Cialis

Enlarged Prostate, Impotence, Pulmonary Arterial Hypertension
Treatment
5 FDA approvals
20 Active Studies for Cialis

What is Cialis

TadalafilThe Generic name of this drug
Treatment SummaryTadalafil is a medication used to treat erectile dysfunction, pulmonary arterial hypertension, and an enlarged prostate. It was approved by the FDA in 2003 for ED and in 2009 for PAH. Compared to other similar medications, tadalafil has a longer lasting effect which makes it suitable for treating chronic conditions like PAH with a single daily dose.
Cialisis the brand name
image of different drug pills on a surface
Cialis Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Cialis
Tadalafil
2003
295

Approved as Treatment by the FDA

Tadalafil, commonly known as Cialis, is approved by the FDA for 5 uses including Pulmonary Arterial Hypertension (PAH) and Erectile dysfunction .
Pulmonary Arterial Hypertension (PAH)
Helps manage Pulmonary Arterial Hypertension (PAH)
Erectile dysfunction
Helps manage Erectile Dysfunction
Impotence
Helps manage Erectile Dysfunction
Pulmonary Arterial Hypertension
Helps manage Pulmonary Arterial Hypertension (PAH)
Enlarged Prostate

Effectiveness

How Cialis Affects PatientsTadalafil helps treat ED by stimulating the blood flow to the penis, allowing it to become erect. It can also help with pulmonary arterial hypertension (PAH) by widening the blood vessels, and with benign prostatic hyperplasia (BPH) by reducing the size of the prostate. Tadalafil has a lower risk of causing visual side effects than other PDE5 inhibitors.
How Cialis works in the bodyTadalafil is a drug that helps muscles relax, decreasing pressure and allowing more blood to flow. It has many applications, but is most commonly used to treat erectile dysfunction, pulmonary arterial hypertension, and benign prostatic hyperplasia. For erectile dysfunction, tadalafil blocks a protein that breaks down a compound that helps muscles relax. This process allows muscles to relax in the penis, filling with blood to create an erection. For pulmonary arterial hypertension, it works similarly, by allowing more blood to flow and decreasing pressure in the pulmonary arteries. For benign prostatic hyperplasia, the effect is less clear,

When to interrupt dosage

The dosage of Cialis is contingent upon the determined malady, such as Impotence, Pulmonary Arterial Hypertension and Enlarged Prostate. The dosage can be found in the table beneath, based on the approach of delivery (e.g. Tablet, film coated - Oral or Tablet).
Condition
Dosage
Administration
Enlarged Prostate
, 10.0 mg, 20.0 mg, 5.0 mg, 2.5 mg, 40.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated - Oral, Tablet, coated, Capsule - Oral, Capsule
Pulmonary Arterial Hypertension
, 10.0 mg, 20.0 mg, 5.0 mg, 2.5 mg, 40.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated - Oral, Tablet, coated, Capsule - Oral, Capsule
Impotence
, 10.0 mg, 20.0 mg, 5.0 mg, 2.5 mg, 40.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated - Oral, Tablet, coated, Capsule - Oral, Capsule

Warnings

Cialis Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Cialis.
Common Cialis Drug Interactions
Drug Name
Risk Level
Description
Alprostadil
Major
The risk or severity of hypotension and priapism can be increased when Tadalafil is combined with Alprostadil.
Amifostine
Major
Tadalafil may increase the hypotensive activities of Amifostine.
Amyl Nitrite
Major
The risk or severity of hypotension can be increased when Tadalafil is combined with Amyl Nitrite.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Tadalafil.
Avanafil
Major
The risk or severity of adverse effects can be increased when Tadalafil is combined with Avanafil.
Cialis Toxicity & Overdose RiskOverdosing on Tadalafil can lead to symptoms such as headaches, indigestion, back pain, muscle aches, congestion, and dizziness. Standard medical treatments should be used to treat the overdose, and hemodialysis is not expected to help remove the drug from the bloodstream.
image of a doctor in a lab doing drug, clinical research

Cialis Novel Uses: Which Conditions Have a Clinical Trial Featuring Cialis?

95 active studies are currently assessing the potential of Cialis to treat Impotence, Pulmonary Arterial Hypertension and Enlarged Prostate conditions.
Condition
Clinical Trials
Trial Phases
Impotence
15 Actively Recruiting
Not Applicable, Phase 4, Early Phase 1, Phase 3, Phase 1, Phase 2
Pulmonary Arterial Hypertension
3 Actively Recruiting
Phase 1, Not Applicable, Phase 4
Enlarged Prostate
16 Actively Recruiting
Not Applicable, Phase 2

Cialis Reviews: What are patients saying about Cialis?

5Patient Review
12/24/2020
Cialis for Inability to have an Erection
I used to have occasional issues which led to low confidence. I tried 20mg of [drug] but it gave me a headache for three days straight. After doing some research, I started taking cialis 2.5mg daily and haven't had any side effects. I'm really happy with the results and would highly recommend it to others.
5Patient Review
10/23/2021
Cialis for Enlarged Prostate with Urination Problems
I can finally empty my bladder completely when I use this medication, which is a huge relief.
5Patient Review
12/16/2021
Cialis for Inability to have an Erection
I had no issues whatsoever after taking this medication. I was able to get and maintain an erection for the duration of intercourse without any problems.
5Patient Review
10/20/2022
Cialis for Inability to have an Erection
I've been using Cialis as needed, and the results have been amazing. I'm finally feeling confident again. Just a few seconds is all it takes for me to get hard, and it lasts for almost 36 hours! My head gets very big and sensitive during this time.
5Patient Review
11/9/2022
Cialis for Inability to have an Erection
I was really pleased with this product. My husband and I were both happy with the results.
4.3Patient Review
2/1/2022
Cialis for Inability to have an Erection
Helped me maintain an erection throughout the day and during activities. Orgasms seemed more intense, which was great!
4.3Patient Review
3/26/2021
Cialis for Inability to have an Erection
The most important part of this review is that, for me, the drug was most effective at a dosage of 10 mg per day. Additionally, it can take several days for the full effects to be felt, so consistency is key.
2.7Patient Review
2/8/2021
Cialis for Inability to have an Erection
I am a 75 year old male in good physical condition. I tried taking 20 mg of this drug an hour before sexual activity. While it did produce somewhat of an erection, only about 75%, the backache that resulted was fairly severe and lasted for days afterward. I'm going to try a smaller dosage of maybe 5mg on a daily basis to see if there's any difference. Worth trying despite my urologist's claims to the contrary.
2Patient Review
3/14/2021
Cialis for Inability to have an Erection
Though this treatment worked for me as an individual, it was a waste of money because my wife saw no change in her own sexual desire.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about cialis

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What does Cialis do for a man?

"Cialis works by increasing the effects of one of the chemicals that the body normally releases into the penis during sexual arousal. This increase in blood flow into the penis causes an erection."

Answered by AI

Does Cialis give you a hard on?

"Cialis helps to increase the effects of a natural chemical in the body that is responsible for sexual arousal. This leads to an increase in blood flow to the penis, resulting in an erection."

Answered by AI

Does Cialis Work as well as Viagra?

"The difference between Viagra and Cialis is that Viagra lasts for 4 to 6 hours while Cialis can last up to 36 hours."

Answered by AI

How long does it take for Cialis to work?

"When used as directed, Cialis typically starts to work within 30 to 60 minutes. Its effects can last up to 36 hours, but you'll only get an erection if you're aroused during that time."

Answered by AI

What are the dangers of taking Cialis?

"The most common side effects of Cialis are headaches, indigestion, back pain, muscle aches, flushing, and a stuffy or runny nose. These side effects usually go away after a few hours. Men who experience back pain and muscle aches usually notice it 12 to 24 hours after taking Cialis."

Answered by AI

Clinical Trials for Cialis

Image of Clinical Physiology Laboratory in Edmonton, Canada.

Sotatercept for Pulmonary Arterial Hypertension

18+
All Sexes
Edmonton, Canada
The goal of this clinical trial is to determine whether sotatercept is effective in improving diffusing capacity in patients with pulmonary arterial hypertension. Participants will be asked to: * Take Sotatercept every 21 days (±3 days) * Each participant will be enrolled in the study for 29 Weeks * Visit the clinic 18 times * Have a physical exam * Perform assessments of lung function and exercise tests * Have an ultrasound of their heart * Have blood draws done at regular intervals The main objectives of the study are: Primary objective: To assess whether sotatercept will improve recruitment of diffusing membrane capacity (DM) with exercise. Secondary objective: To identify components of the diffusing capacity that respond to treatment with sotatercept in pulmonary arterial hypertension.
Phase 4
Recruiting
Clinical Physiology LaboratoryMichael Stickland, PhDMerck Canada Inc.
Have you considered Cialis clinical trials? We made a collection of clinical trials featuring Cialis, we think they might fit your search criteria.Go to Trials
Image of Centre Hospitalier de l'université de Montréal (CHUM) in Montréal, Canada.

Optilume vs Rezum for Enlarged Prostate

18+
Male
Montréal, Canada
Lower urinary symptoms (LUTS) affect older men and their frequency and severity increase with age. According to Berry et al., the histological diagnosis of benign prostatic hyperplasia (BPH) increases from 25% in the group age between 40 to 49 years to 80% in the group age between 70 to 79 years (1). However, this hyperplasia can lead to a bladder outlet obstruction (BOO) secondary to benign prostatic enlargement (BPE), causing storage and voiding symptoms, associated with a considerable impairment of the quality of life (2). Surgical therapy of BPH has continuously evolved in recent years. The current gold standard for the endoscopic treatment of BPH is the transurethral resection of the prostate (TURP). Other innovative techniques were developed including Urolift, transurethral laser enucleation (holmium, thulium) and Aquablation therapy. One of the latest technologies for the management of BPH are Optilume BPH Catheter System (Optilume®, Urotronic Inc, Minneapolis, USA) and Rezum Water Vapor Therapy (Rezum System, Bostocn Scientific, Marlborough, MA). The purpose of the present study is to compare between patient experience, symptom relief and functional improvement when using the Optilume BPH Catheter System (Optilume®, Urotronic Inc, Minneapolis, USA) and Rezum Water Vapor Therapy (Rezum System, Boston Scientific, Marlborough, MA).
Recruiting
Has No Placebo
Centre Hospitalier de l'université de Montréal (CHUM) (+1 Sites)Naeem Bhojani, MD
Have you considered Cialis clinical trials? We made a collection of clinical trials featuring Cialis, we think they might fit your search criteria.Go to Trials
Have you considered Cialis clinical trials? We made a collection of clinical trials featuring Cialis, we think they might fit your search criteria.Go to Trials
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