Bleph-10

Trachoma, Pink Eye, Conjunctivitis + 1 more
Treatment
3 Active Studies for Bleph-10

What is Bleph-10

SulfacetamideThe Generic name of this drug
Treatment SummaryCiprofloxacin is a medication used to treat skin infections and urinary tract infections. It is an antibiotic that is applied to the skin or taken orally.
Blephamideis the brand name
image of different drug pills on a surface
Bleph-10 Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Blephamide
Sulfacetamide
1961
61

Effectiveness

How Bleph-10 Affects PatientsSulfacetamide is an antibiotic that can stop the growth of many types of bacteria. It works by blocking the bacteria's ability to make certain proteins. Sulfacetamide is usually taken orally, although it is difficult to give this drug through injection because its salts are very alkaline and can irritate the body. It is spread throughout the body and can even reach high levels in fluids around the brain, although it is no longer used to treat meningitis. Unfortunately, it cannot work in areas with pus or other material that blocks its action.
How Bleph-10 works in the bodySulfacetamide works by interfering with the growth of bacteria by blocking a chemical called para-aminobenzoic acid (PABA). This prevents the bacteria from making folic acid, which is necessary for its survival.

When to interrupt dosage

The suggested dose of Bleph-10 is contingent upon the diagnosed condition, including superficial ocular infections, Pink Eye and Trachoma. The extent of dosage also relies on the technique of delivery (e.g. Solution - Ophthalmic or Aerosol, foam) featured in the table below.
Condition
Dosage
Administration
Trachoma
0.1 mg/mg, , 100.0 mg/mL, 0.098 mg/mg, 300.0 mg/mL, 80.0 mg/mL, 0.009 mg/mg, 0.9 mg/mL, 0.09 mg/mg, 1000.0 mg/mL, 10.0 mg/mL, 90.0 mg/mL, 10.0 %, 100.0 mg, 0.01 mg/mg, 0.095 mg/mg, 150.0 mg/mL, 98.0 mg/mL, 0.0286 mg/mg, 0.28 mg/mg, 0.08 mg/mg, 0.05 mg/mg, 0.15 mg/mg, 0.0098 mg/mg
, Ointment - Ophthalmic, Ointment, Ophthalmic, Topical, Suspension, Suspension - Topical, Solution, Cream - Topical, Lotion, Lotion - Topical, Aerosol, foam, Aerosol, foam - Topical, Cream, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid, Swab, Swab - Topical, Liquid - Topical, Solution - Topical, Cloth, Cloth - Topical, Gel, Rinse - Topical, Gel - Topical, Rinse, Kit, Suspension / drops - Ophthalmic, Suspension / drops, Soap, Soap - Topical, Liquid - Ophthalmic, Shampoo - Topical, Emulsion, Emulsion - Topical, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Suspension - Ophthalmic, Shampoo, Kit - Topical, Vaginal, Cream - Vaginal, Lotion / shampoo, Lotion / shampoo - Topical
Pink Eye
0.1 mg/mg, , 100.0 mg/mL, 0.098 mg/mg, 300.0 mg/mL, 80.0 mg/mL, 0.009 mg/mg, 0.9 mg/mL, 0.09 mg/mg, 1000.0 mg/mL, 10.0 mg/mL, 90.0 mg/mL, 10.0 %, 100.0 mg, 0.01 mg/mg, 0.095 mg/mg, 150.0 mg/mL, 98.0 mg/mL, 0.0286 mg/mg, 0.28 mg/mg, 0.08 mg/mg, 0.05 mg/mg, 0.15 mg/mg, 0.0098 mg/mg
, Ointment - Ophthalmic, Ointment, Ophthalmic, Topical, Suspension, Suspension - Topical, Solution, Cream - Topical, Lotion, Lotion - Topical, Aerosol, foam, Aerosol, foam - Topical, Cream, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid, Swab, Swab - Topical, Liquid - Topical, Solution - Topical, Cloth, Cloth - Topical, Gel, Rinse - Topical, Gel - Topical, Rinse, Kit, Suspension / drops - Ophthalmic, Suspension / drops, Soap, Soap - Topical, Liquid - Ophthalmic, Shampoo - Topical, Emulsion, Emulsion - Topical, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Suspension - Ophthalmic, Shampoo, Kit - Topical, Vaginal, Cream - Vaginal, Lotion / shampoo, Lotion / shampoo - Topical
Conjunctivitis
0.1 mg/mg, , 100.0 mg/mL, 0.098 mg/mg, 300.0 mg/mL, 80.0 mg/mL, 0.009 mg/mg, 0.9 mg/mL, 0.09 mg/mg, 1000.0 mg/mL, 10.0 mg/mL, 90.0 mg/mL, 10.0 %, 100.0 mg, 0.01 mg/mg, 0.095 mg/mg, 150.0 mg/mL, 98.0 mg/mL, 0.0286 mg/mg, 0.28 mg/mg, 0.08 mg/mg, 0.05 mg/mg, 0.15 mg/mg, 0.0098 mg/mg
, Ointment - Ophthalmic, Ointment, Ophthalmic, Topical, Suspension, Suspension - Topical, Solution, Cream - Topical, Lotion, Lotion - Topical, Aerosol, foam, Aerosol, foam - Topical, Cream, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid, Swab, Swab - Topical, Liquid - Topical, Solution - Topical, Cloth, Cloth - Topical, Gel, Rinse - Topical, Gel - Topical, Rinse, Kit, Suspension / drops - Ophthalmic, Suspension / drops, Soap, Soap - Topical, Liquid - Ophthalmic, Shampoo - Topical, Emulsion, Emulsion - Topical, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Suspension - Ophthalmic, Shampoo, Kit - Topical, Vaginal, Cream - Vaginal, Lotion / shampoo, Lotion / shampoo - Topical
Acne Vulgaris
0.1 mg/mg, , 100.0 mg/mL, 0.098 mg/mg, 300.0 mg/mL, 80.0 mg/mL, 0.009 mg/mg, 0.9 mg/mL, 0.09 mg/mg, 1000.0 mg/mL, 10.0 mg/mL, 90.0 mg/mL, 10.0 %, 100.0 mg, 0.01 mg/mg, 0.095 mg/mg, 150.0 mg/mL, 98.0 mg/mL, 0.0286 mg/mg, 0.28 mg/mg, 0.08 mg/mg, 0.05 mg/mg, 0.15 mg/mg, 0.0098 mg/mg
, Ointment - Ophthalmic, Ointment, Ophthalmic, Topical, Suspension, Suspension - Topical, Solution, Cream - Topical, Lotion, Lotion - Topical, Aerosol, foam, Aerosol, foam - Topical, Cream, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid, Swab, Swab - Topical, Liquid - Topical, Solution - Topical, Cloth, Cloth - Topical, Gel, Rinse - Topical, Gel - Topical, Rinse, Kit, Suspension / drops - Ophthalmic, Suspension / drops, Soap, Soap - Topical, Liquid - Ophthalmic, Shampoo - Topical, Emulsion, Emulsion - Topical, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Suspension - Ophthalmic, Shampoo, Kit - Topical, Vaginal, Cream - Vaginal, Lotion / shampoo, Lotion / shampoo - Topical

Warnings

Bleph-10 has one counterindication. It should not be utilized when having any of the conditions outlined in the following table.Bleph-10 Contraindications
Condition
Risk Level
Notes
Chronic Kidney Disease (CKD)
Do Not Combine
There are 17 known major drug interactions with Bleph-10.
Common Bleph-10 Drug Interactions
Drug Name
Risk Level
Description
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Sulfacetamide.
Benzylpenicillin
Moderate
Sulfacetamide may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level.
Estetrol
Moderate
The therapeutic efficacy of Estetrol can be decreased when used in combination with Sulfacetamide.
Insulin argine
Moderate
The risk or severity of hypoglycemia can be increased when Sulfacetamide is combined with Insulin argine.
Insulin aspart
Moderate
The risk or severity of hypoglycemia can be increased when Sulfacetamide is combined with Insulin aspart.
Bleph-10 Toxicity & Overdose RiskThe lowest toxic dose of this drug in mice has been found to be 16500mg/kg. Lower doses may cause redness and swelling, nausea, vomiting, headaches, dizziness, and fatigue. At higher doses, patients may become unconscious.
image of a doctor in a lab doing drug, clinical research

Bleph-10 Novel Uses: Which Conditions Have a Clinical Trial Featuring Bleph-10?

29 active trials are currently exploring the possibilities of Bleph-10 in treating Trachoma, Acne and superficial ocular infections.
Condition
Clinical Trials
Trial Phases
Trachoma
1 Actively Recruiting
Phase 4
Acne Vulgaris
2 Actively Recruiting
Phase 1, Phase 2, Early Phase 1
Pink Eye
0 Actively Recruiting
Conjunctivitis
0 Actively Recruiting

Bleph-10 Reviews: What are patients saying about Bleph-10?

5Patient Review
5/10/2011
Bleph-10 for Bacterial Infection of the Eyelid
I had a sinus infection that led to an eye infection. The pus went away after two days, and the redness disappeared after four. I kept using it for seven full days and my eye looks great now. The only downside is that it stings a little bit when I use it.
4.3Patient Review
6/24/2012
Bleph-10 for Pink Eye from Bacterial Infection
I was a little impatient at first because it took a few days to start working, but my pink eye is way better now. It's not as light-sensitive or irritated, and the redness has gone down significantly.
4Patient Review
12/22/2007
Bleph-10 for Chronic and Contagious form of Conjunctivitis - Trachoma
The drops can sting a little bit when you first put them in, but it's nothing compared to how much they help.
3Patient Review
4/7/2009
Bleph-10 for Pink Eye from Bacterial Infection
I just started taking this medication last night. I won't really know how well it works until tomorrow, but I'm hopeful.
2Patient Review
11/25/2014
Bleph-10 for Bacterial Infection of the Eyelid
This is the second eye drop I've tried and it was incredibly irritating. Not only did it burn, but my eye swelled up and felt raw. The more I used it, the worse the symptoms got. After three days, I stopped using it and have had constant blurred vision for two weeks now. Thankfully, I have an appointment with a specialist in a few days.
2Patient Review
9/19/2012
Bleph-10 for Inflammation of Eyelid Edges and the Lining of the Eye
At my doctor's appointment, things seemed to have improved from the past few days. However, after using this treatment as prescribed, I actually feel worse today than I did before. My eyelid is more swollen and sensitive, and I've been experiencing a burning sensation most of the day.
1.3Patient Review
3/20/2009
Bleph-10 for Chronic and Contagious form of Conjunctivitis - Trachoma
Within 24 hours of using this medication, it was clear to me that it was doing nothing to combat the infection. I went back to my doctor and saw a different one who told me he rarely prescribes Bleph for conjunctivitis. He prescribed Tobramycin ophthalmic drops instead.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about bleph-10

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the generic name for Bleph 10?

"Sulfacetamide sodium ophthalmic solution 10% (Bleph-10) is an antibiotic used to treat bacterial infections of the eyes."

Answered by AI

What bacteria does sulfacetamide treat?

"This medication has a wide range of antibacterial activity against different types of bacteria. It is important to take it as prescribed by your doctor in order to get the most benefit."

Answered by AI

What is Bleph 10 used for?

"It will not work for other types of eye infections.

Sulfacetamide is a medication used to treat bacterial eye infections such as conjunctivitis. Sulfacetamide belongs to a class of drugs known as sulfa antibiotics. Sulfacetamide works by stopping the growth of bacteria. This medication only treats bacterial eye infections and will not work for other types of eye infections."

Answered by AI

How do you get prescribed Bleph 10?

"Place one or two drops of the medication into the conjunctival sac of the infected eye(s) every two to three hours at first. As the infection respond, the dosage may be reduced by lengthening the time between doses."

Answered by AI

Clinical Trials for Bleph-10

Image of Medical University of South Carolina in Charleston, United States.

Isotretinoin vs Tetracycline for Acne

Any Age
All Sexes
Charleston, SC
In the effort to find better treatments for Moderate Acne, which often relies on long-term antibiotic use, researchers are exploring alternative options. While Isotretinoin, a Vitamin A derivative, is highly effective for severe acne, its side effects limit its use for milder cases. A recent study from our institution investigated a new approach: weekly Isotretinoin dosing. The results were promising, with acne improvement and no major side effects. This suggests that weekly Isotretinoin could be a successful alternative for moderate acne in both males and females. To validate these findings, investigators propose a randomized controlled trial comparing weekly Isotretinoin to daily Doxycycline over four months. This study could confirm the safety and effectiveness of weekly Isotretinoin, as well as shed light on patient satisfaction, and long-term results compared to standard antibiotics. This research may offer a breakthrough in treating moderate acne while addressing concerns about antibiotic overuse.
Phase < 1
Recruiting
Medical University of South CarolinaAlex Richmond, MD, MSCR
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security