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Laser Treatment for Acne
N/A
Waitlist Available
Led By Dieter Manstein, MD, PhD
Research Sponsored by Massachusetts General Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Ages 18 through 40
Any gender and any Fitzpatrick skin type
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change in pga score between baseline visit and post procedural visit
Awards & highlights
Study Summary
This trial is testing a laser to see if it can help people with moderate to severe acne.
Who is the study for?
This trial is for individuals aged 18-40 with moderate to severe nodular acne (PGA 3 or 4) who haven't responded to standard treatments. Participants must be in good health, willing to avoid sun exposure on treated areas, and not pregnant or breastfeeding. They shouldn't have had laser treatment or isotretinoin therapy recently.Check my eligibility
What is being tested?
The study tests a commercial laser's effectiveness in treating moderate to severe acne vulgaris. It aims to see if the laser can improve skin condition in those who've declined conventional therapies like oral isotretinoin.See study design
What are the potential side effects?
Potential side effects may include discomfort during treatment, redness, swelling, and temporary changes in skin pigmentation. There's also a risk of scarring and poor wound healing for some individuals.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am between 18 and 40 years old.
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My gender and skin type do not limit my participation.
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I cannot use or have chosen not to use standard treatments like oral isotretinoin.
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I am between 18 and 40 years old.
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I cannot take or have chosen not to take standard treatments like oral isotretinoin.
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I am willing to protect my skin from the sun during and for a year after the study.
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I have moderate to severe acne on my face.
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I am willing to protect my skin from the sun during and for a year after the study.
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My gender and skin type do not limit my participation.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ change in pga score between baseline visit and post procedural visit
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change in pga score between baseline visit and post procedural visit
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Changes in Physician's Global Assessment (PGA) of Acne Severity
Trial Design
1Treatment groups
Experimental Treatment
Group I: TreatmentExperimental Treatment1 Intervention
Subjects in this arm will undergo laser treatment on their active acne vulgaris lesions. Subjects will serve as their own control.
Find a Location
Who is running the clinical trial?
Massachusetts General HospitalLead Sponsor
2,928 Previous Clinical Trials
13,198,333 Total Patients Enrolled
Dieter Manstein, MD, PhDPrincipal Investigator - Massachusetts General Hospital
Dermatology Associate, Massachusetts General Hospital
Westfalische Wilhelms-University (Medical School)
5 Previous Clinical Trials
104 Total Patients Enrolled
Neera Nathan, MD, MSHSPrincipal InvestigatorMassachusetts General Hospital
3 Previous Clinical Trials
69 Total Patients Enrolled
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I am between 18 and 40 years old.My gender and skin type do not limit my participation.Subject must be willing and able to provide written informed consent and comply with the requirements of the study protocol.I cannot use or have chosen not to use standard treatments like oral isotretinoin.I am between 18 and 40 years old.I cannot take or have chosen not to take standard treatments like oral isotretinoin.I am willing to protect my skin from the sun during and for a year after the study.I am currently taking medication for acne.You have had an allergic reaction to numbing creams used for anesthesia in the past.I am using or want to start using skin-applied treatments.I have not taken isotretinoin in the last year.I have not had laser treatment in the last 6 months.I have moderate to severe acne on my face.I am willing to protect my skin from the sun during and for a year after the study.My gender and skin type do not limit my participation.You have a history of raised or thickened scars called keloids or hypertrophic scars.I have a history of wounds healing poorly.
Research Study Groups:
This trial has the following groups:- Group 1: Treatment
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Who else is applying?
What state do they live in?
Massachusetts
Ohio
How old are they?
18 - 65
What site did they apply to?
MGH Clinical Unit for Research Trials & Outcomes in Skin
What portion of applicants met pre-screening criteria?
Met criteria
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