Lincomycin Hydrochloride

Bacterial Infections

Treatment

2 FDA approvals

0 Active Studies for Lincomycin Hydrochloride

Treatment for

Bacterial Infections

What is Lincomycin Hydrochloride

Lincomycin

The Generic name of this drug

Treatment Summary

Lincomycin is a medication used to treat bacterial infections. It was discovered in Lincoln, Nebraska in the 1960s and was approved by the FDA in 1964. While it is still used to treat some bacterial infections, it has largely been replaced by its more effective derivative, clindamycin.

Lincocin

is the brand name

Lincomycin Hydrochloride Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Lincocin

Lincomycin

1964

Approved as Treatment by the FDA

Lincomycin, also called Lincocin, is approved by the FDA for 2 uses such as Serious Bacterial Infection and Bacterial Infections .

Serious Bacterial Infection

Bacterial Infections

Effectiveness

How Lincomycin Hydrochloride Affects Patients

Lincomycin is an antibiotic produced naturally by bacteria. It works against a range of bacteria, including some Gram-positive and Gram-negative bacteria. It is most effective against Staphylococcus and Streptococcus species. Lincomycin can cause serious skin reactions, diarrhea, and breathing problems. It should be used with caution in elderly people, those with a history of gastrointestinal disease, asthma, or allergies. In addition, it may contain an ingredient that can be dangerous for children. It also may be less effective in people with kidney or liver issues. Taking lincomycin also can lead to

How Lincomycin Hydrochloride works in the body

Lincomycin works by targeting the bacterial ribosome, which helps the bacteria make proteins. It contains two parts that interact with the ribosome; one part sticks while the other can rotate. This rotation helps the drug to bind more tightly to the ribosome and cause an imbalance that stops the bacteria from making proteins. Some bacteria have developed resistance to lincomycin, which is caused by changes to the ribosome that prevent it from binding properly.

When to interrupt dosage

The endorsed measure of Lincomycin Hydrochloride is contingent upon the indicated condition. The dosage fluctuates as per the technique of administration (e.g. Injection, solution or Solution - Intramuscular; Intravenous) specified in the table hereunder.

Condition

Dosage

Administration

Bacterial Infections

, 300.0 mg/mL, 500.0 mg

Injection, solution - Intramuscular; Intravenous; Subconjunctival, Intramuscular; Intravenous; Subconjunctival, Injection, solution, , Oral, Capsule, Capsule - Oral, Solution - Intramuscular; Intravenous, Solution, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous

Warnings

Lincomycin Hydrochloride Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Lincomycin may interact with Pulse Frequency

There are 20 known major drug interactions with Lincomycin Hydrochloride.

Common Lincomycin Hydrochloride Drug Interactions

Drug Name

Risk Level

Description

Vibrio cholerae CVD 103-HgR strain live antigen

Major

The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Lincomycin.

Amineptine

Minor

Lincomycin may increase the neurotoxic activities of Amineptine.

Amisulpride

Minor

Lincomycin may increase the neurotoxic activities of Amisulpride.

Amitriptylinoxide

Minor

Lincomycin may increase the neurotoxic activities of Amitriptylinoxide.

Amperozide

Minor

Lincomycin may increase the neurotoxic activities of Amperozide.

Lincomycin Hydrochloride Toxicity & Overdose Risk

There is limited information about the toxicity of lincomycin. An overdose may cause severe stomach problems, infection, and allergic reactions. Treatment usually involves providing supportive care and treating the symptoms. Dialysis does not reduce the levels of lincomycin in the blood.

Lincomycin Hydrochloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Lincomycin Hydrochloride?

An active trial is currently underway to assess the potential of Lincomycin Hydrochloride to treat Bacterial Infections.

Condition

Clinical Trials

Trial Phases

Bacterial Infections

0 Actively Recruiting

Patient Q&A Section about lincomycin hydrochloride

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is lincomycin an antibiotic?

"Lincomycin is an antibiotic that is used to treat severe bacterial infections in people who cannot use penicillin antibiotics. Lincomycin should only be used for a severe infection."

Answered by AI

What is lincomycin hydrochloride used for?

"This medication is used to treat bacterial infections by stopping the growth of bacteria. This antibiotic can only treat bacterial infections and not viral infections."

Answered by AI

What type of antibiotic is lincomycin?

"and Neisseria gonorrhoeae.

Lincomycin is an antibiotic that is made naturally from a type of bacteria called Streptomyces lincolnensis. Lincomycin is similar to another antibiotic called clindamycin in that it works against infections caused by Gram-positive and Gram-negative bacteria, as well as some other types of organisms."

Answered by AI