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What is Zioptan
TafluprostThe Generic name of this drug
Treatment SummaryTafluprost is a medication that is used in eye drops to treat glaucoma and high eye pressure. It works by decreasing the amount of fluid in the eye, which helps to relieve pressure. Tafluprost was approved by the FDA in 2012 and is a chemical analogue of the hormone prostaglandin F2-alpha.
Zioptanis the brand name
Zioptan Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Zioptan
Tafluprost
2012
7
Approved as Treatment by the FDA
Tafluprost, also known as Zioptan, is approved by the FDA for 3 uses which include Open Angle Glaucoma and Increased Intra Ocular Pressure (IOP) .Open Angle Glaucoma
Helps manage Open Angle Glaucoma (OAG)
Increased Intra Ocular Pressure (IOP)
Helps manage Increased Intra Ocular Pressure (IOP)
Ocular Hypertension
Helps manage Ocular Hypertension
Effectiveness
How Zioptan Affects PatientsTafluprost is a new type of drug that attaches itself to the FP receptor PGF2α. It binds to this receptor 12 times more strongly than latanoprost, but does not attach to any other receptors.
How Zioptan works in the bodyTafluprost acid is a drug that helps reduce pressure in the eye. It works by increasing the outflow of fluid from the eye, allowing pressure to be relieved.
When to interrupt dosage
The suggested dosage of Zioptan is contingent upon the identified circumstance, for instance Increased Intra Ocular Pressure (IOP), Open Angle Glaucoma and Open Angle Glaucoma. The measure of dosage differs, as per the method of delivery described in the subsequent table.Condition
Dosage
Administration
Open-angle glaucoma
, 0.045 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic
Ocular Hypertension
, 0.045 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic
Open Angle Glaucoma
, 0.045 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic
Increased Intra Ocular Pressure (IOP)
, 0.045 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic
Warnings
Zioptan ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Common Zioptan Drug Interactions
Drug Name
Risk Level
Description
Bimatoprost
Moderate
The therapeutic efficacy of Bimatoprost can be decreased when used in combination with Tafluprost.
Zioptan Toxicity & Overdose RiskThe most common side effect of the eyes is redness in the whites of the eyes (occurring in 4-20% of cases).
Zioptan Novel Uses: Which Conditions Have a Clinical Trial Featuring Zioptan?
114 active trials are being conducted to evaluate the potential of Zioptan to manage Ocular Hypertension, Increased Intra Ocular Pressure (IOP) and Open Angle Glaucoma.Condition
Clinical Trials
Trial Phases
Open Angle Glaucoma
12 Actively Recruiting
Not Applicable, Phase 3, Phase 2
Increased Intra Ocular Pressure (IOP)
0 Actively Recruiting
Open-angle glaucoma
84 Actively Recruiting
Phase 3, Not Applicable, Phase 1, Phase 2, Phase 4, Early Phase 1
Ocular Hypertension
22 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 3, Phase 4
Zioptan Reviews: What are patients saying about Zioptan?
5Patient Review
9/3/2022 This medication has been working great for me in reducing the pressure in my eyes. I haven't really noticed any negative side effects, except maybe with my balance, but I understand that can be a problem as we get older.
4.3Patient Review
6/23/2013 This medication was very effective in lowering my blood pressure, without any adverse effects. The only downside is that you can't use one vial for more than one day, and they're a bit pricey since there's no generic yet.
4Patient Review
8/21/2014 My doctor says this drug is perfect for me, as it doesn't contain any preservatives (to which I'm allergic). The downside is that it can cause dryness and a burning sensation. However, it has lowered my pressure beautifully.
4Patient Review
12/20/2018 I've only been taking this medication for a week, but it has already worked better for me than many other medications I have tried in the past. My eyes are red, but there is no pain or itching.
3.7Patient Review
7/31/2012 I've been using this product for a while now, and I haven't experienced any negative side effects. Additionally, there are no preservatives in Zioptan which means that there is no eye redness like with the Lumigen drop. However, you have to keep the drops refrigerated.
3.7Patient Review
2/8/2015 I experienced a number of bothersome side effects while taking this medication. These included a racing heart, shortness of breath, and stuffiness in my nasal passages. Additionally, I suffered from dry eyes, blurry vision, and dry throat/chapped lips. This was all within 6 months of starting the medication, and ultimately caused me to develop cataracts in both eyes.
3.3Patient Review
6/22/2012 This medication caused my eyes to become red and irritated, as well as giving me headaches and sinus irritation.
3.3Patient Review
8/27/2012 The dry cough and eye redness are manageable, but the heart palpitations are a bit concerning.
3Patient Review
1/9/2013 I experienced some heart palpitations and redness in my eyes. I also felt very dizzy.
3Patient Review
2/4/2015 I've been on this medication for a little over a month and a half now, and I'm still experiencing lightheadedness and palpations. Has anyone else experienced this? How long did it last for you?
3Patient Review
2/15/2015 I've been experiencing sinus congestion, neck pain, and throbbing headaches for two months now. I was hoping the side effects would go away with time, but unfortunately that hasn't been the case.
2.7Patient Review
11/27/2013 I was disappointed that this didn't do more to lower my eye pressure.
2.3Patient Review
7/28/2013 I tried this treatment for a week and had some bad side effects like sleeplessness and indigestion. I wouldn't recommend it.
2.3Patient Review
5/3/2022 Within three days of taking this medication, I began to experience lightening-like flashes in my eye. Additionally, a large floater appeared. However, the worst symptom by far was the vitreous gel pulling away from my eyeball which caused even more floaters, severe headaches, eye pain, blurred distance vision, and light sensitivity. This stuff is horrible and if it's truly preservative-free like they claim, then there must be something else in it that is causing all these problems.
2.3Patient Review
3/4/2013 I developed iritis, an inflammation of the iris, after the second dose. The pain was unbearable; it felt like someone was constantly stabbing my eye with an ice pick. I also had a severe headache and became extremely sensitive to light. My co-workers said I looked like a vampire because of all the redness.
2.3Patient Review
10/29/2013 I'm choosing to discontinue this medication after only seven days due to thestuffiness in my nose which has gotten worse each day, as well as fatigue, light flashes, and dry eyes.
2.3Patient Review
1/23/2013 I have headaches, blurred vision and flashes of light when I first put the drop in. I have been on Zioptan for close 11 month to year
2Patient Review
3/2/2022 My eyes felt very irritated after using this treatment. They were red and itchy, and I also experienced increased watering and sensitivity to light.
Patient Q&A Section about zioptan
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Zioptan used for?
"Tafluprost is used to treat high pressure inside the eye due to open-angle glaucoma or other eye diseases, such as ocular hypertension. By regulating the flow of fluid within the eye, tafluprost can help prevent blindness."
Answered by AI
Is Zioptan preservative free?
"Once a container of ZIOPTAN is opened, it can no longer be considered sterile. Any solution that is not used should be discarded immediately. ZIOPTAN can be used at the same time as other topical ophthalmic drugs to lower intraocular pressure."
Answered by AI
What is the cost of Zioptan without insurance?
"How much does Zioptan cost without insurance?
The normal retail cost of Zioptan without health insurance is $276.96 per 1, 30 Solution Solution. However, you can get a discount by using a SingleCare Zioptan coupon to pay only $183.52 for 1, 30 Solution Plas Cont of generic Zioptan."
Answered by AI
What is the generic name for Zioptan?
"At the moment, there is no cheaper generic version of Zioptan (tafluprost). However, there are some other alternatives available, such as latanoprost (Xalatan) and bimatoprost (Lumigan), which are generic medications. When it comes to Zioptan (tafluprost), how long does it take for it to work?"
Answered by AI