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Procedure

Pain Management Techniques for Total Knee Replacement

N/A

Recruiting

Led By Stavros Memtsoudis, MD/PhD

Research Sponsored by Hospital for Special Surgery, New York

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age 18 to 75 years

Patients with osteoarthritis scheduled for a primary total knee arthroplasty with a participating surgeon

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 3 months & 6 months

Awards & highlights

Study Summary

This trial will compare opioid consumption 24-48 hrs after knee surgery in patients with an adductor canal catheter (ACC) or a sham ACC + ACB. Follow-up for 6 months to check for differences in opioid use and chronic pain.

Who is the study for?

This trial is for adults aged 18-75 with osteoarthritis scheduled for knee replacement surgery at certain surgeons, living within an hour of the hospital, owning a smartphone, and able to follow instructions in English. Excluded are those with general anesthesia, drug allergies, BMI >40, diabetes, severe joint deformity or contracture, chronic opioid or gabapentin use.Check my eligibility

What is being tested?

The study tests if there's a difference in opioid use after surgery between patients getting an adductor canal catheter (ACC) versus a sham catheter. It uses the Diagnotes app for communication and checks pain levels up to 6 months post-surgery.See study design

What are the potential side effects?

Potential side effects may include discomfort at the catheter site, possible infection risk from the catheter placement and side effects related to opioids such as nausea, constipation or drowsiness.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am between 18 and 75 years old.

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I am scheduled for a knee replacement surgery with a participating surgeon due to osteoarthritis.

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I will be receiving regional anesthesia.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 3 months & 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~3 months & 6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 months & 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Opioid consumption at 24-48 hours

Secondary outcome measures

Blinding Assessment

Block complications

Block resolution

+25 more

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Adductor Canal Catheter (ACC) - InterventionalExperimental Treatment1 Intervention

Patients will received the an adductor canal catheter that continuously infuses numbing medication to their operative leg for 50 hours post-surgery. Patients will also communicate with their pain doctor via the Diagnotes application while the catheter is in place.

Group II: Adductor Canal Block (ACB) - ControlPlacebo Group1 Intervention

Patients will received the a sham adductor canal catheter that is attached to their operative leg for 50 hours post-surgery. Patients will also communicate with their pain doctor via the Diagnotes application while the catheter is in place.

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

Hospital for Special Surgery, New YorkLead Sponsor

243 Previous Clinical Trials

59,266 Total Patients Enrolled

Stavros Memtsoudis, MD/PhDPrincipal InvestigatorHospital for Special Surgery, New York

1 Previous Clinical Trials

18 Total Patients Enrolled

Justas Lauzadis, PhDStudy DirectorHospital for Special Surgery, New York

2 Previous Clinical Trials

192 Total Patients Enrolled

Media Library

Adductor Canal Catheter (Procedure) Clinical Trial Eligibility Overview. Trial Name: NCT05981105 — N/A

Total Knee Replacement Clinical Trial 2023: Adductor Canal Catheter Highlights & Side Effects. Trial Name: NCT05981105 — N/A

Adductor Canal Catheter (Procedure) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05981105 — N/A

Total Knee Replacement Research Study Groups: Adductor Canal Block (ACB) - Control, Adductor Canal Catheter (ACC) - Interventional

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does the recruitment criteria encompass those aged eighty-five and above?

"This clinical trial is available to adults between 18 and 75 years of age. There are 54 studies for minors, while 480 studies target elderly patients."

Answered by AI

Does this clinical trial have open vacancies?

"The search for participants is in full force, according to the clinicaltrials.gov data. This inquiry was initiated on June 12th 2023 and most recently updated July 31st of that same year."

Answered by AI

Is my profile compatible with the criteria for this research endeavor?

"In order to meet the qualifications for this study, potential participants must be suffering from chronic pain and have an age between 18 and 75. As of now, 64 patients are being sought by the research team."

Answered by AI

What is the cohort size for this research endeavor?

"Affirmative. The details on clinicaltrials.gov demonstrate that this clinical trial is currently enrolling participants, with an initial posting date of June 12th 2023 and a most recent modification on July 31st 2023. This trial seeks to recruit 64 individuals from 1 site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Enhanced Recovery After Major Surgery and Chronic Pain for Total Knee Arthroplasty

2023. "Enhanced Recovery After Major Surgery and Chronic Pain for Total Knee Arthroplasty". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05981105.

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