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Massage Therapy for Peripheral Neuropathy

N/A

Waitlist Available

Led By Gabriel Lopez

Research Sponsored by M.D. Anderson Cancer Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

All gastrointestinal malignancies where the patient received oxaliplatin for cancer treatment or breast malignancies where patients have received docetaxel or paclitaxel for cancer treatment

Lower extremity neuropathy per patient report attributable to oxaliplatin, docetaxel or paclitaxel (neurotoxic chemotherapeutic agent) as determined by patient history of neurotoxic agent administration and no history of other attributable causes such as diabetic neuropathy

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 10 weeks

Awards & highlights

Study Summary

This trial studies whether massage therapy can help reduce symptoms of nerve problems caused by chemotherapy in patients with gastrointestinal or breast cancer.

Who is the study for?

This trial is for English-speaking patients who have had gastrointestinal or breast cancer and received specific chemotherapy drugs, causing nerve problems. They must be stable on current neuropathy medications and able to visit the MD Anderson Main Campus in Texas. Pregnant women, those with low blood counts, a history of deep vein thrombosis within the last year, diabetes, or other causes of neuropathy are excluded.Check my eligibility

What is being tested?

The study is testing if massage therapy can help reduce nerve pain and improve life quality for patients who developed peripheral neuropathy from chemotherapy treatments for gastrointestinal or breast cancers. It involves regular visits to receive massages and completing questionnaires about their symptoms.See study design

What are the potential side effects?

Massage therapy is generally safe but may include temporary discomfort at the site of massage, mild bruising, fatigue after sessions, allergic reactions to oils or lotions used (if any), and rarely aggravation of underlying conditions.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have had oxaliplatin for gastrointestinal cancer or docetaxel/paclitaxel for breast cancer.

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I have nerve pain in my legs due to chemotherapy with oxaliplatin, docetaxel, or paclitaxel.

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I experience significant nerve pain or discomfort.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ at 10 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~at 10 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and at 10 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Completion Rates of Two Massage Treatment Protocols for Patients With Chronic, Oxaliplatin-Induced Peripheral Neuropathy

Secondary outcome measures

Baseline treatment expectations

Function and balance

Quality and intensity of neuropathic pain

+2 more

Trial Design

4Treatment groups

Experimental Treatment

Group I: Group IV (head/neck/shoulder massage 2 x weekly for 6 weeks)Experimental Treatment3 Interventions

Patients undergo massage therapy over 30 minutes to the head, neck, and shoulder twice weekly for 6 weeks.

Group II: Group III (head/neck/shoulder massage 3 x weekly for 4 weeks)Experimental Treatment3 Interventions

Patients undergo massage therapy over 30 minutes to the head, neck, and shoulder thrice weekly for 4 weeks.

Group III: Group II (leg massage 2 x weekly for 6 weeks)Experimental Treatment3 Interventions

Patients undergo massage therapy over 30 minutes to the affected legs at the foot and toes, ending at the knee, twice weekly for 6 weeks.

Group IV: Group I (leg massage 3 x weekly for 4 weeks)Experimental Treatment3 Interventions

Patients undergo massage therapy over 30 minutes to the affected legs at the foot and toes, ending at the knee, thrice weekly for 4 weeks.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Massage Therapy

2012

Completed Phase 2

~840

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

M.D. Anderson Cancer CenterLead Sponsor

2,966 Previous Clinical Trials

1,804,691 Total Patients Enrolled

National Cancer Institute (NCI)NIH

13,654 Previous Clinical Trials

40,933,063 Total Patients Enrolled

Gabriel LopezPrincipal InvestigatorM.D. Anderson Cancer Center

1 Previous Clinical Trials

30 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any opportunities to join the research cohort currently available?

"The information found on clinicaltrials.gov confirms that this medical study, posted in April 2015 and last updated February 2022, is no longer actively seeking participants. However, there are still 4779 other trials recruiting patients at the moment."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Massage Therapy in Reducing Chemotherapy-Induced Peripheral Neuropathy in Patients With Gastrointestinal or Breast Malignancies

2015. "Massage Therapy in Reducing Chemotherapy-Induced Peripheral Neuropathy in Patients With Gastrointestinal or Breast Malignancies". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02221700.

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