Tinidazole

Giardiasis, Trichomonas Vaginitis, Sexually Transmitted Diseases + 8 more
Treatment
8 FDA approvals
20 Active Studies for Tinidazole

What is Tinidazole

TinidazoleThe Generic name of this drug
Treatment SummaryMetronidazole is an antibiotic used to treat infections caused by certain parasites, including Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia.
Tindamaxis the brand name
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Tinidazole Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Tindamax
Tinidazole
2004
24

Approved as Treatment by the FDA

Tinidazole, commonly known as Tindamax, is approved by the FDA for 8 uses including Trichomonas Vaginitis and Amebiasis .
Trichomonas Vaginitis
Amebiasis
Bacterial Vaginosis (BV)
Giardiasis
Ameboma
Bacterial Vaginosis
Giardiasis
Trichomonas Vaginitis

Effectiveness

How Tinidazole Affects PatientsTinidazole is a medicine used to treat infections caused by protozoa, which are tiny single-celled organisms. Tinidazole has been shown to be effective against the protozoa Trichomonas vaginalis, Giardia duodenalis (also known as G. lamblia), and Entamoeba histolytica. Tinidazole does not seem to affect the bacteria in the vagina that helps protect against infection.
How Tinidazole works in the bodyTinidazole is an antiprotozoal medication. In some parasites, tinidazole is broken down into a toxic free radical that damages the DNA and kills the cell. It is not known exactly how tinidazole works against other parasites, but it is likely similar.

When to interrupt dosage

The proposed measure of Tinidazole is reliant upon the detected illness, for example Urethritis, Sexually Transmitted Diseases and Trichomoniasis. The sum of dosage may differ, in accordance with the delivery strategy (e.g. Tablet, film coated or Tablet, film coated - Oral) depicted in the table beneath.
Condition
Dosage
Administration
Giardiasis
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Sexually Transmitted Diseases
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Ameboma
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Urethritis
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Sexual Assault
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Candidiasis, Vulvovaginal
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Trichomonas Vaginalis Infection
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Mixed Vaginal Infections
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Bacterial Vaginosis
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Trichomonas Vaginitis
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Sexually Transmitted Diseases
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral

Warnings

Tinidazole Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Tinidazole may interact with Pulse Frequency
There are 20 known major drug interactions with Tinidazole.
Common Tinidazole Drug Interactions
Drug Name
Risk Level
Description
Disulfiram
Major
The risk or severity of adverse effects can be increased when Tinidazole is combined with Disulfiram.
Ethanol
Major
The risk or severity of adverse effects can be increased when Tinidazole is combined with Ethanol.
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Tinidazole.
Abacavir
Minor
Tinidazole may decrease the excretion rate of Abacavir which could result in a higher serum level.
Aclidinium
Minor
Tinidazole may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Tinidazole Toxicity & Overdose RiskThere have been no reported overdoses of tinidazole in humans. In animal studies, the toxic dose of tinidazole was found to be greater than 3,600 mg/kg for mice and greater than 2,000 mg/kg for rats when administered orally. When given through the abdominal cavity, the toxic dose of tinidazole was greater than 2,300 mg/kg in mice and greater than 2,000 mg/kg in rats.
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Tinidazole Novel Uses: Which Conditions Have a Clinical Trial Featuring Tinidazole?

11 clinical trials are currently underway to evaluate the potential of Tinidazole to combat Trichomoniasis, Sexually Transmitted Diseases and Trichomonas Vaginalis Infection.
Condition
Clinical Trials
Trial Phases
Sexual Assault
7 Actively Recruiting
Not Applicable
Sexually Transmitted Diseases
30 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 4
Giardiasis
0 Actively Recruiting
Bacterial Vaginosis
6 Actively Recruiting
Not Applicable, Phase 2, Early Phase 1, Phase 1
Trichomonas Vaginitis
2 Actively Recruiting
Phase 2, Not Applicable
Mixed Vaginal Infections
0 Actively Recruiting
Candidiasis, Vulvovaginal
0 Actively Recruiting
Ameboma
0 Actively Recruiting
Urethritis
0 Actively Recruiting
Trichomonas Vaginalis Infection
0 Actively Recruiting
Sexually Transmitted Diseases
0 Actively Recruiting

Tinidazole Reviews: What are patients saying about Tinidazole?

5Patient Review
1/25/2018
Tinidazole for Vaginosis caused by Bacteria
I followed the instructions and didn't have any issues other than a weird metal taste in my mouth. I was told to drink lots of water and that solved the problem. The medication worked perfectly otherwise, though my heartbeat was rapid.
5Patient Review
12/3/2012
Tinidazole for Vaginosis caused by Bacteria
This treatment was fantastic. It really helped me and I'm grateful for it.
4.7Patient Review
7/18/2015
Tinidazole for Infection that causes Diarrhea - Giardiasis
For Giardia, this medication is highly effective. Within hours of a single dose, Tinidazole eradicates the parasite completely. Symptoms ease within 24 hours and patients are back to normal within 48 hours. The only side effect for the single dose treatment is a metallic taste in your mouth for 12-24 hours.
4.7Patient Review
8/5/2021
Tinidazole for Infection that causes Diarrhea - Giardiasis
I've had to take this medication twice now, unfortunately. Both times it's worked very quickly which is great. The first time I didn't experience any side effects, but the second time I got a really bad metallic taste in my mouth and some mild stomach cramping.
4.7Patient Review
12/21/2015
Tinidazole for Vaginosis caused by Bacteria
I had a slight bad taste in my mouth for the two days I needed to take this.. a little loss of appetite but overall that was it. I was sure to take this with a full stomach first thing in the morning, avoided anything acidic and definitely did not drink any alcohol. I think my experience was a good one with this medication.
View All Reviews
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Patient Q&A Section about tinidazole

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is tinidazole same as Flagyl?

"Tinidazole is an antiprotozoal and antibacterial agent that is similar to metronidazole. It has a longer half-life than metronidazole, allowing for a shorter course of therapy."

Answered by AI

How long does it take for tinidazole to work?

"How long does tinidazole take to work? The effect of tinidazole varies depending on the condition being treated and the individual. In general, it takes about two to seven days for the full effect to occur."

Answered by AI

What are the side effects of tinidazole?

"The text explains the symptoms of lead poisoning, which include a sharp, unpleasant metallic taste in the mouth, upset stomach, vomiting, nausea, loss of appetite, constipation, stomach pain or cramps, and headache."

Answered by AI

Is tinidazole A antibiotic?

"Tinidazole is an antibiotic that treats bacterial vaginosis, trichomoniasis, giardiasis, and amebiasis."

Answered by AI

Clinical Trials for Tinidazole

Have you considered Tinidazole clinical trials? We made a collection of clinical trials featuring Tinidazole, we think they might fit your search criteria.
Have you considered Tinidazole clinical trials? We made a collection of clinical trials featuring Tinidazole, we think they might fit your search criteria.
Have you considered Tinidazole clinical trials? We made a collection of clinical trials featuring Tinidazole, we think they might fit your search criteria.
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