Xibrom

Eye Pain, Cataract Surgery, Conjunctivitis

Treatment

5 FDA approvals

3 Active Studies for Xibrom

What is Xibrom

Bromfenac

The Generic name of this drug

Treatment Summary

Bromfenac is an eye medication used to reduce eye pain and inflammation. It belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs) and is commonly used in surgery to help improve outcomes. It is known to provide good pain relief and has a good safety record.

Xibrom

is the brand name

Xibrom Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Xibrom

Bromfenac

2005

19

Approved as Treatment by the FDA

Bromfenac, otherwise called Xibrom, is approved by the FDA for 5 uses including Conjunctivitis and Ocular Inflammation .

Conjunctivitis

Ocular Inflammation

Eye

Helps manage Eye Pain

Eye Pain

Helps manage Eye Pain

Cataract Surgery

Helps manage Cataract Surgery

Effectiveness

How Xibrom Affects Patients

Bromfenac ophthalmic solution is an eye drop that contains a non-steroid anti-inflammatory drug (NSAID). It is used to reduce inflammation in the eyes.

How Xibrom works in the body

Acetazolamide works by blocking the production of prostaglandins, which are inflammatory molecules. In animal studies, prostaglandins have been shown to cause swelling, leakage of blood vessels, and increased pressure in the eye. Blocking their production can reduce these effects.

When to interrupt dosage

The measure of Xibrom is contingent upon the identified disorder, including Cataract Surgery, Eye Pain and Ocular Inflammation. The amount likewise differs according to the technique of delivery (e.g. Solution / drops - Ophthalmic or Solution / drops) featured in the table beneath.

Condition

Dosage

Administration

Cataract Surgery

, 0.9 mg/mL, 1.035 mg/mL, 0.07 %, 0.7 mg/mL, 0.76 mg/mL, 0.75 mg/mL

, Solution / drops - Ophthalmic, Ophthalmic, Solution / drops, Solution - Ophthalmic, Solution, Suspension / drops - Ophthalmic, Suspension / drops

Eye Pain

, 0.9 mg/mL, 1.035 mg/mL, 0.07 %, 0.7 mg/mL, 0.76 mg/mL, 0.75 mg/mL

, Solution / drops - Ophthalmic, Ophthalmic, Solution / drops, Solution - Ophthalmic, Solution, Suspension / drops - Ophthalmic, Suspension / drops

Conjunctivitis

, 0.9 mg/mL, 1.035 mg/mL, 0.07 %, 0.7 mg/mL, 0.76 mg/mL, 0.75 mg/mL

, Solution / drops - Ophthalmic, Ophthalmic, Solution / drops, Solution - Ophthalmic, Solution, Suspension / drops - Ophthalmic, Suspension / drops

Warnings

Xibrom has one noted contraindication, and it should not be taken for the circumstances in the ensuing table.

Xibrom Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

There are 20 known major drug interactions with Xibrom.

Common Xibrom Drug Interactions

Drug Name

Risk Level

Description

Valproic acid

Minor

The protein binding of Valproic acid can be decreased when combined with Bromfenac.

Aceclofenac

Moderate

The risk or severity of adverse effects can be increased when Bromfenac is combined with Aceclofenac.

Acemetacin

Moderate

The risk or severity of adverse effects can be increased when Bromfenac is combined with Acemetacin.

Acetylsalicylic acid

Moderate

The therapeutic efficacy of Acetylsalicylic acid can be decreased when used in combination with Bromfenac.

Alclofenac

Moderate

The risk or severity of adverse effects can be increased when Bromfenac is combined with Alclofenac.

Xibrom Novel Uses: Which Conditions Have a Clinical Trial Featuring Xibrom?

Currently, 7 investigations are examining the potential of Xibrom to offer relief from Cataract Surgery, Eye Pain and Ocular Inflammation.

Condition

Clinical Trials

Trial Phases

Eye Pain

0 Actively Recruiting

Cataract Surgery

3 Actively Recruiting

Not Applicable

Conjunctivitis

0 Actively Recruiting

Patient Q&A Section about xibrom

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the generic name for bromfenac?

"A generic version of bromfenac (Prolensa) is available and may be much cheaper than the brand version."

Answered by AI

What is bromfenac 0. 09% used for?

"Bromday can be used to treat inflammation and pain in the eye for patients who have had cataract surgery."

Answered by AI

What is xibrom used for?

"Xibrom is a prescription medication used to treat the symptoms of Cataract Postoperative Ocular Inflammation or Pain. It may be used alone or with other medications. Xibrom belongs to a class of drugs called Ophthalmic NSAIDs."

Answered by AI

Is there a generic for PROLENSA?

"It is important to note that there is no generic equivalent to the drug PROLENSA if you are prescribed the medication after having cataract surgery. If your pharmacist requests that you substitute your PROLENSA prescription for another medication, you should reach out to your eye doctor."

Answered by AI

Clinical Trials for Xibrom

Image of Byers Eye Institute in Palo Alto, United States.

LLM-Based Education for Cataract Surgery

18+
All Sexes
Palo Alto, CA

Patients with cataracts disease need to choose what type of artificial lens will go into their eye prior to surgery date. Some lenses are standard and are usually covered by insurance. Other "premium" lenses have various benefits such as reducing the need for glasses but usually require out-of-pocket costs. The combined busy outpatient clinic and complexity of artificial lens choices in the ever-changing world of cataract surgery tends to lead patients confused about their available lens options. There is an abundance of educational material present in premium lenses, however these are limited by accessibility and are standardized at single educational levels. Therefore in the present study, we want to test whether giving patients a short LLM powered AI-guided explanation from Custom GPT from OpenAI of lens options prior to their consultation with their doctor can improve visit efficiency, physician explanation and patient understanding of lens options. We will compare two groups: standard of care versus standard of care plus AI education. The LLM in this study is intended to provide supplemental information about premium intraocular lens(IOLs) options to study participants, and is no means supposed to replace a health care professional in the diagnosis, cure, treatment, and/or mitigation of disease. Study is analogous to giving a verified health pamphlet to a patient for them to view and learn different IOL options, in other words, facilitating patient understanding of their options. The LLM will be trained by several health care professionals and MD specialists to provide sufficient instructions. Sources will include verified online resources and MD information. The investigators hope to learn if a large language model-based educational tool can improve visit efficiency, physician explanation and patient understanding of intraocular lens options. New knowledge of this study could guide how cataract counseling is delivered in the future and may help clinics spend more time on individualized questions instead of repeating generic information.

Waitlist Available
Has No Placebo

Byers Eye Institute

Robert T Chang, MD

Image of University of California, San Francisco in San Francisco, United States.

Vision Centers for Eye Care

Any Age
All Sexes
San Francisco, CA

The goal of this clinical trial is to evaluate the effect of vision centers on access to eye care and eye health outcomes in South Asia. The main questions it aims to answer are: 1. Do vision centers increase visits to eyecare centers? 2. Do vision centers increase spectacle ownership and wearing? 3. Do vision centers improve visual acuity of the population? Researchers will compare outcomes in communities randomized to have a vision center is established with communities randomized to delay establishment of a vision center. Outcomes will be assessed through population-based surveys at baseline and after two years as well as through hospital records collected throughout the study period.

Waitlist Available
Has No Placebo

University of California, San Francisco

Kieran O'Brien, PhD, MPH