Zinacef

Impetigo, Maxillary Sinusitis, Bacterial Meningitis + 17 more
Treatment
2 FDA approvals
20 Active Studies for Zinacef

What is Zinacef

CefuroximeThe Generic name of this drug
Treatment SummaryCeftriaxone is a broad-spectrum antibiotic used to treat bacterial infections caused by both gram-positive and gram-negative organisms. It is especially effective against gonorrhea and Haemophilus infections, and is resistant to beta-lactamase enzymes.
Zinacefis the brand name
Zinacef Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Zinacef
Cefuroxime
1989
163

Approved as Treatment by the FDA

Cefuroxime, commonly known as Zinacef, is approved by the FDA for 2 uses such as Bacterial Infections and Urinary Tract Infection (UTI) .
Bacterial Infections
Urinary Tract Infection (UTI)

Effectiveness

How Zinacef Affects PatientsCefuroxime is an antibiotic that works by blocking bacteria from forming the walls they need to survive. This makes it a "bactericidal" drug. Cefuroxime has been shown to be effective against many types of bacteria including Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, and Neisseria gonorrhoeae. It is also effective against Borrelia burgdorferi, which is a type of bacteria that causes Lyme disease. Cefuroxime axet
How Zinacef works in the bodyCefuroxime is an antibiotic that works by interfering with the construction of bacteria's cell walls. It binds to proteins inside the cell wall, preventing the cell wall from being built correctly. As a result, the cell wall weakens and breaks apart, leading to the destruction of the bacterial cell.

When to interrupt dosage

The suggested dosage of Zinacef is contingent upon the determined condition, including Gonorrhea, Urinary Tract Infection (UTI) and Bone and Joint Infections. The measure of dosage fluctuates in accordance with the method of administration (e.g. Intravenous or Tablet, film coated) outlined in the table below.
Condition
Dosage
Administration
Otitis Media
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral
Tonsillitis
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral
Animal bite
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral
Maxillary Sinusitis
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral
mild Streptococcal pharyngitis
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral
moderate Streptococcal tonsillitis
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral
Septicemia
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral
Bacterial Infections
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral
Osteomyelitis
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral
Bronchitis, Chronic
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral
Urinary Tract Infection (UTI)
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral
prophylaxis of infection in minor cuts, scrapes, or burns
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral
Urinary Tract Infections
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral
Impetigo
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral
Bacterial Meningitis
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral
moderate Streptococcal pharyngitis
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral
Operative Surgery
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral
Gonorrhea
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral
Lyme Disease
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral
Bronchitis
, 1500.0 mg, 750.0 mg, 7500.0 mg, 750.0 mg/mL, 90.0 mg/mL, 500.0 mg, 250.0 mg, 150.0 mg/mL, 7.5 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 125.0 mg, 125.0 mg/mL, 75000.0 mg, 225000.0 mg, 95.0 mg/mL, 75.0 mg/mL
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Suspension, Suspension - Oral, Powder, for solution, Powder, for solution - Oral, Powder, for solution - Intravenous, Powder, for solution - Intramuscular; Intravenous, Powder, Powder - Oral, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Granule, for suspension, Granule, for suspension - Oral

Warnings

Zinacef Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Zinacef.
Common Zinacef Drug Interactions
Drug Name
Risk Level
Description
Neomycin
Major
The risk or severity of nephrotoxicity can be increased when Cefuroxime is combined with Neomycin.
Tenofovir
Major
Cefuroxime may increase the nephrotoxic activities of Tenofovir.
Tenofovir alafenamide
Major
Cefuroxime may increase the nephrotoxic activities of Tenofovir alafenamide.
Tenofovir disoproxil
Major
Cefuroxime may increase the nephrotoxic activities of Tenofovir disoproxil.
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Cefuroxime.
Zinacef Toxicity & Overdose RiskTaking too much of a cephalosporin can cause an allergic reaction, with symptoms such as rash, a stuffy nose, coughing, a sore throat, and eye irritation. In severe cases, anaphylactic shock may occur. Taking too much of a cephalosporin can also result in irritation of the brain, causing seizures.
image of a doctor in a lab doing drug, clinical research

Zinacef Novel Uses: Which Conditions Have a Clinical Trial Featuring Zinacef?

At present, 146 active clinical trials are being conducted to assess the capability of Zinacef in providing relief from moderate Streptococcal pharyngitis, Bacterial Infections and Animal bite.
Condition
Clinical Trials
Trial Phases
moderate Streptococcal pharyngitis
0 Actively Recruiting
Gonorrhea
0 Actively Recruiting
prophylaxis of infection in minor cuts, scrapes, or burns
0 Actively Recruiting
Maxillary Sinusitis
0 Actively Recruiting
Operative Surgery
75 Actively Recruiting
Phase 3, Not Applicable, Phase 4, Phase 1, Phase 2, Early Phase 1
Septicemia
1 Actively Recruiting
Not Applicable
Tonsillitis
0 Actively Recruiting
Bronchitis, Chronic
0 Actively Recruiting
moderate Streptococcal tonsillitis
0 Actively Recruiting
Bronchitis
2 Actively Recruiting
Not Applicable
Lyme Disease
3 Actively Recruiting
Phase 1, Phase 2, Phase 3, Not Applicable
Bacterial Meningitis
0 Actively Recruiting
Animal bite
0 Actively Recruiting
Otitis Media
0 Actively Recruiting
Impetigo
0 Actively Recruiting
Bacterial Infections
0 Actively Recruiting
mild Streptococcal pharyngitis
0 Actively Recruiting
Urinary Tract Infections
7 Actively Recruiting
Not Applicable, Phase 4
Osteomyelitis
0 Actively Recruiting
Urinary Tract Infection (UTI)
6 Actively Recruiting
Phase 1, Phase 3, Phase 4, Phase 2

Patient Q&A Section about zinacef

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What type of antibiotic is Zinacef?

"This medication is an antibiotic that belongs to a class of drugs called cephalosporins. It works by stopping the growth of bacteria."

Answered by AI

What is Zinacef used for?

"Zinacef is an antibiotic that is used to treat a wide variety of bacterial infections. Zinacef can also be taken before and during certain surgeries to help prevent infection from occurring."

Answered by AI

Is Zinacef a penicillin?

"Cefuroxime is an antibiotic that is chemically similar to penicillin."

Answered by AI

Is cefuroxime a strong antibiotic?

"Do cefuroxime and amoxicillin treat similar types of infection? Both antibiotics are effective for the right scenario, but there are some types of infection where one may be better."

Answered by AI

Clinical Trials for Zinacef

Image of Washington University / Barnes Jewish Hospital in St Louis, United States.

AI-Driven Clinical Decision Support for Surgery

18+
All Sexes
St Louis, MO
20 million patients have surgery in the United States every year, with approximately 1 million of those patients requiring life-saving blood transfusion. Presurgical preparation for transfusion is important to allow for safe and timely transfusion during surgery; however, excessive preparation is unfortunately common, costly, and contributes to blood waste. This study aims to evaluate an intelligent clinical decision support system that helps clinicians prepare blood for patients who are likely to need it, while avoiding excessive preparation for patients who don't, potentially improving patient safety while reducing blood waste and healthcare costs.
Recruiting
Has No Placebo
Washington University / Barnes Jewish Hospital
Image of UPMC Shadyside Hospital in Pittsburgh, United States.

Bright Green Light Therapy for Postoperative Pain

18+
All Sexes
Pittsburgh, PA
This is an unblinded, parallel group randomized controlled trial to evaluate bright green light as an adjunct therapy after surgery at UPMC Shadyside. The primary outcome measure will be pain intensity with secondary outcome measures including opioid requirements, sleep quality, mood, and overall post-operative recovery. Specific aims/hypotheses for this study are as follows: Aim 1: To assess bright green light therapy's potential as a complementary post-operative analgesic strategy in patients recovering from surgery Hypothesis 1: Participants exposed to bright green light, in comparison to dim white (ambient) light, will have improved postoperative pain scores and lower opioid use. Aim 2: To examine the impact of bright green light therapy on patient-centered measures of post-operative recovery that may be related to improved circadian function. Hypothesis 2: Participants exposed to bright green light, in comparison to dim white (ambient) light, will have improved quality of post-operative recovery, enhanced sleep, and reduced anxiety and depression.
Waitlist Available
Has No Placebo
UPMC Shadyside HospitalRebecca Kotcher, MD
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Corticosteroid Injections for Osteoarthritis

18+
All Sexes
Bethesda, MD
The goal of this clinical trial is to find out which type of steroid medicine, when added to a standard pain-control injection during total knee replacement surgery, works best at reducing pain, limiting opioid use, and improving recovery in adults undergoing surgery for severe knee arthritis or injury. The main questions it aims to answer are: Does adding a steroid to the injection improve pain control and reduce opioid use after surgery? Is the newer extended-release steroid (Zilretta) more effective and safer-especially for patients with diabetes-than the traditional steroid (methylprednisolone)? Researchers will compare: Standard pain-control injection alone Standard injection plus methylprednisolone Standard injection plus Zilretta to see which option provides better pain relief, less opioid use, and improved knee function. (Patients with diabetes or prediabetes will only be in the standard injection or Zilretta groups so researchers can study whether Zilretta is safer for blood sugar control.) Participants will: Be randomly assigned to one of the study groups during their total knee replacement surgery Receive the assigned pain-control injection around the knee joint Be followed after surgery to measure: Pain levels Opioid pain medication use Knee movement (range of motion) Whether another procedure (such as manipulation under anesthesia) is needed if the knee becomes too stiff Patient-reported outcome surveys about pain and function
Phase 2 & 3
Waitlist Available
Walter Reed National Military Medical CenterJohn P Cody, MD
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Image of UPMC Magee-Womens Hospital in Pittsburgh, United States.

Catheterization Methods for Postpartum Urinary Problems

18+
All Sexes
Pittsburgh, PA
At least ten percent of patients have postpartum urinary retention or difficulty urinating after birth, which can cause incontinence and other urinary problems long-term. After getting an epidural placed, patients should be numb in their pelvic region. This numbness makes it difficult to feel the need to urinate, so patients need a urinary catheter placed to empty the bladder. Some patients have one catheter placed throughout their labor and others have a catheter placed to empty the bladder then removed every few hours. The investigators are studying whether placing a catheter once or catheterizing multiple times affects the rate of postpartum urinary problems and infection.
Waitlist Available
Has No Placebo
UPMC Magee-Womens HospitalAnna Binstock, MD
Image of University of California, San Francisco in San Francisco, United States.

Trimethoprim-Sulfamethoxazole for Urinary Tract Infections

13 - 29
All Sexes
San Francisco, CA
The goal of this clinical trial is to learn if a common antibiotic called trimethoprim-sulfamethoxazole (TMP-SMX) can help prevent urinary tract infections (UTIs) in children and young adults who recently had a kidney transplant. Most people take TMP-SMX for about 6 months after getting a kidney transplant. In this study, researchers want to see what happens if people keep taking it for 6 more months. The main questions this study is asking are: * Does TMP-SMX lower the number of UTIs in the first year after transplant? * What side effects or problems do participants have while taking TMP-SMX? Researchers will compare TMP-SMX to a placebo (a look-alike pill that does not contain any medication) to see if TMP-SMX works to prevent UTIs. Participants will: * Take either TMP-SMX or a placebo pill by mouth every day for 6 months * Have three visits to touch base with the study team about any issues * Complete short monthly online surveys about any symptoms or side effects * Share blood and urine test results from their regular transplant clinic visits
Phase 4
Waitlist Available
University of California, San FranciscoAlexandra Bicki, MD
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Surface Electromyography for Surgery

No minimum age - 21
All Sexes
Columbus, OH
The investigators are studying a type of technology that is already used called surface electromyography (EMG). This measures and records electrical activity using sensor stickers in a non-invasive way. The purpose of this study is to use a prototype/test surface EMG machine to measure how well regional anesthesia (nerve block) is working. This device is non-invasive and being used for research use as an unapproved medical device. The information may teach us how to give nerve blocks more safely and effectively. Study participation: Subjects having surgery will have the surface EMG sensor stickers placed on their arms or legs before surgery. These will stay on during surgery and for part of recovery. Study visits: The study will consist of 1 visit that starts in the pre-operative area, through the surgery, and for part of recovery time after surgery.
Waitlist Available
Has No Placebo
Nationwide Children's HospitalGrant Heydinger, MD
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