Exercise for Type 2 Diabetes
Trial Summary
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but it excludes participants who are taking certain medications like vasoactive drugs. If you're on medications like metformin or GLP-1 agonists, you must have been on them for at least a year to participate.
What data supports the effectiveness of the treatment Exercise, Physical Activity, Workout, Fitness Training for Type 2 Diabetes?
Research shows that regular exercise can significantly improve blood sugar control, reduce the risk of heart problems, and enhance overall health in people with Type 2 diabetes. Exercise is as effective as some medications in managing diabetes, and combining aerobic and resistance exercises can maximize these benefits.12345
Is exercise safe for people with type 2 diabetes?
Exercise is generally safe for people with type 2 diabetes if certain precautions are taken, such as monitoring glucose levels and considering individual health conditions like diabetic foot or cardiovascular risks. It's important to adapt exercise routines to each person's needs and consult healthcare providers to minimize the risk of injury or adverse events.678910
How does exercise as a treatment for type 2 diabetes differ from other treatments?
Exercise is unique for type 2 diabetes because it is a non-drug treatment that improves insulin sensitivity and glycemic control, reduces body fat, and enhances cardiovascular fitness. Unlike medications, exercise requires regular physical activity to maintain its benefits and can be tailored to individual needs, making it a flexible and cost-effective option.911121314
What is the purpose of this trial?
Extracellular vesicles (EVs) play a role in obesity-induced insulin resistance and likely impact the development of cardiovascular disease. However, little is known on how EVs affect vascular insulin action in people. The purpose of this study is to understand how EVs play a role in type 2 diabetes related cardiovascular disease. This research will also study if exercise can change how EVs impact blood flow and metabolic health. This study will contribute to designing precision medicine to treat/prevent cardiovascular disease in type 2 diabetes.
Research Team
Steven K Malin, PhD
Principal Investigator
Rutgers University - New Brunswick
Eligibility Criteria
This trial is for individuals with Type 2 Diabetes and obesity, aiming to understand how extracellular vesicles (EVs) affect cardiovascular disease related to diabetes. Participants should be interested in how exercise might influence their blood flow and metabolic health.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo supervised exercise training sessions at 85% VO2max, expending approximately 400 kcal per session
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Exercise
Find a Clinic Near You
Who Is Running the Clinical Trial?
Rutgers, The State University of New Jersey
Lead Sponsor
University of Virginia
Collaborator
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator