Edex

Schizophrenia, Agitation, Sedation + 3 more
Treatment
20 Active Studies for Edex

What is Edex

DexmedetomidineThe Generic name of this drug
Treatment SummaryLoperamide is an antidiarrheal medication that is not absorbed into the body and has no impact on the nervous system. It can block histamine and prevent the release of acetylcholine in the gut, which helps to reduce diarrhea.
Precedexis the brand name
image of different drug pills on a surface
Edex Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Precedex
Dexmedetomidine
2004
83

Effectiveness

How Edex Affects PatientsLoperamide is a medication used to treat diarrhea. It works by slowing down movement in the digestive system, absorbing more fluids, and making stool thicker. It also helps to reduce fecal volume and tighten the anal sphincter, which can help reduce incontinence and improve bowel control. Generally, loperamide will take about an hour to start working, and its effects can last up to three days. While it typically does not cause pain relief, very high doses of loperamide may cross the blood-brain barrier and cause opioid effects. At very high levels, loperamide can interfere with the heart's electrical signals
How Edex works in the bodyLoperamide works by blocking opioid receptors in the intestine. This stops nerve signals from being sent and reduces the release of chemicals like acetylcholine and prostaglandins. As a result, your intestine absorbs more water and slows down the movement of food through the intestines, making your stools dryer and harder.

When to interrupt dosage

The recommended measure of Edex is subject to the specified circumstance, including Diarrhea, Crohn's Disease and Ulcerative Colitis and Intestinal stoma leak. The measure of dosage can be found in the subsequent table, contingent upon the method of administration.
Condition
Dosage
Administration
Schizophrenia
, 0.1 mg/mL, 0.004 mg/mL, 0.1 mg, 0.02 mg/mL, 0.2 mg/mL, 0.18 mg, 0.12 mg
, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Film, Sublingual, Film - Sublingual
Behcet Syndrome
, 0.1 mg/mL, 0.004 mg/mL, 0.1 mg, 0.02 mg/mL, 0.2 mg/mL, 0.18 mg, 0.12 mg
, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Film, Sublingual, Film - Sublingual
Syndrome
, 0.1 mg/mL, 0.004 mg/mL, 0.1 mg, 0.02 mg/mL, 0.2 mg/mL, 0.18 mg, 0.12 mg
, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Film, Sublingual, Film - Sublingual
Agitation
, 0.1 mg/mL, 0.004 mg/mL, 0.1 mg, 0.02 mg/mL, 0.2 mg/mL, 0.18 mg, 0.12 mg
, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Film, Sublingual, Film - Sublingual
Sedation
, 0.1 mg/mL, 0.004 mg/mL, 0.1 mg, 0.02 mg/mL, 0.2 mg/mL, 0.18 mg, 0.12 mg
, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Film, Sublingual, Film - Sublingual
induction of Sedation
, 0.1 mg/mL, 0.004 mg/mL, 0.1 mg, 0.02 mg/mL, 0.2 mg/mL, 0.18 mg, 0.12 mg
, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Film, Sublingual, Film - Sublingual

Warnings

There are 20 known major drug interactions with Edex.
Common Edex Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Dexmedetomidine.
Aminophylline
Major
The metabolism of Aminophylline can be decreased when combined with Dexmedetomidine.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Dexmedetomidine.
Anagrelide
Major
The metabolism of Anagrelide can be decreased when combined with Dexmedetomidine.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Dexmedetomidine.
Edex Toxicity & Overdose RiskA toxic dose of loperamide in rats is 185mg/kg. Taking doses of loperamide much higher than the recommended dose can lead to dangerous heart problems, like abnormal heart rhythms, fainting, heart attack, and even death. Loperamide overdose can also cause side effects such as confusion, poor coordination, sleepiness, pupil constriction, muscle tension, trouble breathing, and reduced movement of the intestines. Naloxone can be used to reverse the effects of loperamide overdose.
image of a doctor in a lab doing drug, clinical research

Edex Novel Uses: Which Conditions Have a Clinical Trial Featuring Edex?

Currently, 52 trials are underway to determine the potential of Edex in providing relief from Chronic Functional Diarrhea, Intestinal stoma leak and Gastroenteritis.
Condition
Clinical Trials
Trial Phases
Schizophrenia
98 Actively Recruiting
Phase 3, Not Applicable, Early Phase 1, Phase 4, Phase 1, Phase 2
Sedation
2 Actively Recruiting
Early Phase 1, Not Applicable
Agitation
3 Actively Recruiting
Phase 2, Phase 3, Not Applicable
Syndrome
4 Actively Recruiting
Phase 2, Phase 3, Not Applicable
induction of Sedation
0 Actively Recruiting
Behcet Syndrome
1 Actively Recruiting
Not Applicable

Edex Reviews: What are patients saying about Edex?

5Patient Review
6/24/2012
Edex for Inability to have an Erection
Not only did this work well, but it was also much less expensive than the alternatives my doctor prescribed.
5Patient Review
1/4/2015
Edex for Inability to have an Erection
I have diabetes, so I'm used to injecting myself. This was an easy and certain way of overcoming my ED. Three times a week was ample for me.
5Patient Review
2/21/2017
Edex for Inability to have an Erection
This drug has been a game changer for me.
5Patient Review
2/6/2014
Edex for Maintain the Patency of Ductus Arteriosus
I was really disappointed with this drug. I didn't see any results after taking the recommended dosage two times. I'm going to try a higher dose and see if that makes a difference, but I'm not holding my breath.
5Patient Review
1/28/2012
Edex for Inability to have an Erection
Worked well in a urologist office, but not at home.
4.7Patient Review
2/22/2017
Edex for Inability to have an Erection
I'm really pleased with this treatment. I was a bit nervous about using it at first, but it's been great.
4.7Patient Review
8/23/2012
Edex for Inability to have an Erection
I've been using this for about eighteen months now, since my prostate surgery. It works around 60% of the time, which is definitely better than nothing. I tried pills before this and they did absolutely nothing for me.
4.7Patient Review
7/5/2013
Edex for Inability to have an Erection
I had great results with this treatment and didn't experience any negative side effects.
4.7Patient Review
4/25/2014
Edex for Inability to have an Erection
I was really impressed with how quickly this worked. I had an erection in no time and it lasted for quite a while. The only downside is that it can cause some overall pain, but that seems to be getting better the more I use it.
4.3Patient Review
11/13/2012
Edex for Inability to have an Erection
Always gets me excited. The main issue I have is that there's some loss of sensation, which makes it difficult to orgasm sometimes. My wife enjoys it, though.
4.3Patient Review
12/26/2019
Edex for Inability to have an Erection
I'm 66, and I've been using Edex for over a year. I think my penis size has modestly increased during that time? After prostate surgery left me with a permanently flaccid penis, I was desperate to find a solution. Edex (20mg) completely changed my life. Erections last 180 minutes each time, followed by 30 minutes to slowly subside. Has anyone else experienced an increase in penis size from regular use of Edex?
4Patient Review
2/4/2013
Edex for Inability to have an Erection
This didn't quite meet my expectations.
3Patient Review
3/20/2021
Edex for Inability to have an Erection
The 20mg dose doesn't seem to last very long, especially if I'm lying down.
2.7Patient Review
1/29/2014
Edex for Inability to have an Erection
I've been using EDEX for a while now, and it's been great. I always get really hard erections, which is amazing compared to when I was a teenager. They usually last for an hour or so, but sometimes I don't orgasm at all. Not sure if that's the EDEX or not, but either way it's still pretty good
2.3Patient Review
9/19/2012
Edex for Maintain the Patency of Ductus Arteriosus
Viagra made me feel faint and Cialis was unreliable, but this medication worked great for me. Only ten minutes after injection, I had a full erection that lasted awhile. It's a bit pricey, though I have heard from other users that you can get a cheaper version of this mixture from your pharmacist.
1.7Patient Review
2/15/2011
Edex for Inability to have an Erection
1.3Patient Review
9/25/2013
Edex for Inability to have an Erection
Finding the right dosage was a bit of a trial and error, but once I found that 15mcg worked great for me this medication became much more effective.
1Patient Review
5/10/2011
Edex for Inability to have an Erection
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about edex

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How much does edex cost in US?

"Edex ALPROSTADIL is a medication used to treat erectile dysfunction. This medicine helps a person to maintain an erection. The average retail price for Edex is $235.77, but it can be found for as low as $200.85."

Answered by AI

What is edex?

"EdX is a nonprofit online learning platform that was founded by Harvard University and the Massachusetts Institute of Technology. It partners with universities and companies from all around the world to offer interactive and self-paced courses."

Answered by AI

How do you inject edex?

"Make sure to follow your doctor's orders exactly and only administer the prescribed dose. You should not use edex® more than three times a week. Injections should be given at least twenty-four hours apart. Ideally, the injection should be given just before sexual activity."

Answered by AI

How long does an edex erection last?

"If either is present, do not use the liquid.

The liquid form of this medication should work within 5 to 20 minutes to produce an erection lasting for about 1 hour. The manufacturer recommends using it no more than 3 times a week, with at least 1 day between each dose. Check product visually for particles or discoloration before using. If either is present, do not use."

Answered by AI

Clinical Trials for Edex

Image of The University of Iowa in Iowa City, United States.

fMRI for Cognitive Flexibility

18 - 35
All Sexes
Iowa City, IA
The goal of this basic experimental research study is to examine how the human thalamus supports flexible thinking and behavior. Specifically, the research aims to elucidate how the mediodorsal (MD) thalamus encodes and updates "context"-the mental framework that determines which rules or actions are relevant in a given situation. This work may contribute to understanding why certain psychiatric conditions, such as schizophrenia and ADHD, involve difficulties with cognitive flexibility and control. The primary research questions are: Does the MD thalamus represent the context that organizes how working memory guides task selection? Does the MD thalamus signal when context needs to be updated after a change in task demands? Do these thalamic representations support generalization to new situations or rules? Participants will complete cognitive tasks while undergoing high-resolution brain imaging using 7-Tesla MRI. The investigators will combine behavioral data, computational modeling, and advanced neuroimaging analyses to examine how the thalamus interacts with the cortex during flexible decision-making.
Waitlist Available
Has No Placebo
The University of Iowa
Image of Vanderbilt Psychiatric Hospital in Nashville, United States.

Repetitive Transcranial Magnetic Stimulation for Schizophrenia

18 - 65
All Sexes
Nashville, TN
The central hypothesis is this: DMN connectivity can be modulated with inhibitory cTBS when delivered on an accelerated treatment schedule. This study seeks to provide evidence that accelerated, network-targeted inhibitory stimulation of the DMN leads to both altered network activity and a concomitant behavioral change in cognitive performance in individuals with schizophrenia and schizoaffective disorder. This study will also compare the effect of inhibitory cTBS in healthy individuals, as it may also lead to both altered network activity and a behavioral change in cognitive performance in individuals without schizophrenia or schizoaffective disorder. If successful, this study will have identified a safe, effective, and broadly applicable treatment for cognitive impairment in schizophrenia that has potential for translation into many other psychiatric and neurodevelopmental disorders, such as autism.
Waitlist Available
Has No Placebo
Vanderbilt Psychiatric HospitalHeather Ward, MD
Have you considered Edex clinical trials? We made a collection of clinical trials featuring Edex, we think they might fit your search criteria.Go to Trials
Have you considered Edex clinical trials? We made a collection of clinical trials featuring Edex, we think they might fit your search criteria.Go to Trials
Image of CAMC Memorial in Charleston, United States.

Ketamine vs Fentanyl for Sedation in Interventional Radiology

18 - 90
All Sexes
Charleston, WV
This study aims to reduce pain during interventional radiology (IR) procedures, making the experience better for patients. Typically, doctors use medications like fentanyl and midazolam for sedation. This research will focus on patients undergoing biopsies and drainage procedures, often associated with significant discomfort. Patients will be randomly assigned to receive either fentanyl/midazolam or ketamine/midazolam combinations for sedation. A coordinator will collect information on pain levels and satisfaction, as well as monitor any extra medications needed and side effects. The investigators hope to find that ketamine helps decrease pain and improves satisfaction compared to fentanyl, without increasing complications.
Phase < 1
Recruiting
CAMC MemorialAmy R Deipolyi, M.D., Ph.D.
Image of Case Western Reserve University in Cleveland, United States.

Psychosocial Rehabilitation for Schizophrenia

18 - 50
All Sexes
Cleveland, OH
The purpose of this study is to understand how different types of community-based mental health care affect thinking abilities, daily functioning, and brain activity in adults with schizophrenia and related conditions. The investigators are especially interested in learning whether the Clubhouse Model-a structured, supportive community for individuals with mental illness-has unique benefits compared to standard outpatient mental health services. If participants decide to join, they will be asked to complete a total of six study visits with the research team over the course of your participation. Three of these study visits are at the beginning (baseline) and the remaining three are six months later. Two of the three visits will includes interviews, questionnaires, and thinking and memory tasks (cognitive testing) and one session will be an MRI brain scan, which is a safe and non-invasive imaging procedure. The total time required for each visit will be approximately 90 minutes to two hours. Participants may take breaks as needed.
Waitlist Available
Has No Placebo
Case Western Reserve UniversityJessica A Wojtalik, PhD
Have you considered Edex clinical trials? We made a collection of clinical trials featuring Edex, we think they might fit your search criteria.Go to Trials
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security