampoo - Topical, Emulsion, Emulsion - Topical, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Kit - Topical, Vaginal, Cream - Vaginal, Lotion / shampoo, Lotion / shampoo - Topical
Trachoma
0.1 mg/mg, , 100.0 mg/mL, 0.098 mg/mg, 300.0 mg/mL, 80.0 mg/mL, 0.009 mg/mg, 0.9 mg/mL, 0.09 mg/mg, 1000.0 mg/mL, 10.0 mg/mL, 90.0 mg/mL, 10.0 %, 100.0 mg, 0.01 mg/mg, 0.095 mg/mg, 150.0 mg/mL, 98.0 mg/mL, 0.0286 mg/mg, 0.28 mg/mg, 0.08 mg/mg, 0.05 mg/mg, 0.15 mg/mg, 0.0098 mg/mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Topical, Suspension - Topical, Solution, Solution - Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Aerosol, foam, Aerosol, foam - Topical, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid, Liquid - Topical, Swab, Swab - Topical, Cloth, Cloth - Topical, Rinse, Rinse - Topical, Gel, Gel - Topical, Kit, Suspension / drops, Suspension / drops - Ophthalmic, Soap, Soap - Topical, Liquid - Ophthalmic, Suspension - Ophthalmic, Shampoo, Shampoo - Topical, Emulsion, Emulsion - Topical, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Kit - Topical, Vaginal, Cream - Vaginal, Lotion / shampoo, Lotion / shampoo - Topical
Pink Eye
0.1 mg/mg, , 100.0 mg/mL, 0.098 mg/mg, 300.0 mg/mL, 80.0 mg/mL, 0.009 mg/mg, 0.9 mg/mL, 0.09 mg/mg, 1000.0 mg/mL, 10.0 mg/mL, 90.0 mg/mL, 10.0 %, 100.0 mg, 0.01 mg/mg, 0.095 mg/mg, 150.0 mg/mL, 98.0 mg/mL, 0.0286 mg/mg, 0.28 mg/mg, 0.08 mg/mg, 0.05 mg/mg, 0.15 mg/mg, 0.0098 mg/mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Topical, Suspension - Topical, Solution, Solution - Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Aerosol, foam, Aerosol, foam - Topical, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid, Liquid - Topical, Swab, Swab - Topical, Cloth, Cloth - Topical, Rinse, Rinse - Topical, Gel, Gel - Topical, Kit, Suspension / drops, Suspension / drops - Ophthalmic, Soap, Soap - Topical, Liquid - Ophthalmic, Suspension - Ophthalmic, Shampoo, Shampoo - Topical, Emulsion, Emulsion - Topical, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Kit - Topical, Vaginal, Cream - Vaginal, Lotion / shampoo, Lotion / shampoo - Topical
Acne Vulgaris
0.1 mg/mg, , 100.0 mg/mL, 0.098 mg/mg, 300.0 mg/mL, 80.0 mg/mL, 0.009 mg/mg, 0.9 mg/mL, 0.09 mg/mg, 1000.0 mg/mL, 10.0 mg/mL, 90.0 mg/mL, 10.0 %, 100.0 mg, 0.01 mg/mg, 0.095 mg/mg, 150.0 mg/mL, 98.0 mg/mL, 0.0286 mg/mg, 0.28 mg/mg, 0.08 mg/mg, 0.05 mg/mg, 0.15 mg/mg, 0.0098 mg/mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Topical, Suspension - Topical, Solution, Solution - Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Aerosol, foam, Aerosol, foam - Topical, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid, Liquid - Topical, Swab, Swab - Topical, Cloth, Cloth - Topical, Rinse, Rinse - Topical, Gel, Gel - Topical, Kit, Suspension / drops, Suspension / drops - Ophthalmic, Soap, Soap - Topical, Liquid - Ophthalmic, Suspension - Ophthalmic, Shampoo, Shampoo - Topical, Emulsion, Emulsion - Topical, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Kit - Topical, Vaginal, Cream - Vaginal, Lotion / shampoo, Lotion / shampoo - Topical
Warnings
Blephamide ContraindicationsCondition
Risk Level
Notes
Chronic Kidney Disease (CKD)
Do Not Combine
Common Blephamide Drug Interactions
Drug Name
Risk Level
Description
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Sulfacetamide.
Benzylpenicillin
Moderate
Sulfacetamide may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level.
Estetrol
Moderate
The therapeutic efficacy of Estetrol can be decreased when used in combination with Sulfacetamide.
Insulin argine
Moderate
The risk or severity of hypoglycemia can be increased when Sulfacetamide is combined with Insulin argine.
Insulin aspart
Moderate
The risk or severity of hypoglycemia can be increased when Sulfacetamide is combined with Insulin aspart.
Blephamide Toxicity & Overdose RiskThe lowest toxic dose of prednisolone acetate in mice is 1680 mg/kg. Those who overdose onprednisolone acetate may experience more severe side effects of corticosteroids. If the overdose was recent, it can be treated with gastric lavage or inducing vomiting. Chronic overdosing can be managed by reducing the dose or administering the drug every other day. An overdose through eye drops is not expected to cause any problems.
Blephamide Novel Uses: Which Conditions Have a Clinical Trial Featuring Blephamide?
189 active clinical trials are assessing the effectiveness of Blephamide in treating Inflammation, Inflammatory Conditions and Superficial Ocular Infections.Condition
Clinical Trials
Trial Phases
Trachoma
1 Actively Recruiting
Phase 4
superficial ocular infections
0 Actively Recruiting
Pink Eye
5 Actively Recruiting
Phase 4, Phase 3, Not Applicable, Phase 2
Acne Vulgaris
22 Actively Recruiting
Phase 4, Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 3
Blephamide Reviews: What are patients saying about Blephamide?
5Patient Review
6/21/2014 I get awful allergies in the spring, and this is the only medication that has given me any relief.
4Patient Review
10/9/2009 Worked great for about a day, but then the redness came right back. It looks like I have acne on my eyelid now.
2.3Patient Review
9/17/2009Patient Q&A Section about blephamide
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How do you use Blephamide ointment?
"When applying the medication, tilt your head back and look up. Squeeze the tube gently to place a 1/2 inch (1.3 centimeter) strip of ointment into the pouch created by pulling down your lower eyelid. Close your eyes gently for 1-2 minutes, rolling your eyeball in all directions to spread the medication."
Answered by AI
What is Blephamide used to treat?
"It will not work for other types of eye infections.
This medication is used to both prevent and treat eye infections, as well as to treat swelling in the eye. It contains sulfacetamide, an antibiotic that stops the growth of bacteria, and prednisolone, a corticosteroid that reduces inflammation. However, this medication will only work on bacterial eye infections, and not other types of eye infections."
Answered by AI
Is Blephamide a steroid?
"BLEPHAMIDE® ophthalmic suspension is a steroid/anti-infective combination drug that is indicated for treating steroid-responsive inflammatory ocular conditions when a corticosteroid is needed and when there is a risk of superficial bacterial ocular infection."
Answered by AI
What is the generic for Blephamide?
"There is no FDA-approved generic version of Blephamide available in the United States. Some online pharmacies may sell a counterfeit or unapproved version of the drug, which could be dangerous."
Answered by AI