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What is Maxaquin
LomefloxacinThe Generic name of this drug
Treatment SummaryLomefloxacin is an antibiotic used to treat bacterial infections such as bronchitis and urinary tract infections. It can also be used to help prevent urinary tract infections before surgery.
Maxaquinis the brand name
Maxaquin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Maxaquin
Lomefloxacin
2006
1
Effectiveness
How Maxaquin Affects PatientsLomefloxacin is an antibiotic used to treat chronic bronchitis and urinary tract infections. It can also be used to prevent urinary tract infections in people undergoing certain procedures. It works well against many types of bacteria, including those that can cause gonorrhea, pneumonia, staph infections, and shigellosis. It is also effective against bacteria that have become resistant to other antibiotics.
How Maxaquin works in the bodyLomefloxacin is a type of antibiotic that kills bacteria. It works by stopping the bacteria from creating new DNA. It does this by targeting two enzymes, DNA gyrase and topoisomerase IV, which are needed to make DNA. When these enzymes are stopped, the bacteria's ability to make new DNA is blocked, leading to its death.
When to interrupt dosage
The recommended dosage of Maxaquin depends upon the diagnosed condition, including Blepharitis, Blepharoconjunctivitis and prophylaxis of urinary tract infections. The amount of dosage is contingent upon the administration approach indicated in the table beneath.Condition
Dosage
Administration
Operative Surgical Procedures
, 400.0 mg
Tablet - Oral, Oral, Tablet, , Tablet, film coated, Tablet, film coated - Oral
Blepharitis
, 400.0 mg
Tablet - Oral, Oral, Tablet, , Tablet, film coated, Tablet, film coated - Oral
Acute Bacterial Conjunctivitis
, 400.0 mg
Tablet - Oral, Oral, Tablet, , Tablet, film coated, Tablet, film coated - Oral
Urinary Tract Infection
, 400.0 mg
Tablet - Oral, Oral, Tablet, , Tablet, film coated, Tablet, film coated - Oral
prophylaxis of urinary tract infections
, 400.0 mg
Tablet - Oral, Oral, Tablet, , Tablet, film coated, Tablet, film coated - Oral
Transrectal prostate biopsy
, 400.0 mg
Tablet - Oral, Oral, Tablet, , Tablet, film coated, Tablet, film coated - Oral
Blepharoconjunctivitis
, 400.0 mg
Tablet - Oral, Oral, Tablet, , Tablet, film coated, Tablet, film coated - Oral
Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)
, 400.0 mg
Tablet - Oral, Oral, Tablet, , Tablet, film coated, Tablet, film coated - Oral
Warnings
Maxaquin has two contraindications and should not be employed alongside the conditions presented in the following table.Maxaquin ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Lomefloxacin may interact with Pulse Frequency
Common Maxaquin Drug Interactions
Drug Name
Risk Level
Description
Amiodarone
Major
The risk or severity of QTc prolongation can be increased when Lomefloxacin is combined with Amiodarone.
Amitriptyline
Major
Lomefloxacin may increase the QTc-prolonging activities of Amitriptyline.
Anagrelide
Major
The risk or severity of QTc prolongation can be increased when Lomefloxacin is combined with Anagrelide.
Arsenic trioxide
Major
The risk or severity of QTc prolongation can be increased when Lomefloxacin is combined with Arsenic trioxide.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Lomefloxacin is combined with Artemether.
Maxaquin Toxicity & Overdose RiskNegative side effects of this drug include tingling or numbness in the hands and feet, nervousness, restlessness, anxiety, and skin irritation or burning when exposed to sunlight.
Maxaquin Novel Uses: Which Conditions Have a Clinical Trial Featuring Maxaquin?
A total of 10 active clinical trials are currently assessing the potential of Maxaquin in treating Blepharitis, Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB) and prophylaxis against Urinary Tract Infections.Condition
Clinical Trials
Trial Phases
Blepharitis
0 Actively Recruiting
Blepharoconjunctivitis
0 Actively Recruiting
prophylaxis of urinary tract infections
0 Actively Recruiting
Operative Surgical Procedures
0 Actively Recruiting
Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)
0 Actively Recruiting
Transrectal prostate biopsy
0 Actively Recruiting
Urinary Tract Infection
8 Actively Recruiting
Not Applicable, Phase 4, Phase 3
Acute Bacterial Conjunctivitis
0 Actively Recruiting
Maxaquin Reviews: What are patients saying about Maxaquin?
1Patient Review
11/9/2007 I had a severe allergic reaction to this medication, characterized by extreme itching all over my body and intense swelling of my face. My throat also swelled up so badly that I needed to use my inhaler. The pharmacist stayed on the phone with me until I took several doses of Benedryl. Please be very careful with this drug - it could have killed me if I had taken a full dose instead of just half.
1Patient Review
3/31/2011 Do not under any circumstances take this drug. I had a reaction so severe that I needed to go to the ER.
Patient Q&A Section about maxaquin
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is nalidixic acid used for?
"Nalidixic acid is a medication used to treat uncomplicated urinary tract infections that is only effective against enteric bacteria."
Answered by AI
What is sparfloxacin used for?
"Sparfloxacin is an antibiotic that is used to treat bacterial respiratory infections and sinusitis. This drug works by inhibiting DNA gyrase, a bacterial enzyme."
Answered by AI
What is Pefloxacin tablet used for?
"Pefloxacin is an antibiotic that treats a variety of bacterial infections. It is a synthetic broad-spectrum fluoroquinolone antibacterial agent that is active against most gram-negative and gram-positive bacteria."
Answered by AI
What is lomefloxacin hydrochloride used for?
"Lomefloxacin is an antibiotic that is used to treat bronchitis, urinary tract infections, and to prevent urinary tract infections in patients who are having surgery."
Answered by AI