Maxaquin

Blepharitis, Blepharoconjunctivitis, prophylaxis of urinary tract infections + 5 more

Treatment

12 Active Studies for Maxaquin

Treatment for

Blepharitis

What is Maxaquin

LomefloxacinThe Generic name of this drug

Treatment SummaryLomefloxacin is an antibiotic used to treat bacterial infections such as bronchitis and urinary tract infections. It can also be used to help prevent urinary tract infections before surgery.

Maxaquinis the brand name

Maxaquin Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Maxaquin

Lomefloxacin

2006

1

Effectiveness

How Maxaquin Affects PatientsLomefloxacin is an antibiotic used to treat chronic bronchitis and urinary tract infections. It can also be used to prevent urinary tract infections in people undergoing certain procedures. It works well against many types of bacteria, including those that can cause gonorrhea, pneumonia, staph infections, and shigellosis. It is also effective against bacteria that have become resistant to other antibiotics.

How Maxaquin works in the bodyLomefloxacin is a type of antibiotic that kills bacteria. It works by stopping the bacteria from creating new DNA. It does this by targeting two enzymes, DNA gyrase and topoisomerase IV, which are needed to make DNA. When these enzymes are stopped, the bacteria's ability to make new DNA is blocked, leading to its death.

When to interrupt dosage

The recommended dosage of Maxaquin depends upon the diagnosed condition, including Blepharitis, Blepharoconjunctivitis and prophylaxis of urinary tract infections. The amount of dosage is contingent upon the administration approach indicated in the table beneath.

Condition

Dosage

Administration

Blepharitis

400.0 mg,

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet

Blepharoconjunctivitis

400.0 mg,

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet

prophylaxis of urinary tract infections

400.0 mg,

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet

Acute Bacterial Conjunctivitis

400.0 mg,

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet

Transrectal prostate biopsy

400.0 mg,

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet

Operative Surgical Procedures

400.0 mg,

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet

Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)

400.0 mg,

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet

Urinary Tract Infection

400.0 mg,

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet - Oral, Tablet

Warnings

Maxaquin has two contraindications and should not be employed alongside the conditions presented in the following table.Maxaquin Contraindications

Condition

Risk Level

Notes

Toxoplasma Infections

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Lomefloxacin may interact with Toxoplasma Infections

There are 20 known major drug interactions with Maxaquin.

Common Maxaquin Drug Interactions

Drug Name

Risk Level

Description

Amiodarone

Major

The risk or severity of QTc prolongation can be increased when Lomefloxacin is combined with Amiodarone.

Amitriptyline

Major

Lomefloxacin may increase the QTc-prolonging activities of Amitriptyline.

Anagrelide

Major

The risk or severity of QTc prolongation can be increased when Lomefloxacin is combined with Anagrelide.

Arsenic trioxide

Major

The risk or severity of QTc prolongation can be increased when Lomefloxacin is combined with Arsenic trioxide.

Artemether

Major

The risk or severity of QTc prolongation can be increased when Lomefloxacin is combined with Artemether.

Maxaquin Toxicity & Overdose RiskNegative side effects of this drug include tingling or numbness in the hands and feet, nervousness, restlessness, anxiety, and skin irritation or burning when exposed to sunlight.

Maxaquin Novel Uses: Which Conditions Have a Clinical Trial Featuring Maxaquin?

A total of 10 active clinical trials are currently assessing the potential of Maxaquin in treating Blepharitis, Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB) and prophylaxis against Urinary Tract Infections.

Condition

Clinical Trials

Trial Phases

Blepharitis

0 Actively Recruiting

Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)

0 Actively Recruiting

prophylaxis of urinary tract infections

0 Actively Recruiting

Blepharoconjunctivitis

0 Actively Recruiting

Operative Surgical Procedures

0 Actively Recruiting

Acute Bacterial Conjunctivitis

0 Actively Recruiting

Urinary Tract Infection

12 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4

Transrectal prostate biopsy

0 Actively Recruiting

Maxaquin Reviews: What are patients saying about Maxaquin?

1Patient Review

11/9/2007

Maxaquin for Urinary Tract Infection

I had a severe allergic reaction to this medication, characterized by extreme itching all over my body and intense swelling of my face. My throat also swelled up so badly that I needed to use my inhaler. The pharmacist stayed on the phone with me until I took several doses of Benedryl. Please be very careful with this drug - it could have killed me if I had taken a full dose instead of just half.

1Patient Review

3/31/2011

Maxaquin for Bacterial Infection with Chronic Bronchitis

Do not under any circumstances take this drug. I had a reaction so severe that I needed to go to the ER.

Patient Q&A Section about maxaquin

What is nalidixic acid used for?

"Nalidixic acid is a medication used to treat uncomplicated urinary tract infections that is only effective against enteric bacteria." - Anonymous Online Contributor

Unverified Answer

What is sparfloxacin used for?

"Sparfloxacin is an antibiotic that is used to treat bacterial respiratory infections and sinusitis. This drug works by inhibiting DNA gyrase, a bacterial enzyme." - Anonymous Online Contributor

Unverified Answer

What is Pefloxacin tablet used for?

"Pefloxacin is an antibiotic that treats a variety of bacterial infections. It is a synthetic broad-spectrum fluoroquinolone antibacterial agent that is active against most gram-negative and gram-positive bacteria." - Anonymous Online Contributor

Unverified Answer

What is lomefloxacin hydrochloride used for?

"Lomefloxacin is an antibiotic that is used to treat bronchitis, urinary tract infections, and to prevent urinary tract infections in patients who are having surgery." - Anonymous Online Contributor

Unverified Answer

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Clinical Trials for Maxaquin

Image of Magee Women's Hospital of UPMC in Pittsburgh, United States.

Phase-Based Progress Estimates

Empiric Antibioticfor Urinary Tract Infection

This trial will assess if a culture-based or empiric antibiotic strategy is best for treating UTI symptoms in older women, and their ability to follow the study plan.

Magee Women's Hospital of UPMC

Image of Northwestern University in Chicago, United States.

Phase-Based Progress Estimates

Storz Flex-XC1 Disposable Flexible Ureteroscopefor Kidney Stones

This trial tests disposable flexible ureteroscopes to see if they are suitable for medical use.

Northwestern University

Image of Cincinnati Urogynecology Associates in Cincinnati, United States.

Phase-Based Progress Estimates

Silver-Coated Catheterfor Urinary Tract Infection

This trialaims to see if coating a catheter in silver stops urinary tract infections after pelvic surgery.

Cincinnati Urogynecology Associates (+1 Sites)Jennifer Yeung, DO

Image of West Los Angeles VA Medical Center in Los Angeles, United States.

Phase-Based Progress Estimates

Silq Cleartract™ 100% Silicone 2-Way Foley Catheterfor Biofilm Formation

Los Angeles, CA

This trial will compare the Silq ClearTract™ 100% Silicone 2-Way Foley Catheter to other commercially available urinary catheters to see which one reduces biofilm formation better in subjects that require a long-term indwelling Foley catheter.

West Los Angeles VA Medical Center (+5 Sites)Hydrophilix

Have you considered Maxaquin clinical trials? We made a collection of clinical trials featuring Maxaquin, we think they might fit your search criteria.

Explore trials for Maxaquin

Image of Roswell Park Cancer Institute in Buffalo, United States.

Phase-Based Progress Estimates

Trimethoprim-Sulfamethoxazolefor Urinary Tract Infection

This trial is testing whether a month of antibiotics can help reduce urinary infections after surgery to remove the bladder.

FDA Approved Drug

Roswell Park Cancer InstituteKhurshid A Guru

Image of St. Joseph's Health Care London in London, Canada.

Phase-Based Progress Estimates

Pacran And Sapnov P Quillajafor Urinary Tract Infection

This trialwill look at how cranberry and quillaja capsules can help treat urinary tract infections.

St. Joseph's Health Care LondonBlayne Welk, MD

Image of Riverside Community Hospital in Riverside, United States.

Phase-Based Progress Estimates

INSPIRE CPOE Smart Promptfor Urinary Tract Infection

This trial will compare the effects of two different methods of treating UTIs in adults. One method is the standard antibiotic stewardship practices, and the other is a real-time precision medicine computerized physician order entry smart prompts.

Waitlist Available

Riverside Community Hospital (+58 Sites)Richard Platt, MD, MS

Image of University of California, San Diego in San Diego, United States.

Phase-Based Progress Estimates

No Antibioticfor Kidney Stones

This trial will study whether a single dose of Ciprofloxicin, an antibiotic, can prevent infection after ureteral stent removal. The control group will not receive any antibiotics.

FDA Approved Drug

University of California, San Diego

Have you considered Maxaquin clinical trials? We made a collection of clinical trials featuring Maxaquin, we think they might fit your search criteria.

Explore trials for Maxaquin

Image of London Health Sciences Centre in London, Canada.

Phase-Based Progress Estimates

Probiotics Plus Antibioticfor Urinary Tract Infection

This trial will test whether probiotics are safe and can reduce the number of urinary tract infections and the amount of renal scarring in children with neurogenic bladder conditions who are using clean intermittent catheterization.

No Cost For Treatment

London Health Sciences CentreSumit DaveCanadian Urological Association

Image of McMaster Children's Hospital in Hamitlon, Canada.

Phase-Based Progress Estimates

Trimethoprimfor Hydronephrosis

Hamitlon, Canada

This trial looks at whether giving antibiotics to pregnant women who have a fetus with hydronephrosis can help prevent urinary tract infections in the child.

Waitlist Available

FDA Approved Drug

McMaster Children's Hospital (+1 Sites)Luis H Braga, MD, MSc, PhD

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