Sleep Restriction for Insomnia
Trial Summary
What is the purpose of this trial?
The study is designed to investigate the impact of three nights of sleep restricted to 4 hours per night, on the processing and regulation of emotional information compared to Insomnia Disorder and control. The investigators will address and attempt to answer two questions. (i) How do three nights of reduced sleep or a diagnosis of Insomnia Disorder affect the processing and regulation of emotional information compared to typical, undisturbed sleep? (ii) What overlapping and distinct neural mechanisms are engaged and associated with behavioral effects when attempting to process and regulate emotions in a sleep restricted state or with a clinical diagnosis of Insomnia Disorder? This study will investigate sleep's role in emotion processing and regulation. The findings will help further understanding of the role of sleep in healthy emotional functioning.
Will I have to stop taking my current medications?
Yes, you will need to stop taking any drugs that could affect sleep or cognitive functioning, such as prescription sleeping pills or antidepressants.
Is sleep restriction therapy safe for humans?
How does sleep restriction treatment for insomnia differ from other treatments?
Sleep restriction treatment for insomnia is unique because it involves deliberately limiting the time spent in bed to improve sleep efficiency and reduce insomnia symptoms. Unlike other treatments, it focuses on consolidating sleep by initially restricting sleep time and gradually increasing it as sleep quality improves.34567
Research Team
Janet M Mullington, PhD
Principal Investigator
Beth Israel Deaconess Medical Center
Eligibility Criteria
This trial is for right-handed individuals who can follow the study's rules, avoid alcohol and drugs during the study, and have normal or corrected-to-normal vision. It's not for those using medications affecting sleep or cognition like sleeping pills or antidepressants.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Baseline behavioral ratings to emotional stimuli with and without emotion regulation strategies
Sleep Restriction
Healthy participants are sleep restricted to 4 hours of sleep for 3 consecutive days before participating in an emotion regulation task during fMRI scanning
Follow-up
Participants are monitored for changes in emotional regulation and neural responses after sleep restriction or normal sleep
Treatment Details
Interventions
- Sleep Restriction
Find a Clinic Near You
Who Is Running the Clinical Trial?
Beth Israel Deaconess Medical Center
Lead Sponsor