← Back to Search

Vaccine

Flu Shot for Elderly Individuals

N/A

Recruiting

Led By Sean Leng

Research Sponsored by Johns Hopkins University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Adults over age 75 years

Be older than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up at the end of the study-5th year

Awards & highlights

Study Summary

This trial is being done to study the immune system in older people and to find out if the Flu Shot is effective in them.

Who is the study for?

This trial is for adults over the age of 75, regardless of their health status. It's not suitable for those on cancer treatments, with egg or vaccine allergies, active cancers, inability to consent, acute heart/lung conditions exacerbations, or taking steroids/immune-modifying drugs.Check my eligibility

What is being tested?

The study tests how well people over 75 respond to the flu shot and if chronic CMV infection affects this response. Participants will receive a free flu shot and undergo health assessments including blood draws before and after vaccination.See study design

What are the potential side effects?

While the flu shot is generally safe for elderly individuals, some may experience mild side effects such as soreness at injection site, low-grade fever, muscle aches or fatigue shortly after receiving it.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am over 75 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ at the end of the study-5th year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~at the end of the study-5th year

This trial's timeline: 3 weeks for screening, Varies for treatment, and at the end of the study-5th year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Presence of CMV Viral DNA in Peripheral Blood Monocytes

Secondary outcome measures

Immune Responses to High Dose TIV Immunization

Other outcome measures

Effectiveness of High Dose TIV Immunization

Influence of Frailty and Chronic CMV Infection on Vaccine-Induced Influenza Strain-Specific Antibody Titers and T-Cell Responses

Trial Design

1Treatment groups

Experimental Treatment

Group I: Influenza ImmunizationExperimental Treatment1 Intervention

Influenza immunization in adults over age 75

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Influenza

2016

N/A

~1300

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

Johns Hopkins UniversityLead Sponsor

2,263 Previous Clinical Trials

14,822,140 Total Patients Enrolled

1 Trials studying Immunizations

225 Patients Enrolled for Immunizations

Sean LengPrincipal InvestigatorJohns Hopkins University

Media Library

Influenza (Vaccine) Clinical Trial Eligibility Overview. Trial Name: NCT02200276 — N/A

Immunizations Research Study Groups: Influenza Immunization

Immunizations Clinical Trial 2023: Influenza Highlights & Side Effects. Trial Name: NCT02200276 — N/A

Influenza (Vaccine) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02200276 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many individuals are enrolled in this research endeavor?

"Affirmative. According to the clinicaltrials.gov records, 525 participants are needed at one medical site for this trial - which was initially posted on March 1st 2014 and recently revised on March 14th 2022."

Answered by AI

Is enrollment for this experiment open at present?

"Clinicaltrials.gov affirms the active recruitment of patients for this medical study, which was initially posted on March 1st 2014 and recently updated on March 14th 2022."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Influenza Immunization in Adults Over Age 75

2014. "Influenza Immunization in Adults Over Age 75". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02200276.

All > Flu