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Grief Therapy Approaches for Bereaved Parents

Phase 2
Recruiting
Led By Wendy Lichtenthal, PhD
Research Sponsored by Memorial Sloan Kettering Cancer Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age 18 or older
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 10 months
Awards & highlights

Study Summary

This trial will compare how three different types of support programs affect grief and depression symptoms in parents who have lost a child.

Who is the study for?
This trial is for parents in the U.S. who have lost a child to cancer and are experiencing intense grief (with specific grief scores of 30 or above). Participants must be over 18, speak English, and it's been at least 6 months since their loss. They should live in states where the study can legally operate via telepsychology.Check my eligibility
What is being tested?
The study compares three support programs for bereaved parents: Meaning-Centered Grief Therapy, Supportive Counseling, and Enhanced Usual Care. It aims to see how these approaches help with grief and depression symptoms after losing a child to cancer.See study design
What are the potential side effects?
While not typical 'side effects' as seen with medications, participants may experience increased emotional distress when discussing their loss during therapy sessions.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am 18 years old or older.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~10 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 10 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Center for Epidemiologic Studies Depression Scale - Revised (CESD-R)
Prolonged Grief Disorder-13-R (PG-13-R)
Secondary outcome measures
Beck Hopelessness Scale - Short Form (BHS-SF)
Continuing Bonds Scale (CBS)
PROMIS: Global Health Scale (PROMIS-GH)
+4 more

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Cohort 1: Meaning-Centered Grief Therapy/MCGTExperimental Treatment1 Intervention
Participants will consist of parents who have lost a child to a cancer diagnosis within the last 6 months
Group II: Group 3: Enhanced usual care/EUCActive Control1 Intervention
Participants will consist of parents who have lost a child to a cancer diagnosis within the last 6 months
Group III: Group 2: Supportive Psychotherapy /SPActive Control1 Intervention
Participants will consist of parents who have lost a child to a cancer diagnosis within the last 6 months

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Who is running the clinical trial?

Memorial Sloan Kettering Cancer CenterLead Sponsor
1,936 Previous Clinical Trials
588,474 Total Patients Enrolled
1 Trials studying Grief
60 Patients Enrolled for Grief
Wendy Lichtenthal, PhDPrincipal InvestigatorMemorial Sloan Kettering Cancer Center
7 Previous Clinical Trials
863 Total Patients Enrolled
1 Trials studying Grief
172 Patients Enrolled for Grief
Talia Zaider, PhDPrincipal InvestigatorMemorial Sloan Kettering Cancer Center
5 Previous Clinical Trials
1,017 Total Patients Enrolled

Media Library

Enhanced usual care Clinical Trial Eligibility Overview. Trial Name: NCT05142605 — Phase 2
Grief Research Study Groups: Group 3: Enhanced usual care/EUC, Cohort 1: Meaning-Centered Grief Therapy/MCGT, Group 2: Supportive Psychotherapy /SP
Grief Clinical Trial 2023: Enhanced usual care Highlights & Side Effects. Trial Name: NCT05142605 — Phase 2
Enhanced usual care 2023 Treatment Timeline for Medical Study. Trial Name: NCT05142605 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the enrollment figure for this investigation?

"Affirmative. According to clinicaltrials.gov, this research project posted on March 31st 2022 is presently seeking applicants. 415 participants are needed from 3 separate medical centres."

Answered by AI

What are the core goals of this medical experiment?

"This 6-month study will focus primarily on subjects' Prolonged Grief (PG) symptoms. Ancillary goals are to evaluate the Posttraumatic Growth Inventory - Short Form (PTGI-SF), State Trait Anxiety Inventory - Short Form (STAI-SF), and Beck Hopelessness Scale –Short Form (BHS-SF). PTGI-SF examines positive outcomes following stressful life events, STAI assesses both state and trait anxiety with higher scores indicating increased levels of stress, while BHS evaluates participants’ degree of pessimism; a high number implying lack of hope or feeling pessimistic."

Answered by AI

Is this research currently enrolling participants?

"According to clinicaltrials.gov, this medical experiment is currently in recruitment mode. It was first announced on March 31st 2022 and underwent a recent revision as of November 14th 2022."

Answered by AI

Is Meaning-Centered Grief Therapy a safe practice for individuals?

"With some evidence of safety, but no proof yet that it's efficacious, Meaning-Centered Grief Therapy received a score of 2."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Evaluation of Grief Therapy Approaches for Bereaved Parents
2022. "Evaluation of Grief Therapy Approaches for Bereaved Parents". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05142605.
~207 spots leftby May 2026
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