Unasyn

Bites, Human, Animal bite, Bacterial Infections + 14 more
Treatment
8 FDA approvals
20 Active Studies for Unasyn

What is Unasyn

SulbactamThe Generic name of this drug
Treatment SummaryAmpicillin is an antibiotic that comes from a family of drugs called penicillins. It can be taken orally and works against a wide range of bacteria.
Unasynis the brand name
image of different drug pills on a surface
Unasyn Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Unasyn
Sulbactam
1991
92

Approved as Treatment by the FDA

Sulbactam, also known as Unasyn, is approved by the FDA for 8 uses which include Bacterial Infections and Communicable Diseases .
Bacterial Infections
Used to treat Skin and Subcutaneous Tissue Bacterial Infections in combination with Ampicillin
Communicable Diseases
Used to treat Gynaecological infection in combination with Ampicillin
Intraabdominal Infections
Used to treat Intraabdominal Infections in combination with Ampicillin
Gynaecological infection
Used to treat Gynaecological infection in combination with Ampicillin
Abdominal Infection
Used to treat Intraabdominal Infections in combination with Ampicillin
Bacterial Infections
Used to treat Bacterial Infections in combination with Ampicillin
Skin and Subcutaneous Tissue Bacterial Infections
Used to treat Skin and Subcutaneous Tissue Bacterial Infections in combination with Ampicillin
Urinary Tract Infection (UTI)
Used to treat Bacterial Infections in combination with Ampicillin

Effectiveness

How Unasyn Affects PatientsAmpicillin is a type of antibiotic derived from the penicillin family. It is used to treat bacterial infections caused by certain types of bacteria. It works by blocking the bacteria from building a protective wall around themselves, which weakens and kills them. Ampicillin is resistant to the effects of certain beta-lactamases and can be used to treat both gram-positive and gram-negative bacterial infections.
How Unasyn works in the bodyAmpicillin works by attaching to proteins inside bacterial cell walls. This stops the bacteria from building its cell walls, which leads to the bacteria breaking apart. Ampicillin may also block the action of an enzyme that stops the bacteria from breaking apart.

When to interrupt dosage

The measure of Unasyn is contingent upon the diagnosed affliction, including Salmonella, Urinary Tract Infection and perinatal group B streptococcus. The measure of dose shifts, in line with the method of delivery (e.g. Injection, powder, for solution - Intramuscular; Intravenous or Injection, powder, for solution) featured in the table underneath.
Condition
Dosage
Administration
Surgical Wound Infection
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Community Acquired Pneumonia (CAP)
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Communicable Diseases
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Animal bite
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Bacterial Infections
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Intraabdominal Infections
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Bacterial Infections
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Bacterial Infections
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Healthcare-Associated Pneumonia
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Sinusitis
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Bacterial Infections
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Bites, Human
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Bacterial Infections
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Catheter-Related Infections
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Urinary Tract Infection (UTI)
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Postoperative Infections
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Bacterial Endocarditis
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous

Warnings

Unasyn has one adverse reaction. It should not be used when encountering any of the issues enumerated in the following table.Unasyn Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Unasyn.
Common Unasyn Drug Interactions
Drug Name
Risk Level
Description
Acrivastine
Minor
Sulbactam may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Albutrepenonacog alfa
Minor
Sulbactam may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Almasilate
Minor
Sulbactam may decrease the excretion rate of Almasilate which could result in a higher serum level.
Antihemophilic factor (recombinant), PEGylated
Minor
Sulbactam may decrease the excretion rate of Antihemophilic factor (recombinant), PEGylated which could result in a higher serum level.
Antithrombin III human
Minor
Sulbactam may decrease the excretion rate of Antithrombin III human which could result in a higher serum level.
image of a doctor in a lab doing drug, clinical research

Unasyn Novel Uses: Which Conditions Have a Clinical Trial Featuring Unasyn?

67 active studies are currently investigating the potential of Unasyn to alleviate Urinary Tract Infection, Communicable Diseases and Endocarditis.
Condition
Clinical Trials
Trial Phases
Bites, Human
0 Actively Recruiting
Bacterial Infections
0 Actively Recruiting
Catheter-Related Infections
1 Actively Recruiting
Phase 4
Bacterial Infections
0 Actively Recruiting
Community Acquired Pneumonia (CAP)
3 Actively Recruiting
Not Applicable, Phase 1, Phase 3
Bacterial Endocarditis
2 Actively Recruiting
Not Applicable
Intraabdominal Infections
1 Actively Recruiting
Not Applicable
Bacterial Infections
0 Actively Recruiting
Animal bite
0 Actively Recruiting
Surgical Wound Infection
1 Actively Recruiting
Not Applicable
Sinusitis
21 Actively Recruiting
Not Applicable, Early Phase 1, Phase 2, Phase 4, Phase 3
Urinary Tract Infection (UTI)
9 Actively Recruiting
Phase 1, Phase 3, Phase 4, Not Applicable
Bacterial Infections
0 Actively Recruiting
Postoperative Infections
0 Actively Recruiting
Bacterial Infections
0 Actively Recruiting
Healthcare-Associated Pneumonia
1 Actively Recruiting
Not Applicable
Communicable Diseases
0 Actively Recruiting

Unasyn Reviews: What are patients saying about Unasyn?

5Patient Review
11/18/2008
Unasyn for Pneumonia caused by Bacteria
Not only has this helped with my septic arthritis, but the injections have also alleviated the swelling in my hands and feet, as well as the pain in my neck and abdomen. It's a very gentle treatment that I would recommend to others!
5Patient Review
8/8/2013
Unasyn for Cat Bite Wound
This IV antibiotic really saved me when I got bitten. The swelling, fever, and pain were all gone within 48 hours. If you think pills will cut it, you're wrong--this is what you need to do to avoid sepsis.
3.7Patient Review
9/20/2007
Unasyn for Cat Bite Wound
I had to take this intravenously every six hours for a week due to a cat bite. Afterward, I was relieved of the infection but felt very tired.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about unasyn

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Unasyn the same as amoxicillin?

"Do Unasyn and Amoxil treat the same infections? Unasyn and Amoxil are both antibiotics used to treat bacterial infections. Unasyn also contains a beta-lactamase inhibitor."

Answered by AI

Is Augmentin and Unasyn the same?

"Although they are similar, there are some important differences.

Are Augmentin and Unasyn the Same Thing?

No, Augmentin and Unasyn are not the same thing. Augmentin is a combination of amoxicillin and clavulanate, while Unasyn is a combination of ampicillin sodium and sulbactam sodium. Both are used to treat various types of infections, but there are some important differences between the two."

Answered by AI

What is Unasyn used for?

"This medication is used to treat a wide variety of bacterial infections. It is a penicillin-type antibiotic and works by stopping the growth of bacteria."

Answered by AI

What infections does Unasyn treat?

"Meningococcal meningitis is a bacterial infection that causes inflammation of the tissues around the brain and spinal cord. Streptococcus bacterium is the most common cause of meningococcal meningitis. However, other bacteria such as Klebsiella pneumoniae can also cause this disease. Meningococcal meningitis is a serious infection and can be life-threatening. Early diagnosis and treatment are essential for a good outcome."

Answered by AI

Clinical Trials for Unasyn

Have you considered Unasyn clinical trials? We made a collection of clinical trials featuring Unasyn, we think they might fit your search criteria.
Have you considered Unasyn clinical trials? We made a collection of clinical trials featuring Unasyn, we think they might fit your search criteria.
Have you considered Unasyn clinical trials? We made a collection of clinical trials featuring Unasyn, we think they might fit your search criteria.
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