Edex

Schizophrenia, Agitation, Sedation + 3 more
Treatment
20 Active Studies for Edex

What is Edex

DexmedetomidineThe Generic name of this drug
Treatment SummaryLoperamide is an antidiarrheal medication that is not absorbed into the body and has no impact on the nervous system. It can block histamine and prevent the release of acetylcholine in the gut, which helps to reduce diarrhea.
Precedexis the brand name
image of different drug pills on a surface
Edex Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Precedex
Dexmedetomidine
2004
83

Effectiveness

How Edex Affects PatientsLoperamide is a medication used to treat diarrhea. It works by slowing down movement in the digestive system, absorbing more fluids, and making stool thicker. It also helps to reduce fecal volume and tighten the anal sphincter, which can help reduce incontinence and improve bowel control. Generally, loperamide will take about an hour to start working, and its effects can last up to three days. While it typically does not cause pain relief, very high doses of loperamide may cross the blood-brain barrier and cause opioid effects. At very high levels, loperamide can interfere with the heart's electrical signals
How Edex works in the bodyLoperamide works by blocking opioid receptors in the intestine. This stops nerve signals from being sent and reduces the release of chemicals like acetylcholine and prostaglandins. As a result, your intestine absorbs more water and slows down the movement of food through the intestines, making your stools dryer and harder.

When to interrupt dosage

The recommended measure of Edex is subject to the specified circumstance, including Diarrhea, Crohn's Disease and Ulcerative Colitis and Intestinal stoma leak. The measure of dosage can be found in the subsequent table, contingent upon the method of administration.
Condition
Dosage
Administration
Schizophrenia
, 0.1 mg/mL, 0.004 mg/mL, 0.1 mg, 0.02 mg/mL, 0.2 mg/mL, 0.18 mg, 0.12 mg
, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Film, Sublingual, Film - Sublingual
Behcet Syndrome
, 0.1 mg/mL, 0.004 mg/mL, 0.1 mg, 0.02 mg/mL, 0.2 mg/mL, 0.18 mg, 0.12 mg
, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Film, Sublingual, Film - Sublingual
Syndrome
, 0.1 mg/mL, 0.004 mg/mL, 0.1 mg, 0.02 mg/mL, 0.2 mg/mL, 0.18 mg, 0.12 mg
, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Film, Sublingual, Film - Sublingual
Agitation
, 0.1 mg/mL, 0.004 mg/mL, 0.1 mg, 0.02 mg/mL, 0.2 mg/mL, 0.18 mg, 0.12 mg
, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Film, Sublingual, Film - Sublingual
Sedation
, 0.1 mg/mL, 0.004 mg/mL, 0.1 mg, 0.02 mg/mL, 0.2 mg/mL, 0.18 mg, 0.12 mg
, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Film, Sublingual, Film - Sublingual
induction of Sedation
, 0.1 mg/mL, 0.004 mg/mL, 0.1 mg, 0.02 mg/mL, 0.2 mg/mL, 0.18 mg, 0.12 mg
, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Film, Sublingual, Film - Sublingual

Warnings

There are 20 known major drug interactions with Edex.
Common Edex Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Dexmedetomidine.
Aminophylline
Major
The metabolism of Aminophylline can be decreased when combined with Dexmedetomidine.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Dexmedetomidine.
Anagrelide
Major
The metabolism of Anagrelide can be decreased when combined with Dexmedetomidine.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Dexmedetomidine.
Edex Toxicity & Overdose RiskA toxic dose of loperamide in rats is 185mg/kg. Taking doses of loperamide much higher than the recommended dose can lead to dangerous heart problems, like abnormal heart rhythms, fainting, heart attack, and even death. Loperamide overdose can also cause side effects such as confusion, poor coordination, sleepiness, pupil constriction, muscle tension, trouble breathing, and reduced movement of the intestines. Naloxone can be used to reverse the effects of loperamide overdose.
image of a doctor in a lab doing drug, clinical research

Edex Novel Uses: Which Conditions Have a Clinical Trial Featuring Edex?

Currently, 52 trials are underway to determine the potential of Edex in providing relief from Chronic Functional Diarrhea, Intestinal stoma leak and Gastroenteritis.
Condition
Clinical Trials
Trial Phases
Schizophrenia
108 Actively Recruiting
Phase 3, Not Applicable, Early Phase 1, Phase 4, Phase 2, Phase 1
Sedation
2 Actively Recruiting
Not Applicable, Phase 1
Agitation
4 Actively Recruiting
Phase 3, Phase 2, Not Applicable
Syndrome
4 Actively Recruiting
Phase 2, Phase 3, Not Applicable
induction of Sedation
0 Actively Recruiting
Behcet Syndrome
1 Actively Recruiting
Not Applicable

Edex Reviews: What are patients saying about Edex?

5Patient Review
6/24/2012
Edex for Inability to have an Erection
Not only did this work well, but it was also much less expensive than the alternatives my doctor prescribed.
5Patient Review
1/4/2015
Edex for Inability to have an Erection
I have diabetes, so I'm used to injecting myself. This was an easy and certain way of overcoming my ED. Three times a week was ample for me.
5Patient Review
2/21/2017
Edex for Inability to have an Erection
This drug has been a game changer for me.
5Patient Review
2/6/2014
Edex for Maintain the Patency of Ductus Arteriosus
I was really disappointed with this drug. I didn't see any results after taking the recommended dosage two times. I'm going to try a higher dose and see if that makes a difference, but I'm not holding my breath.
5Patient Review
1/28/2012
Edex for Inability to have an Erection
Worked well in a urologist office, but not at home.
View All Reviews
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Patient Q&A Section about edex

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How much does edex cost in US?

"Edex ALPROSTADIL is a medication used to treat erectile dysfunction. This medicine helps a person to maintain an erection. The average retail price for Edex is $235.77, but it can be found for as low as $200.85."

Answered by AI

What is edex?

"EdX is a nonprofit online learning platform that was founded by Harvard University and the Massachusetts Institute of Technology. It partners with universities and companies from all around the world to offer interactive and self-paced courses."

Answered by AI

How do you inject edex?

"Make sure to follow your doctor's orders exactly and only administer the prescribed dose. You should not use edex® more than three times a week. Injections should be given at least twenty-four hours apart. Ideally, the injection should be given just before sexual activity."

Answered by AI

How long does an edex erection last?

"If either is present, do not use the liquid.

The liquid form of this medication should work within 5 to 20 minutes to produce an erection lasting for about 1 hour. The manufacturer recommends using it no more than 3 times a week, with at least 1 day between each dose. Check product visually for particles or discoloration before using. If either is present, do not use."

Answered by AI

Clinical Trials for Edex

Have you considered Edex clinical trials? We made a collection of clinical trials featuring Edex, we think they might fit your search criteria.
Have you considered Edex clinical trials? We made a collection of clinical trials featuring Edex, we think they might fit your search criteria.
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