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Vitamin

Vitamin C for Acute Pain

N/A

Recruiting

Led By Raoul Daoust, MD MSc

Research Sponsored by Hopital du Sacre-Coeur de Montreal

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Discharged with an opioid prescription

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 3 months

Awards & highlights

Study Summary

This trial aims to study whether taking vitamin C can reduce the amount of opioid pills needed for pain relief in patients discharged from the emergency department with acute musculoskeletal pain. The study will compare the use

Who is the study for?

This trial is for adults over 18 who visited the emergency department (ED) with musculoskeletal pain that's been there for less than two weeks. They must have left the ED with a prescription for opioids and be able to speak French or English.Check my eligibility

What is being tested?

The study tests if taking vitamin C reduces opioid use after an ED visit for acute musculoskeletal pain. Participants will either receive 1000 mg of vitamin C twice daily or a placebo, over two weeks, and track their opioid intake and pain levels.See study design

What are the potential side effects?

Vitamin C is generally considered safe but can sometimes cause digestive issues like heartburn, stomach cramps, nausea, or diarrhea at high doses.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I was prescribed opioids when I was discharged.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 3 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~3 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Contraceptives, Oral

Secondary outcome measures

Average pain relief

Limb structure

Incidence of chronic pain (including complex regional pain syndrome (CRPS)) globally and for each type of MSK pain

+4 more

Side effects data

From 2018 Phase 2 trial • 20 Patients • NCT03148236

10%

Pericarditis

100%

80%

60%

40%

20%

Study treatment Arm

Vitamin C

Placebo

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Vitamin CExperimental Treatment1 Intervention

1 000 mg vitamin C taken orally twice a day

Group II: PlaceboPlacebo Group1 Intervention

Matching placebo

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Vitamin C

2017

Completed Phase 4

~18470

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

Hopital de l'Enfant-JesusOTHER

16 Previous Clinical Trials

5,358 Total Patients Enrolled

2 Trials studying Acute Pain

2,786 Patients Enrolled for Acute Pain

Hopital du Sacre-Coeur de MontrealLead Sponsor

51 Previous Clinical Trials

11,805 Total Patients Enrolled

3 Trials studying Acute Pain

3,547 Patients Enrolled for Acute Pain

Raoul Daoust, MD MScPrincipal InvestigatorUniversité de Montréal

3 Previous Clinical Trials

3,547 Total Patients Enrolled

3 Trials studying Acute Pain

3,547 Patients Enrolled for Acute Pain

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are participants currently being recruited for this clinical trial?

"As documented on clinicaltrials.gov, this investigation is presently seeking eligible participants. Initially shared on November 1st, 2023, the last revision was made on February 23rd, 2024."

Answered by AI

What is the total number of individuals actively engaged in this medical study?

"Indeed, the details on clinicaltrials.gov indicate that this investigation is presently enrolling participants. Initially shared on November 1st, 2023, and last revised on February 23rd, 2024, this study aims to recruit a total of 464 patients at a single site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Impact of Vitamin C on opioïd Consumption After an Emergency Department Visit for Acute Musculoskeletal Pain

Raoul Daoust 2023. "Impact of Vitamin C on opioïd Consumption After an Emergency Department Visit for Acute Musculoskeletal Pain". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05555576.

All > Acute Pain