Apple Cider Vinegar for Prostate Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests whether apple cider vinegar can help men with a type of prostate cancer that has spread but still responds to hormone therapy. Researchers aim to determine if the vinegar increases Akkermansia muciniphila, a beneficial gut bacteria that might improve metabolism and bone health. Participants will either follow standard care or take vinegar caplets daily for three months. Men with metastatic prostate cancer who haven't recently undergone hormone therapy and aren't currently using vinegar supplements might be suitable candidates. As an Early Phase 1 trial, this research focuses on understanding how the treatment works in people, offering participants a chance to contribute to groundbreaking research.
Will I have to stop taking my current medications?
The trial requires that you stop taking antibiotics for a washout period (time without taking certain medications) and remain off them for the duration of the trial. Other medications are not specifically mentioned, so it's best to discuss with the trial team.
Is there any evidence suggesting that this treatment is likely to be safe for humans?
Previous studies have found apple cider vinegar (ACV) to be safe when consumed in moderation, typically up to 1-2 tablespoons mixed with water daily. This indicates it is generally well-tolerated. Research shows that the main ingredient in ACV, acetic acid, is under study for potential health benefits, including effects on cancer cells.
Although no direct evidence supports ACV as a cancer treatment, it is considered relatively safe. People have used it for various health reasons without major issues. Some side effects may include digestive problems like an upset stomach, especially if not properly diluted. However, these cases are rare and usually mild.
This trial is in the early stages, focusing on ensuring ACV's safety and understanding how the body processes it. Early trials often prioritize safety over proving effectiveness. Given its current use for other conditions, researchers expect it to be safe for most participants in this trial.12345Why do researchers think this study treatment might be promising for prostate cancer?
Unlike the standard treatments for prostate cancer, which often include hormone therapy, radiation, or surgery, this approach uses apple cider vinegar, specifically in the form of Jamison apple cider vinegar caplets. Researchers are excited about this treatment because it introduces a natural product known for its potential health benefits, aiming to explore its effects on prostate cancer. The unique aspect here is the active ingredient: acetic acid, which may offer a new mechanism of action by potentially affecting cancer cells differently than traditional therapies. This could provide an alternative for patients seeking less invasive or natural treatment options.
What evidence suggests that apple cider vinegar might be an effective treatment for prostate cancer?
Research has shown that apple cider vinegar contains acetic acid, which can kill cancer cells in lab studies. However, no direct evidence supports apple cider vinegar as a treatment for prostate cancer in people. In this trial, one group of participants will receive apple cider vinegar caplets to study its effects. Scientists are also investigating whether it can increase levels of a beneficial gut bacterium called Akkermansia muciniphila, which might improve overall health and bone strength. Although some people believe in the health benefits of apple cider vinegar, it is not a proven cure for any cancer. More research is needed to understand its potential effects on prostate cancer.12345
Who Is on the Research Team?
Melissa Huynh, MD
Principal Investigator
Western University
Are You a Good Fit for This Trial?
This trial is for patients with metastatic, castration-sensitive prostate cancer who have undergone CT imaging of the abdomen and pelvis along with a bone scan. It's not suitable for individuals who don't meet these imaging requirements.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive 1 acetate caplet per day for 3 months
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Akkermansia Muciniphilia
- Apple Cider Vinegar
Find a Clinic Near You
Who Is Running the Clinical Trial?
Western University
Lead Sponsor